Time domains of hypoxia adaptation: Evolutionary insights and applications, volume II

Time domains of hypoxia adaptation: Evolutionary insights and applications, volume II PDF Author: Tatum S. Simonson
Publisher: Frontiers Media SA
ISBN: 2832527930
Category : Science
Languages : en
Pages : 161

Get Book

Book Description

Time domains of hypoxia adaptation: Evolutionary insights and applications, volume II

Time domains of hypoxia adaptation: Evolutionary insights and applications, volume II PDF Author: Tatum S. Simonson
Publisher: Frontiers Media SA
ISBN: 2832527930
Category : Science
Languages : en
Pages : 161

Get Book

Book Description


Time Domains of Hypoxia Adaptation: Evolutionary Insights and Applications

Time Domains of Hypoxia Adaptation: Evolutionary Insights and Applications PDF Author: Tatum S. Simonson
Publisher: Frontiers Media SA
ISBN: 2889718468
Category : Science
Languages : en
Pages : 289

Get Book

Book Description


The Red Cell Life-Cycle From Erythropoiesis to Clearance

The Red Cell Life-Cycle From Erythropoiesis to Clearance PDF Author: Lars Kaestner
Publisher: Frontiers Media SA
ISBN: 2889457028
Category :
Languages : en
Pages : 238

Get Book

Book Description
The eBook ‘The red cell life-cycle from erythropoiesis to clearance’ continues the discussion of questions like: What are the changes associated with red blood cell maturation, adulthood and senescence? What are the determinants of red blood cell life span and clearance? What are the mechanisms in control of red blood cell mass in healthy humans and patients with various forms of anaemia? Can red blood cells be 'trained' to provide the body with more oxygen during endurance exercises? What are the markers of circulating red blood cell senescence and in cells during storage and transfusion? And what can be learned from various species that developed advanced adaptations to maintain oxygen delivery under stress conditions such as exercising to the limit, diving or living in anaerobic aquatic habitats or at high altitude? Within the approximately 120 days (or 40 in a mouse, or 150-170 in a horse) life span of 'healthy' red blood cells, many cellular properties change leading to aged mixed cell populations in the circulation. Red blood cells seem to be genetically terminated by the time they become red blood cells and the contributions of this eBook increase the understanding of this process. There are surprisingly versatile remodeling processes happening during the red blood cell life span. Numerous disorders are associated with the premature onset of the 'ageing process' of red blood cells. Furthermore, in vitro ageing and/or modifications as well as the slowing down of the modifications is an important issue in transfusion medicine. Many of the molecular mechanisms behind such effects are elucidated in this eBook.

Respiratory Muscle Training

Respiratory Muscle Training PDF Author: Alison McConnell
Publisher: Elsevier Health Sciences
ISBN: 0702054550
Category : Medical
Languages : en
Pages : 403

Get Book

Book Description
Respiratory Muscle Training: theory and practice is the world’s first book to provide an "everything-you-need-to-know" guide to respiratory muscle training (RMT). Authored by an internationally-acclaimed expert, it is an evidence-based resource, built upon current scientific knowledge, as well as experience at the cutting-edge of respiratory training in a wide range of settings. The aim of the book is to give readers: 1) an introduction to respiratory physiology and exercise physiology, as well as training theory; 2) an understanding of how disease affects the respiratory muscles and the mechanics of breathing; 3) an insight into the disease-specific, evidence-based benefits of RMT; 4) advice on the application of RMT as a standalone treatment, and as part of a rehabilitation programme; and finally, 5) guidance on the application of functional training techniques to RMT. The book is divided into two parts – theory and practice. Part I provides readers with access to the theoretical building blocks that support practice. It explores the evidence base for RMT as well as the different methods of training respiratory muscles and their respective efficacy. Part II guides the reader through the practical implementation of the most widely validated form of RMT, namely inspiratory muscle resistance training. Finally, over 150 "Functional" RMT exercises are described, which incorporate a stability and/or postural challenge – and address specific movements that provoke dyspnoea. Respiratory Muscle Training: theory and practice is supported by a dedicated website (www.physiobreathe.com), which provides access to the latest information on RMT, as well as video clips of all exercises described in the book. Purchasers will also receive a three-month free trial of the Physiotec software platform (via www.physiotec.ca), which allows clinicians to create bespoke training programmes (including video clips) that can be printed or emailed to patients. Introductory overviews of respiratory and exercise physiology, as well as training theory Comprehensive, up-to-date review of respiratory muscle function, breathing mechanics and RMT Analysis of the interaction between disease and respiratory mechanics, as well as their independent and combined influence upon exercise tolerance Analysis of the rationale and application of RMT to over 20 clinical conditions, e.g., COPD, heart failure, obesity, mechanical ventilation Evidence-based guidance on the implementation of inspiratory muscle resistance training Over 150 functional exercises that incorporate a breathing challenge www.physiobreathe.com - access up-to-date information, video clips of exercises and a three-month free trial of Physiotec’s RMT exercise module (via www.physiotec.ca)

