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Author: Mary Mann Hamilton
Publisher: Little, Brown
ISBN: 0316341363
Category : Biography & Autobiography
Languages : en
Pages : 336
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Book Description
The astonishing first-person account of Mississippi pioneer woman struggling to survive, protect her family, and make a home in the early American South. Near the end of her life, Mary Mann Hamilton (1866 - c.1936) began recording her experiences in the backwoods of the Mississippi Delta. The result is this astonishing first-person account of a pioneer woman who braved grueling work, profound tragedy, and a pitiless wilderness (she and her family faced floods, tornadoes, fires, bears, panthers, and snakes) to protect her home in the early American South. An early draft of Trials of the Earth was submitted to a writers' competition sponsored by Little, Brown in 1933. It didn't win, and we almost lost the chance to bring this raw, vivid narrative to readers. Eighty-three years later, in partnership with Mary Mann Hamilton's descendants, we're proud to share this irreplaceable piece of American history. Written in spare, rich prose, Trials of the Earth is a precious record of one woman's extraordinary endurance and courage that will resonate with readers of history and fiction alike.
Author: Mary Mann Hamilton
Publisher: Little, Brown
ISBN: 0316341363
Category : Biography & Autobiography
Languages : en
Pages : 336
Get Book Here
Book Description
The astonishing first-person account of Mississippi pioneer woman struggling to survive, protect her family, and make a home in the early American South. Near the end of her life, Mary Mann Hamilton (1866 - c.1936) began recording her experiences in the backwoods of the Mississippi Delta. The result is this astonishing first-person account of a pioneer woman who braved grueling work, profound tragedy, and a pitiless wilderness (she and her family faced floods, tornadoes, fires, bears, panthers, and snakes) to protect her home in the early American South. An early draft of Trials of the Earth was submitted to a writers' competition sponsored by Little, Brown in 1933. It didn't win, and we almost lost the chance to bring this raw, vivid narrative to readers. Eighty-three years later, in partnership with Mary Mann Hamilton's descendants, we're proud to share this irreplaceable piece of American history. Written in spare, rich prose, Trials of the Earth is a precious record of one woman's extraordinary endurance and courage that will resonate with readers of history and fiction alike.
Author: Mark Fiege
Publisher: University of Washington Press
ISBN: 0295804149
Category : History
Languages : en
Pages : 601
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Book Description
In the dramatic narratives that comprise The Republic of Nature, Mark Fiege reframes the canonical account of American history based on the simple but radical premise that nothing in the nation's past can be considered apart from the natural circumstances in which it occurred. Revisiting historical icons so familiar that schoolchildren learn to take them for granted, he makes surprising connections that enable readers to see old stories in a new light. Among the historical moments revisited here, a revolutionary nation arises from its environment and struggles to reconcile the diversity of its people with the claim that nature is the source of liberty. Abraham Lincoln, an unlettered citizen from the countryside, steers the Union through a moment of extreme peril, guided by his clear-eyed vision of nature's capacity for improvement. In Topeka, Kansas, transformations of land and life prompt a lawsuit that culminates in the momentous civil rights case of Brown v. Board of Education. By focusing on materials and processes intrinsic to all things and by highlighting the nature of the United States, Fiege recovers the forgotten and overlooked ground on which so much history has unfolded. In these pages, the nation's birth and development, pain and sorrow, ideals and enduring promise come to life as never before, making a once-familiar past seem new. The Republic of Nature points to a startlingly different version of history that calls on readers to reconnect with fundamental forces that shaped the American experience. For more information, visit the author's website: http://republicofnature.com/
Author: David Attenborough
Publisher: HarperCollins UK
ISBN: 0008477884
Category : Nature
Languages : en
Pages : 409
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Book Description
The third and final updated edition of David Attenborough’s classic Life trilogy. Life on Earth covered evolution, Living Planet , ecology, and now The Trials of Life tackles ethology, the study of how animals behave.
Author: Laurie M. Carlson
Publisher: Ivan R. Dee Publisher
ISBN:
Category : History
Languages : en
Pages : 232
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Book Description
Laurie Winn Carlson offers an innovative explanation for the madness behind the Salem Witch Trials.
Author: Leonard A. Parry
Publisher: Beard Books
ISBN: 9781587980312
Category : Law
Languages : en
Pages : 354
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Book Description
Author: Robert Bazell
Publisher: Random House
ISBN: 0307764982
Category : Health & Fitness
Languages : en
Pages : 241
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Book Description
Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.
Author: Mary Ann Kelty
Publisher:
ISBN:
Category :
Languages : en
Pages : 976
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Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Thomas Bayly Howell
Publisher:
ISBN:
Category : Trials
Languages : en
Pages : 736
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Book Description
Author: Stuart J. Pocock
Publisher: John Wiley & Sons
ISBN: 1118794109
Category : Medical
Languages : en
Pages : 228
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Book Description
This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general perspective on their historical development, current status, and future strategy. Features examples derived from the author's personal experience.
