The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease PDF Author: Bharat B. Aggarwal
Publisher: Springer Science & Business Media
ISBN: 0387464018
Category : Medical
Languages : en
Pages : 502

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Book Description
The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Studies on Biomarkers and New Targets in Aging Research in Iran

Studies on Biomarkers and New Targets in Aging Research in Iran PDF Author: Paul C. Guest
Publisher: Springer
ISBN: 9783030561529
Category : Science
Languages : en
Pages : 381

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Book Description
The Middle East is known as the cradle of civilization. It was the crossroads of ancient empires and the birthplace of major world religions. Today it is the center of many world issues due to its economic, religious and political importance. Although it has lagged behind many other regions of the world in medicinal research, this has increased dramatically in recent years with increasing numbers of relevant publications and the country of Iran has spearheaded this progress. Much of the research has focused on increasing our understanding of the aging process and attempting to identify biomarkers and natural products to improve the human healthspan. This book provides a comprehensive overview of the research conducted in the Middle East on the health benefits of curcumin, a phytochemical derived from the famous spice turmeric. Hundreds of studies have now been published describing the health benefits of this spice. The importance of this research is exemplified by poor data regarding health and longevity as only 0.08% of the population in Iran consists of individuals over 90 years of age. This is approximately 10 times lower than the percentage of this same age group in the United Kingdom and the United States of America and almost 20 times lower than that in Japan. This book presents a series of reviews and meta-studies describing research which has resulted in identification potential new biomarkers and drug targets for age-related disorders. All of the studies have focussed on the testing of curcumin and related products, which have already shown some promising leads in age-related conditions such as heart-disease, diabetes, cognitive impairment and cancer. The authors in this series come from different centers and cities of Iran, including Mashhad, Tehran, Isfahan, Ahvaz, Birjand, Quchan and Yazd, and many of the chapters feature collaborations with other countries of the Middle East and throughout the world, including Brazil, Italy, Mexico, Oman, Poland, Switzerland, the United Kingdom and the United States of America. This underscores the emergence of the Middle East into this arena of research. The book will be of high interest to scientific and clinical researchers in the subject of aging and age-related disease, and to physicians and pharmaceutical company scientists since it gives insights into the latest strategies, biomarkers and targets involved in the mechanism of action of curcumin to promote healthy aging. It will also provide important information on disease mechanisms related to age-related disorders, as each chapter will be presented in the context of specific chronic diseases.

Encyclopedia of Dietary Supplements

Encyclopedia of Dietary Supplements PDF Author: Paul M. Coates
Publisher: CRC Press
ISBN: 1498702252
Category : Health & Fitness
Languages : en
Pages : 918

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Book Description
Encyclopedia of Dietary Supplements presents peer-reviewed, objective entries that rigorously examine the most significant scientific research on basic chemical, preclinical, and clinical data. Designed for healthcare professionals, researchers, and health-conscious consumers, it presents evidence-based information on the major vitamin and mineral micronutrients, herbs, botanicals, phytochemicals, and other bioactive preparations. Supplements covered include: Vitamins, beta-carotene, niacin, and folate Omega-3 and omega-6 fatty acids, isoflavones, and quercetin Calcium, copper, iron, and phosphorus 5-hydroxytryptophan, glutamine, and L-arginine St. John's Wort, ginkgo biloba, green tea, kava, and noni Androstenedione, DHEA, and melatonin Coenzyme Q10 and S-adenosylmethionine Shiitake, maitake, reishi, and cordiceps With nearly 100 entries contributed by renowned subject-specific experts, the book serves as a scientific checkpoint for the many OTC supplements carried in today's nutritional products marketplace. Also Available OnlineThis Taylor & Francis encyclopedia is also available through online subscription, offering a variety of extra benefits for researchers, students, and librarians, including: Citation tracking and alerts Active reference linking Saved searches and marked lists HTML and PDF format options Contact Taylor and Francis for more information or to inquire about subscription options and print/online combination packages. US: (Tel) 1.888.318.2367; (E-mail) [email protected] International: (Tel) +44 (0) 20 7017 6062; (E-mail) [email protected]

Herbal Medicine

Herbal Medicine PDF Author: Mark Blumenthal
Publisher: American Botanical Council
ISBN:
Category : Health & Fitness
Languages : en
Pages : 552

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Book Description
This well referenced, instructive, and clinically accurate guide provides everything you need to know about the safe and effective use of medicinal herbs. Published by the American Botanical Council (ABC), the book contains comprehensive, scientifically based information on 29 herbs and 13 proprietary herbal products. The reference is also the first of its kind to include a continuing education module for a wide variety of healthcare professionals. Each herb analysis includes an extensively referenced therapeutic Monograph, a 2-page Clinical Overview for quick reference, and a 1-page Patient Information Sheet for the health professional to copy and give to patients. Pharmacological activity, herb-drug interactions, adverse effects, preparations, dosage, name brands, regulations, and detailed tables of clinical studies, are all accurately presented in this important educational guidebook. Key features of the ABC Guide: In depth data - thorough and detailed information for the most popular herbs and herbal products sold in the US market today More than 40 tables of clinical studies, including 180 commercial products Incorporation of science-based and traditional information Standardized and regimented layout ensures quick and easy access to information National continuing education credit - 10 to 13.5 credit hours available to health professionals in five disciplines Message to customers: The University of Texas Medical Branch at Galveston (UTMB) has extended CME credit for physicians for The ABC Clinical Guide to Herbs. The current $20 fee will no longer be charged. This will now be offered at no cost with purchase of the book. In addition, CE credit has been extended for nurses, pharmacists, and dietitians. THE ABC CLINICAL GUIDE to HERBS provides healthcare professionals with what they want: factual, current, scientifically based information and guidance on the top selling herbs in the United States. A must have reference for every practice Published by the American Botanical Council. Thieme is proud to be the exclusive worldwide distributor for this book.

