Towards 4D Bioprinting

Towards 4D Bioprinting PDF Author: Adrian Neagu
Publisher: Academic Press
ISBN: 012818745X
Category : Technology & Engineering
Languages : en
Pages : 302

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Book Description
Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting.In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive technology. The last chapter discusses the perspectives of the field. This book provides an up-to date description of the theoretical tools developed for the optimization of 3D bioprinting, presents the morphogenetic mechanisms responsible for the post-printing evolution of the bioprinted construct and describing computational methods for simulating this evolution, and discusses the leap from 3D to 4D bioprinting in the light of the latest developments in the field. Most importantly, Towards 4D Printing explains the importance of theoretical modeling for the progress of 3D and 4D bioprinting. - Presents theoretical tools needed for the optimization of the bioprinting process - Describes the principles and implementation of computer simulations needed to predict the outcome of 3D bioprinting - Analyzes the distinctive features of 4D bioprinting along with its applications and perspectives

Towards 4D Bioprinting

Towards 4D Bioprinting PDF Author: Adrian Neagu
Publisher: Academic Press
ISBN: 012818745X
Category : Technology & Engineering
Languages : en
Pages : 302

Get Book Here

Book Description
Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting.In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive technology. The last chapter discusses the perspectives of the field. This book provides an up-to date description of the theoretical tools developed for the optimization of 3D bioprinting, presents the morphogenetic mechanisms responsible for the post-printing evolution of the bioprinted construct and describing computational methods for simulating this evolution, and discusses the leap from 3D to 4D bioprinting in the light of the latest developments in the field. Most importantly, Towards 4D Printing explains the importance of theoretical modeling for the progress of 3D and 4D bioprinting. - Presents theoretical tools needed for the optimization of the bioprinting process - Describes the principles and implementation of computer simulations needed to predict the outcome of 3D bioprinting - Analyzes the distinctive features of 4D bioprinting along with its applications and perspectives

Polymer-Based Additive Manufacturing

Polymer-Based Additive Manufacturing PDF Author: Declan M. Devine
Publisher: Springer Nature
ISBN: 3030245322
Category : Medical
Languages : en
Pages : 286

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Book Description
This book aims to give readers a basic understanding of commonly used additive manufacturing techniques as well as the tools to fully utilise the strengths of additive manufacturing through the modelling and design phase all the way through to post processing. Guidelines for 3D-printed biomedical implants are also provided. Current biomedical applications of 3D printing are discussed, including indirect applications in the rapid manufacture of prototype tooling and direct applications in the orthopaedics, cardiovascular, drug delivery, ear-nose-throat, and tissue engineering fields. Polymer-Based Additive Manufacturing: Biomedical Applications is an ideal resource for students, researchers, and those working in industry seeking to better understand the medical applications of additive manufacturing.

Bone Tissue Engineering

Bone Tissue Engineering PDF Author: Jeffrey O. Hollinger
Publisher: CRC Press
ISBN: 1135501912
Category : Medical
Languages : en
Pages : 462

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Book Description
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

3D Bioprinting in Regenerative Engineering

3D Bioprinting in Regenerative Engineering PDF Author: Ali Khademhosseini
Publisher: CRC Press
ISBN: 1315280485
Category : Technology & Engineering
Languages : en
Pages : 403

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Book Description
Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications

Bioresorbable Polymers

Bioresorbable Polymers PDF Author: Declan Devine
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110640570
Category : Medical
Languages : en
Pages : 152

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Book Description
Bioresorbable implants can be processed via conventional polymer processing methods such as extrusion, injection and compressing moulding, solvent spinning or casting. This book addresses issues and highlights recent advances in the use of biodegradable polymers. It is intended for researchers utilizing biodegradable polymers in areas from tissue engineering to controlled release of active pharmaceuticals, as well as industrial processors.

Cell Assembly with 3D Bioprinting

Cell Assembly with 3D Bioprinting PDF Author: Yong He
Publisher: John Wiley & Sons
ISBN: 3527347968
Category : Technology & Engineering
Languages : en
Pages : 370

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Book Description
Provides an up-to-date outline of cell assembly methods and applications of 3D bioprinting Cell Assembly with 3D Bioprinting provides an accesible overview of the layer-by-layer manufacturing of living structures using biomaterials. Focusing on technical implemention in medical and bioengineering applications, this practical guide summarize each key aspect of the 3D bioprinting process. Contributions from a team of leading researchers describe bioink preparation, printing method selection, experimental protocols, integration with specific applications, and more. Detailed, highly illustrated chapters cover different bioprinting approaches and their applications, including coaxial bioprinting, digital light projection, direct ink writing, liquid support bath-assisted 3D printing, and microgel-, microfiber-, and microfluidics-based biofabrication. The book includes practical examples of 3D bioprinting, a protocol for typical 3D bioprinting, and relevant experimental data drawn from recent research. * Highlights the interdisciplinary nature of 3D bioprinting and its applications in biology, medicine, and pharmaceutical science * Summarizes a variety of commonly used 3D bioprinting methods * Describes the design and preparation of various types of bioinks * Discusses applications of 3D bioprinting such as organ development, toxicological research, clinical transplantation, and tissue repair Covering a wide range of topics, Cell Assembly with 3D Bioprinting is essential reading for advanced students, academic researchers, and industry professionals in fields including biomedicine, tissue engineering, bioengineering, drug development, pharmacology, bioglogical screening, and mechanical engineering.

