Collagen

Collagen PDF Author: Marcel E. Nimni
Publisher: CRC Press
ISBN: 135108769X
Category : Medical
Languages : en
Pages : 516

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Book Description
This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Collagen

Collagen PDF Author: Marcel E. Nimni
Publisher: CRC Press
ISBN: 135108769X
Category : Medical
Languages : en
Pages : 516

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Book Description
This series was conceived with the idea of integrating current aspects of ongoing research in the collagen field. The book consists of a spectrum of papers which discus divers aspects such as X-ray structure, the thermodynamics and mechanism of fibrillogenesis, and the use of collagen as a biomaterial for the manufacturing of many implantable, sometimes lifesaving, devises.

Biochemistry of Collagen

Biochemistry of Collagen PDF Author: Gopalasamudram Ramachandran
Publisher: Springer Science & Business Media
ISBN: 1475746024
Category : Science
Languages : en
Pages : 546

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Book Description
Collagen is a fascinating protein not only because of its ubiquitous occurrence in multicellular animals, but also because of its unique chemi cal structure. As the predominant constituent in bone, cartilage, skin, tendon, and tooth, it is not surprising that collagen is of interest to anatomists, biochemists, biomedical engineers, cell biologists, dermatolo gists, dental surgeons, leather chemists, orthopedic surgeons, physiologists, physicians, zoologists, and a host of others. This book was planned to provide an up-to-date comprehensive survey of all aspects of biochemistry of collagen. The recent discovery of genetically distinct collagens with tissue specificity has opened a new era in collagen biochemistry, and Karl Piez discusses this in the opening chapter on primary structure. In the next chapter, Ramachandran and Rama krishnan deal with the molecular structure of collagen, placing special emphasis on the conformational aspects of its polypeptide chains. Follow ing the consideration of primary and secondary structure of collagen, the three-dimensional arrangement of collagen molecules in the fibrils is covered by Miller in Chapter 3. Collagen is generally in the insoluble state in the living organism due to the cross-linking of individual molecules, and Tanzer describes the various aspects of this cross-linkage in Chapter 4. The biosynthesis of collagen is discussed in depth by Prockop and his colleagues.

The Collagen Superfamily and Collagenopathies

The Collagen Superfamily and Collagenopathies PDF Author: Florence Ruggiero
Publisher: Springer Nature
ISBN: 3030675920
Category : Science
Languages : en
Pages : 343

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Book Description
This book aims at providing insights into the collagen superfamily and the remarkable diversity of collagen function within the extracellular matrix. Additionally, the mechanisms underlying collagen-related diseases such as dystrophic epidermolysis bullosa, osteogenesis imperfecta, as well as collagen-related myopathies and neurological disorders are discussed. Collagens are the most abundant extracellular matrix proteins in organisms. Their primary function is to provide structural support and strength to cells and to maintain biomechanical integrity of tissues. However, collagens can no longer be considered just as structural proteins. They can act as extracellular modulators of signaling events and serve critical regulatory roles in various cell functions during embryonic development and adult homeostasis. Furthermore, collagens are associated with a broad spectrum of heritability-related diseases known as “collagenopathies” that affect a multitude of organs and tissues including sensorial organs. The book is a useful introduction to the field for junior scientists, interested in extracellular matrix research. It is also an interesting read for advanced scientists and clinicians working on collagens and collagenopathies, giving them a broader view of the field beyond their area of specialization.

Biomedical Engineering Fundamentals

Biomedical Engineering Fundamentals PDF Author: Joseph D. Bronzino
Publisher: CRC Press
ISBN: 143982519X
Category : Medical
Languages : en
Pages : 1144

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Book Description
Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Biomedical Engineering Fundamentals, the first volume of

Cartilage V1

Cartilage V1 PDF Author: Brian K. Hall
Publisher: Academic Press
ISBN: 0323139582
Category : Science
Languages : en
Pages : 402

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Book Description
Cartilage, Volume 1: Structure, Function, and Biochemistry provides an in-depth treatment of cartilage structure, function, and biochemistry. Topics range from vertebrate and invertebrate cartilages to chondroblasts and chondrocytes, along with the use of transmission electron microscopy and scanning electron microscopy to examine cartilage. The collagens and cell kinetics of cartilage are also discussed. Comprised of 12 chapters, this volume begins with an overview of the diversity of cartilage in vertebrates and invertebrates in terms of structure, function, and evolution. The principal common attributes of vertebrate cartilages as well as those specific parameters that usefully serve to distinguish between cartilaginous tissues at several phylogenetic levels are discussed. Function and level of function are considered, along with their correlations with the structural attributes of a specific cartilage. Subsequent chapters explore the chondroblasts and chondrocytes of cartilage, particularly how they arise and how they are maintained; the ultrastructure of cartilage; the biochemistry of cartilaginous extracellular matrices; and the kinetic and metabolic properties of cartilage cells. The final chapter analyzes the mechanisms of calcification of cartilage. This book will be of interest to biologists and biochemists.