The Hadal Zone

The Hadal Zone PDF Author: Alan Jamieson
Publisher: Cambridge University Press
ISBN: 1316060721
Category : Science
Languages : en
Pages : 397

Get Book

Book Description
The hadal zone represents one of the last great frontiers in marine science, accounting for 45% of the total ocean depth range. Despite very little research effort since the 1950s, the last ten years has seen a renaissance in hadal exploration, almost certainly as a result of technological advances that have made this otherwise largely inaccessible frontier, a viable subject for research. Providing an overview of the geology involved in trench formation, the hydrography and food supply, this book details all that is currently known about organisms at hadal depths and linkages to the better known abyssal and bathyal depths. New insights on how, where and what really survives and thrives in the deepest biozone are provided, allowing this region to be considered when dealing with sustainability and conservation issues in the marine environment.

Oxygen Sensing

Oxygen Sensing PDF Author:
Publisher: Elsevier
ISBN: 0080497195
Category : Science
Languages : en
Pages : 867

Get Book

Book Description
The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.

The Ocean and Cryosphere in a Changing Climate

The Ocean and Cryosphere in a Changing Climate PDF Author: Intergovernmental Panel on Climate Change (IPCC)
Publisher: Cambridge University Press
ISBN: 1009178466
Category : Science
Languages : en
Pages : 1807

Get Book

Book Description
The Intergovernmental Panel on Climate Change (IPCC) is the leading international body for assessing the science related to climate change. It provides policymakers with regular assessments of the scientific basis of human-induced climate change, its impacts and future risks, and options for adaptation and mitigation. This IPCC Special Report on the Ocean and Cryosphere in a Changing Climate is the most comprehensive and up-to-date assessment of the observed and projected changes to the ocean and cryosphere and their associated impacts and risks, with a focus on resilience, risk management response options, and adaptation measures, considering both their potential and limitations. It brings together knowledge on physical and biogeochemical changes, the interplay with ecosystem changes, and the implications for human communities. It serves policymakers, decision makers, stakeholders, and all interested parties with unbiased, up-to-date, policy-relevant information. This title is also available as Open Access on Cambridge Core.

Gene Expression and Regulation in Mammalian Cells - Transcription Toward the Establishment of Novel Therapeutics

Gene Expression and Regulation in Mammalian Cells - Transcription Toward the Establishment of Novel Therapeutics PDF Author:
Publisher:
ISBN: 9789535138686
Category :
Languages : en
Pages :

Get Book

Book Description


How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

Get Book

Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Human Adaptation to Spaceflight

Human Adaptation to Spaceflight PDF Author: Government Publishing Office
Publisher: Government Printing Office
ISBN: 9780160926297
Category :
Languages : en
Pages : 154

Get Book

Book Description
Human Adaptation to Spaceflight: The Role of Nutrition reflects a (brief) review of the history of and current state of knowledge about the role of nutrition in human space flight. We have attempted to morganize this from a more physiological point of view, and to highlight systems, and the nutrients that support them, rather than the other way around. We hope we have captured in this book the state of the field of study of the role of human nutrition in space flight, along with the work leading up to this state, and some guideposts for work remaining to be done and gaps that need to be filled. NOTE: NO FURTHER DISCOUNTS FOR ALREADY REDUCED SALE ITEMS.