3D Printing in Medicine

3D Printing in Medicine PDF Author: Deepak M. Kalaskar
Publisher: Woodhead Publishing
ISBN: 0323902200
Category : Science
Languages : en
Pages : 424

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Book Description
3D Printing in Medicine, Second Edition examines the rapidly growing market of 3D-printed biomaterials and their clinical applications. With a particular focus on both commercial and premarket tools, the book looks at their applications within medicine and the future outlook for the field. The chapters are written by field experts actively engaged in educational and research activities at the top universities in the world. The earlier chapters cover the fundamentals of 3D printing, including topics such as materials and hardware. The later chapters go on to cover innovative applications within medicine such as computational analysis of 3D printed constructs, personalized 3D printing - including 3D cell and organ printing and the role of AI - with a subsequent look at the applications of high-resolution printing, 3D printing in diagnostics, drug development, 4D printing, and much more. This updated new edition features completely revised content, with additional new chapters covering organs-on-chips, bioprinting regulations and standards, intellectual properties, and socio-ethical implications of organs-on-demand. - Reviews a broad range of biomedical applications of 3D printing biomaterials and technologies - Provides an interdisciplinary look at 3D printing in medicine, bridging the gap between engineering and clinical fields - Includes completely updated content with additional new chapters, covering topics such as organs-on-chips, bioprinting regulations, intellectual properties, medical standards in 3D printing, and more

Smart Materials in Additive Manufacturing, volume 1: 4D Printing Principles and Fabrication

Smart Materials in Additive Manufacturing, volume 1: 4D Printing Principles and Fabrication PDF Author: Mahdi Bodaghi
Publisher: Elsevier
ISBN: 0128240830
Category : Technology & Engineering
Languages : en
Pages : 484

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Book Description
Smart Materials in Additive Manufacturing, Volume 1 provides readers with an overview of the current smart materials widely in use and the techniques for additively manufacturing them. It demonstrates the principles developed for 4D printing in a way that is useful for students, early career researchers, and professionals. Topics covered include modeling and fabrication of 4D printed materials such as dielectric elastomer soft robots, low-voltage electroactive polymers, and stimuli-responsive hydrogels. 4D printing of light-responsive structures, gels and soft materials, and natural fiber composites are also discussed, as is origami-inspired 4D printing, 4D microprinting, and reversible 4D printing. 4D bioprinting and related biomedical applications are outlined as well as functionalized 4D printed sensor systems. Key Features:* Discusses 4D printed shape memory polymers, shape memory alloys, natural fibers, and hydrogels* Covers various types of stimuli, fabrication techniques, multi-physics modeling, and control strategies for 4D printing* Explores 4D printing of dielectric elastomers, liquid crystal elastomers, and electroactive polymers - Covers the mechanics, manufacturing processes and applications of 4D-printed smart materials and structures - Discusses applications in civil, mechanical, aerospace, polymer and biomedical engineering - Presents experimental, numerical and analytical studies in a simple and straightforward manner, providing tools that can be immediately implemented and adapted by readers to fit their work

3D and 4D Printing of Polymer Nanocomposite Materials

3D and 4D Printing of Polymer Nanocomposite Materials PDF Author: Kishor Kumar Sadasivuni
Publisher: Elsevier
ISBN: 0128173025
Category : Technology & Engineering
Languages : en
Pages : 594

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Book Description
3D and 4D Printing of Polymer Nanocomposite Materials: Processing, Applications, and Challenges covers advanced 3D and 4D printing processes and the latest developments in novel polymer-based printing materials, thus enabling the reader to understand and benefit from the advantages of this groundbreaking technology. The book presents processes, materials selection, and printability issues, along with sections on the preparation of polymer composite materials for 3D and 4D printing. Across the book, advanced printing techniques are covered and discussed thoroughly, including fused deposition modeling (FDM), selective laser sintering (SLS), selective laser melting (SLM), electron beam melting (EBM), inkjet 3D printing (3DP), stereolithography (SLA), and 3D plotting. Finally, major applications areas are discussed, including electronic, aerospace, construction and biomedical applications, with detailed information on the design, fabrication and processing methods required in each case. - Provides a thorough, clear understanding of polymer preparation techniques and 3D and 4D printing processes, with a view to specific applications - Examines synthesis, formation methodology, the dispersion of fillers, characterization, properties, and performance of polymer nanocomposites - Explores the possibilities of 4D printing, covering the usage of stimuli responsive hydrogels and shape memory polymers

3D Bioprinting in Medicine

3D Bioprinting in Medicine PDF Author: Murat Guvendiren
Publisher: Springer
ISBN: 3030239063
Category : Medical
Languages : en
Pages : 217

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Book Description
This book provides current and emerging developments in bioprinting with respect to bioprinting technologies, bioinks, applications, and regulatory pathways. Topics covered include 3D bioprinting technologies, materials such as bioinks and bioink design, applications of bioprinting complex tissues, tissue and disease models, vasculature, and musculoskeletal tissue. The final chapter is devoted to clinical applications of bioprinting, including the safety, ethical, and regulatory aspects. This book serves as a go-to reference on bioprinting and is ideal for students, researchers and professionals, including those in academia, government, the medical industry, and healthcare.