Heart Perfusion, Energetics, and Ischemia

Heart Perfusion, Energetics, and Ischemia PDF Author: Leopold Dintenfass
Publisher: Springer Science & Business Media
ISBN: 1475703937
Category : Science
Languages : en
Pages : 697

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Book Description
The principal purpose of a NATO (North Atlantic Treaty Organization) Advanced Research Workshop, a part of the NATO Advanced Study Institutes Programme, is to: (a) exchange thoughts at the frontiers of knowledge or at the frontiers of two (or more) fields or sectors; (b) review and assess the state of the art; (c) formulate recommendations for future research directions; (d) formulate plans for large international scientific experiments. The aim of the ARW on "Microvascular, rheological, metabolic and heat-transfer aspects of the heart: relation to ischaemia and thrombosis", convened in Chateau de Bonas, July 4-11, 1982, was to describe functions and performance of the heart in an interdisciplin ary effort, involving cardiologists, pathologists, biochemists, haemorheologists, physiologists, pharmacologists and bioengineers; to explore interactions between such subfields as blood rheology, micro circulation and ischaemia of the myocardium, heat transfer, heat work and performance as a pump, effect of -metabolites and ion transfer, mechanism of sudden death, protein synthesis and protein molecular transformations. One of the purposes of the Convenor was to relate clinical haemorheology to the heart energetics and heart metabolism. This was only partly established, as difficulties of communications between different fields, difficulties of semantics and of specialized out looks could not be overcome within a -few days. Nevertheless, a gate was opened for communications interchange in the future. There was even a problem within each specialty, and as is rather common, quite diverse views have been expressed. This, of course, is quite normal in the progress of science.

Biomaterials

Biomaterials PDF Author: Joyce Y. Wong
Publisher: CRC Press
ISBN: 1439874190
Category : Medical
Languages : en
Pages : 271

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Book Description
Most current applications of biomaterials involve structural functions, even in those organs and systems that are not primarily structural in their nature, or very simple chemical or electrical functions. Complex chemical functions, such as those of the liver, and complex electrical or electrochemical functions, such as those of the brain and sense

Current Topics in Pathology

Current Topics in Pathology PDF Author: E. Grundmann
Publisher: Springer Science & Business Media
ISBN: 3642658571
Category : Medical
Languages : en
Pages : 367

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Book Description


Molecular Cytogenetics

Molecular Cytogenetics PDF Author: Barbara Hamkalo
Publisher: Springer Science & Business Media
ISBN: 146157479X
Category : Medical
Languages : en
Pages : 354

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Book Description
This volume represents the Proceedings of the Twenty-Sixth Annual Biology Division Research Conference held April 9-12, 1973 in Gatlinburg, Tennessee. The subject of the symposium was Molecular Cytogenetics and the aim of the meeting was to bring together researchers interested in problems of chromosome organi zation, activity and regulation in prokaryotes and eukaryotes. Cytological, biochemical and genetic approaches to these questions were included since the collective information gained from these disciplines provides an integrated approach to genome structure and function. The meeting was sponsored by the Biology Division of the Oak Ridge National Laboratory*. It would not have been possible with out the interest and cooperation of the organizing committee under the chairmanship of O. L. Miller, Jr. Special thanks are due to the chairmen and speakers for making this volume possible and to Dr. Waldo Cohn for his assistance in editing. Preparation of the completed volume was due in large part to the efforts of Sandra Vaughan of the Biology Division. The Editors Barbara Ann Hamkalo John Papaconstantinou August, 1973 * Operated by the Union Carbide Corporation for the U.S. Atomic Energy Commission.

Mechanical Design in Organisms

Mechanical Design in Organisms PDF Author: Stephen A. Wainwright
Publisher: Princeton University Press
ISBN: 0691218099
Category : Science
Languages : en
Pages : 440

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Book Description
This book deals with an interface between mechanical engineering and biology. Available for the first time in paperback, it reviews biological structural materials and systems and their mechanically important features and demonstrates that function at any particular level of biological integration is permitted and controlled by structure at lower levels of integration. Five chapters discuss the properties of materials in general and those of biomaterials in particular. The authors examine the design of skeletal elements and discuss animal and plant systems in terms of mechanical design. In a concluding chapter they investigate organisms in their environments and the insights gained from study of the mechanical aspects of their lives.