Herbal Medicine

Herbal Medicine PDF Author: Iris F. F. Benzie
Publisher: CRC Press
ISBN: 1439807167
Category : Health & Fitness
Languages : en
Pages : 488

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Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Turmeric Curcumin Cures

Turmeric Curcumin Cures PDF Author: Sharon Daniels
Publisher: Speedy Publishing LLC
ISBN: 1632876582
Category : Health & Fitness
Languages : en
Pages : 40

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Book Description
Tired of natural "cures" that lead nowhere? Looking for a fact-based, reliable, natural remedy? Look no further! Modern medicine and natural health are often at odds, but not always. This latest volume of the Miracle Healers from the Kitchen series by Sharon Daniels delves deep into the facts about turmeric. This miraculous spice is the subject of more than 1,000 medical studies, and has convinced numerous medical professionals and scientists alike that some herbs really are miraculous. Turmeric effectively treats a host of conditions. It is being tested for treatment on everything from arthritis pain to cancer, and the results are promising. Don't let inflammatory diseases slow you down. Turmeric cures, and bestselling author Sharon Daniels tells you how and why. In this incredible volume, you will learn about components of turmeric, like the powerful and widely-acclaimed curcumin: "Curcumin, a natural product isolated from the spice turmeric, has been shown to exhibit a wide range of pharmacological activities including certain anti-cancer properties. It has been specifically shown to be an effective inhibitor of angiogenesis both in vitro and in vivo." Robinson,TP, et al. Bioorg Med Chem. 2005 Jun 2;13(12):4007-13. Synthesis and biological evaluation of aromatic enones related to curcumin. You'll also find out what foods contain the spice, and how to use it for maximum effectiveness. Don't let age and inflammation bog you down. Take charge of your health. Learn about turmeric today, when you buy Turmeric Cures. A healthier you is just one book away.

PDR for Nutritional Supplements

PDR for Nutritional Supplements PDF Author: Sheldon Saul Hendler
Publisher: Physician's Desk Reference (PDR)
ISBN: 9781563637100
Category : Dietary supplements
Languages : en
Pages : 0

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Book Description
Physicians can use this fact-filled second edition to advise patients in their quest to learn about proper use of supplements and functional foods. Now updated and including new information on functional foods.

Curcumin in Health and Disease

Curcumin in Health and Disease PDF Author: Beatrice E. Bachmeier
Publisher: MDPI
ISBN: 3039214497
Category : Medical
Languages : en
Pages : 274

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Book Description
The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

WHO Monographs on Selected Medicinal Plants

WHO Monographs on Selected Medicinal Plants PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9789241545372
Category : Health & Fitness
Languages : en
Pages : 392

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Book Description
This is the second volume in a series of monographs which are intended to promote information exchange and international harmonised standards for the quality control and use of herbal medicines. It contains scientific information on 30 selected plants, and each entry includes a pharmacopoeial summary for quality assurance purposes, information on its clinical application and sections on contraindications, pharmacology, safety issues, and dosage forms. It provides two cumulative indexes with entries in alphabetical order by plant name and according to the plant material of interest.

Medical Medium Celery Juice

Medical Medium Celery Juice PDF Author: Anthony William
Publisher: Hay House, Inc
ISBN: 1401957668
Category : Health & Fitness
Languages : en
Pages : 459

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Book Description
Celery juice is everywhere for a reason: because it's saving lives as it restores people's health one symptom at a time. From celebrities posting about their daily celery juice routines to people from all walks of life sharing pictures and testimonials of their dramatic recovery stories, celery juice is revealing itself to ignite healing when all odds seem against it. What began decades ago as a quiet movement has become a global healing revolution. In Celery Juice: The Most Powerful Medicine of Our Time Healing Millions Worldwide, Anthony William, the originator of the global celery juice movement, introduces you to celery juice's incredible ability to create sweeping improvements on every level of our health: Healing the gut and relieving digestive disorders Balancing blood sugar, blood pressure, weight, and adrenal function Neutralizing and flushing toxins from the liver and brain Restoring health in people who suffer from a vast range of chronic and mystery illnesses and symptoms, among them fatigue, brain fog, acne, eczema, addiction, ADHD, thyroid disorders, diabetes, SIBO, eating disorders, autoimmune disorders, Lyme disease, and eye problems After revealing exactly how celery juice does its anti-inflammatory, alkalizing, life-changing work to provide these benefits and many more, he gives you the powerful, definitive guidelines to do your own celery juice cleanse correctly and successfully. You'll get instructions on how to make the juice, how much to drink, when to drink it, and what to expect as your body begins to detox, plus answers to FAQs such as "Is it safe to drink celery juice while pregnant or breastfeeding?", "Is blending better than juicing?", and "Can I take my medications with it?" Here is everything you need to know--from the original source--to receive the full gift of what Anthony calls "one of the greatest healing tonics of all time."