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Author:
Publisher: Elsevier
ISBN: 0444640770
Category : Medical
Languages : en
Pages : 480
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Book Description
Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Author:
Publisher: Elsevier
ISBN: 0444640770
Category : Medical
Languages : en
Pages : 480
Get Book Here
Book Description
Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. Contains comprehensive coverage of neurogenetics Details the latest science and its impact on our understanding of neurological, psychiatric disorders Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Author:
Publisher: Elsevier
ISBN: 0444639535
Category : Medical
Languages : en
Pages : 512
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Book Description
Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309168597
Category : Medical
Languages : en
Pages : 125
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Book Description
In Advancing Prion Science, the Institute of Medicine's Committee on Transmissible Spongiform Encephalopathies Assessment of Relevant Science recommends priorities for research and investment to the Department of Defense's National Prion Research Program (NPRP). Transmissible spongiform encephalopathies (TSEs), also called prion diseases, are invariably fatal neurodegenerative infectious diseases that include bovine spongiform encephalopathy (commonly called mad cow disease), chronic wasting disease, scrapie, and Creutzfeldt-Jakob disease. To develop antemortem diagnostics or therapies for TSEs, the committee concludes that NPRP should invest in basic research specifically to elucidate the structural features of prions, the molecular mechanisms of prion replication, the mechanisms of TSE pathogenesis, and the physiological function of prions' normal cellular isoform. Advancing Prion Science provides the first comprehensive reference on present knowledge about all aspects of TSEs' from basic science to the U.S. research infrastructure, from diagnostics to surveillance, and from prevention to treatment. This report summarizes the progress thus far.
Author: European Commission. Directorate General for Research
Publisher:
ISBN:
Category : Bovine spongiform encephalopathy
Languages : en
Pages : 58
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Book Description
This booklet highlights the research response of the European Commission to the spectrum of diseases known as the Transmissible Spongiform Encephalopathies (TSEs), which include BSE (primarily a disease of cattle), scrapie in sheep and goats (small ruminants) and variant and classical or sporadic CJD in man. It also provides information on three of the larger research programmes carried out in Member States of the European Union. The booklet focuses on key projects funded by the Directorate-General for Research from the mid 1990s to the present day, and in doing so, aims to give an overview of the important work carried out in the past, as well as of current research priorities.
Author: Sophie Lerouge
Publisher: Elsevier
ISBN: 0857096265
Category : Medical
Languages : en
Pages : 347
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Book Description
The effective sterilisation of any material or device to be implanted in or used in close contact with the human body is essential for the elimination of harmful agents such as bacteria. Sterilisation of biomaterials and medical devices reviews established and commonly used technologies alongside new and emerging processes.Following an introduction to the key concepts and challenges involved in sterilisation, the sterilisation of biomaterials and medical devices using steam and dry heat, ionising radiation and ethylene oxide is reviewed. A range of non-traditional sterilisation techniques, such as hydrogen peroxide gas plasma, ozone and steam formaldehyde, is then discussed together with research in sterilisation and decontamination of surfaces by plasma discharges. Sterilisation techniques for polymers, drug-device products and tissue allografts are then reviewed, together with antimicrobial coatings for ‘self-sterilisation’ and the challenge presented by prions and endotoxins in the sterilisation of reusable medical devices. The book concludes with a discussion of future trends in the sterilisation of biomaterials and medical devices.With its distinguished editors and expert team of international contributors, Sterilisation of biomaterials and medical devices is an essential reference for all materials scientists, engineers and researchers within the medical devices industry. It also provides a thorough overview for academics and clinicians working in this area. Reviews established and commonly used technologies alongside new and emerging processes Introduces and reviews the key concepts and challenges involved in sterilisation Discusses future trends in the sterilisation of biomaterials and medical devices
Author: Dimitry Konstantinovich Lvov
Publisher: Academic Press
ISBN: 0128018445
Category : Science
Languages : en
Pages : 453
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Book Description
Zoonotic Viruses of Northern Eurasia: Taxonomy and Ecology provides a review of modern data of the taxonomy, distribution, and ecology of zoonotic viruses in the ecosystems of Northern Eurasia. With climate changes, increasing population density of arthropod vectors and vertebrate hosts, development of unused lands, transferences of viruses by birds, bats, infected humans, and animals, vectors allow virus populations to adapt to the new environment. This leads to the appearance of emerging or re-emerging infections. This book presents data about circulation and evolution of influenza viruses, tick-borne encephalitis virus, West Nile virus, Crimean-Congo hemorrhagic fever virus, hantaviruses, Sindbis virus, California encephalitis group viruses and other pathogenic viruses as well as of novel viruses classified for the first time using next-generation sequence. Features summarized data about the circulation of approximately 80 viruses isolated in natural foci of Northern Eurasia Provides descriptions of the main ecosystems of Northern Eurasia in the context of the ecology of viruses with environmental factors Delineates the potential impact of climate change for the distribution of viruses Includes virus taxonomy, ecology, distribution and pathogenicity for humans and animals
Author: Maxime Schwartz
Publisher: Univ of California Press
ISBN: 0520243374
Category : Medical
Languages : en
Pages : 264
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Book Description
"How the Cows Turned Mad tells the story of a disease that continues to elude on many levels. Yet science has come far in understanding its origins, incubation, and transmission. This book is a case history that illuminates the remarkable progression of science."--BOOK JACKET.
Author: Charlotte A. Spencer
Publisher: Prentice Hall
ISBN: 9780131423398
Category : Beef cattle
Languages : en
Pages : 0
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Book Description
Part of the Prentice Hall Exploring Biology Series, Mad Cows and Cannibals explores the biological, political and social aspects of transmissible spongiform encephalopathies, including Mad Cow Disease and Chronic Wasting Disease. The text begins with stories of ritualistic cannibalism in the highlands of New Guinea, and leads to the modern agricultural feeding practices that triggered the Mad Cow Disease epidemic in Great Britain, and to recent outbreaks of Chronic Wasting Disease in North America. In clear and accessible language, it explains the biology of these bizzare, degenerative brain diseases, answering important questions about how TSEs affect the safety of our food supply, blood supply, and medical procedures.
Author:
Publisher:
ISBN:
Category : Prion diseases
Languages : en
Pages : 52
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Book Description
Author: O.-R. Kaaden
Publisher: Springer Science & Business Media
ISBN: 3709193001
Category : Science
Languages : en
Pages : 307
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Book Description
Among unconventional agents and unclassified viruses the contributions to this volume focused on prion-related diseases, with special emphasis on bovine spongiform encephalopathy and human spongiform encephalopathies, and Borna disease virus, an agent known since long time to be pathogenic for horses and sheep, which is now discussed as a potential pathogen for humans. Additionally, the volume contains articles about newly discovered viruses like porcine respiratory and reproductive syndrome virus and viruses that are classified only provisionally like African swine fever virus, hepatitis C and E viruses, or the arteriviruses.
