Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water PDF Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: IARC Monographs on the Evaluat
ISBN: 9789283213246
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water PDF Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: IARC Monographs on the Evaluat
ISBN: 9789283213246
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.

Toxicological Profile for Di(2-ethylhexyl) Phthalate (DEHP)

Toxicological Profile for Di(2-ethylhexyl) Phthalate (DEHP) PDF Author:
Publisher:
ISBN:
Category : Diethylhexyl phthalate
Languages : en
Pages : 186

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Book Description


Phthalates and Cumulative Risk Assessment

Phthalates and Cumulative Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309128412
Category : Nature
Languages : en
Pages : 208

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Book Description
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.

Toxicological Profile for Di(2-ethylhexyl) Phthalate (DEHP)

Toxicological Profile for Di(2-ethylhexyl) Phthalate (DEHP) PDF Author:
Publisher:
ISBN:
Category : Phthalate esters
Languages : en
Pages : 300

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Book Description


Toxicological profile for di(2-ethylhexyl)phthalate

Toxicological profile for di(2-ethylhexyl)phthalate PDF Author:
Publisher:
ISBN:
Category : Diethylhexyl phthalate
Languages : en
Pages : 348

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Book Description


Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals

Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309458625
Category : Science
Languages : en
Pages : 423

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Book Description
To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects.

Toxicological Profile for DI (2-Ethylhexyl) Phthalate (DEHP)

Toxicological Profile for DI (2-Ethylhexyl) Phthalate (DEHP) PDF Author:
Publisher:
ISBN: 9780756708351
Category :
Languages : en
Pages : 161

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Book Description
This report provides information about Di (2-Ethylhexyl) Phthalate (DEHP) & the human health effects of exposure. This chemical has been found in many sites identified by the EPA for long-term Federal cleanup activities. The report includes a Public Health Statement which explains the toxicologic properties of DEHP in a nontechnical, Q&A format, & a review of the general health effects observed following exposure; a description of health effects; how the chemical can affect children; & information on its chemical & physical properties, production, use & disposal, potential for human exposure, analytical methods, & regulations & advisories.

Taking an Exposure History

Taking an Exposure History PDF Author: Arthur L. Frank
Publisher:
ISBN:
Category : Environmental monitoring
Languages : en
Pages : 60

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Book Description


Draft Toxicological Profile for Di(2-ethylhexyl)phthalate

Draft Toxicological Profile for Di(2-ethylhexyl)phthalate PDF Author:
Publisher:
ISBN:
Category : DI(2-ethylhexyl) phthalate
Languages : en
Pages : 296

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Book Description


Toxicological Profile for Diethyl Phthalate

Toxicological Profile for Diethyl Phthalate PDF Author:
Publisher:
ISBN:
Category : Phthalic acid
Languages : en
Pages : 164

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Book Description