Essential Zebrafish Methods: Genetics and Genomics

Essential Zebrafish Methods: Genetics and Genomics PDF Author: H. William Detrich III
Publisher: Academic Press
ISBN: 0123751616
Category : Science
Languages : en
Pages : 399

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Book Description
Due to its prolific reproduction and the external development of the transparent embryo, the zebrafish is the prime model for genetic and developmental studies, as well as research in genomics. While genetically distant from humans, nonetheless the vertebrate zebrafish has comparable organs and tissues that make it the model organism for study of vertebrate development.This book, one of two new volumes in the Reliable Lab Solutions series dealing with zebrafish, brings together a robust and up-to-date collection of time-tested methods presented by the world's leading scientists. Culled from previously published chapters in Methods in Cell Biology and updated by the original authors where relevant, it provides a comprehensive collection of protocols describing the most widely used techniques relevant to the study of zebrafish genetics and genomics. The methods in this volume were hand-selected by the editors, whose goal was to a provide a handy and cost-effective collection of fail-safe methods, tips, and "tricks of the trade" to both experienced researchers and more junior members in the lab. - Provides busy researchers a quick reference for time-tested methods and protocols that really work, updated where possible by the original authors - Gives pragmatic wisdom to the non-specialist from experts in the field with years of experience with trial and error

Essential Zebrafish Methods: Genetics and Genomics

Essential Zebrafish Methods: Genetics and Genomics PDF Author: H. William Detrich III
Publisher: Academic Press
ISBN: 0123751616
Category : Science
Languages : en
Pages : 399

Get Book Here

Book Description
Due to its prolific reproduction and the external development of the transparent embryo, the zebrafish is the prime model for genetic and developmental studies, as well as research in genomics. While genetically distant from humans, nonetheless the vertebrate zebrafish has comparable organs and tissues that make it the model organism for study of vertebrate development.This book, one of two new volumes in the Reliable Lab Solutions series dealing with zebrafish, brings together a robust and up-to-date collection of time-tested methods presented by the world's leading scientists. Culled from previously published chapters in Methods in Cell Biology and updated by the original authors where relevant, it provides a comprehensive collection of protocols describing the most widely used techniques relevant to the study of zebrafish genetics and genomics. The methods in this volume were hand-selected by the editors, whose goal was to a provide a handy and cost-effective collection of fail-safe methods, tips, and "tricks of the trade" to both experienced researchers and more junior members in the lab. - Provides busy researchers a quick reference for time-tested methods and protocols that really work, updated where possible by the original authors - Gives pragmatic wisdom to the non-specialist from experts in the field with years of experience with trial and error

The Zebrafish: Genetics and Genomics

The Zebrafish: Genetics and Genomics PDF Author:
Publisher: Academic Press
ISBN: 0080859585
Category : Science
Languages : en
Pages : 428

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Book Description
This is the second volume of a two-volume, comprehensive treatment of the methodologies used in researching the zebrafish, an emerging vertebrate model system. The text includes discussions on development, genetic methodologies, and model applications.Key Features* Details state-of-the-art zebrafish protocols in a single-source reference* Presents methods and reagents in user-friendly format* Delineates critical steps and pitfalls of he procedures* Illustrates techniques with full-color plates* Summarizes many new and interesting developmental mutants* Includes appendices with strain information and a compendium of zebrafish World Wide Web sites* Relevant to clinicians interested in vertebrate models of human congenital diseases

Fish Development and Genetics

Fish Development and Genetics PDF Author: Zhiyuan Gong
Publisher: World Scientific
ISBN: 9789812565761
Category : Technology & Engineering
Languages : en
Pages : 700

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Book Description
The zebrafish is the most important fish model in developmental andgenetic analyses. This book contains 19 review articles covering abroad spectrum of topics, from development to genetic tools. Thecontents range from early development, the role of maternal factorsand gastrulation, to tissue differentiation and organogenesis, such asdevelopment of the organizer, notochord, floor plate, nervous system, somites, muscle, skeleton and endoderm

Genomics in Aquaculture

Genomics in Aquaculture PDF Author: Simon A MacKenzie
Publisher: Academic Press
ISBN: 0128016906
Category : Technology & Engineering
Languages : en
Pages : 306

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Book Description
Genomics in Aquaculture is a concise, must-have reference that describes current advances within the field of genomics and their applications to aquaculture. Written in an accessible manner for anyone—non-specialists to experts alike—this book provides in-depth coverage of genomics spanning from genome sequencing, to transcriptomics and proteomics. It provides, for ease of learning, examples from key species most relevant to current intensive aquaculture practice. Its coverage of minority species that have a specific biological interest (e.g., Pleuronectiformes) makes this book useful for countries that are developing such species. It is a robust, practical resource that covers foundational, functional, and applied aspects of genomics in aquaculture, presenting the most current information in a field of research that is rapidly growing. - Provides the latest scientific methods and technologies to maximize efficiencies for healthy fish production, with summary tables for quick reference - Offers an extended glossary of technical and methodological terms to help readers better understand key biological concepts - Describes state-of-the-art technologies, such as transcriptomics and epigenomics, currently under development for future perspective of the field - Covers minority species that have a specific biological interest (e.g., Pleuronectiformes), making the book useful to countries developing such species

Zebrafish

Zebrafish PDF Author: Christiane Nusslein-Volhard
Publisher: Oxford University Press
ISBN: 9780199638086
Category : Science
Languages : en
Pages : 342

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Book Description
The zebrafish has become one of the most important model organisms to study biological processes within a living body. As a vertebrate that has many of the strengths of invertebrate model systems, it offers numerous advantages to researchers interested in many aspects of embryonic development, physiology and disease. This book not only provides a complete set of instructions that will allow researchers to establish the zebrafish in their laboratory. It also gives a broad overview of commonly used methods and a comprehensive collection of protocols describing the most powerful techniques.

Genome Editing in Neurosciences

Genome Editing in Neurosciences PDF Author: Rudolf Jaenisch
Publisher:
ISBN: 9781013268564
Category : Medical
Languages : en
Pages : 128

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Book Description
Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

The Zebrafish in Biomedical Research

The Zebrafish in Biomedical Research PDF Author: Samuel Cartner
Publisher: Academic Press
ISBN: 0128124326
Category : Science
Languages : en
Pages : 720

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Book Description
The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. - Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications - Includes the work of world-renowned authors - Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

The Zebrafish: Cellular and Developmental Biology, Part B

The Zebrafish: Cellular and Developmental Biology, Part B PDF Author:
Publisher: Academic Press
ISBN: 0123870372
Category : Technology & Engineering
Languages : en
Pages : 317

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Book Description
This volume of Methods in Cell Biology, the second of two parts on the subject of zebrafish, provides a comprehensive compendium of laboratory protocols and reviews covering all the new methods developed since 1999. - Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls - Illustrates many techiques in full-color - Summarizes the Zebrafish Genome Project

Long-Range Control of Gene Expression

Long-Range Control of Gene Expression PDF Author: Veronica van Heyningen
Publisher: Academic Press
ISBN: 0080877818
Category : Science
Languages : en
Pages : 415

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Book Description
Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer

Scientific Frontiers in Developmental Toxicology and Risk Assessment

Scientific Frontiers in Developmental Toxicology and Risk Assessment PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309070864
Category : Nature
Languages : en
Pages : 348

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Book Description
Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.