Tau Biology

Tau Biology PDF Author: Akihiko Takashima
Publisher: Springer Nature
ISBN: 9813293586
Category : Medical
Languages : en
Pages : 405

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Book Description
This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.

Tau Biology

Tau Biology PDF Author: Akihiko Takashima
Publisher: Springer Nature
ISBN: 9813293586
Category : Medical
Languages : en
Pages : 405

Get Book Here

Book Description
This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.

Neurology in Clinical Practice

Neurology in Clinical Practice PDF Author: Walter George Bradley
Publisher:
ISBN: 9780750674690
Category : Diagnosis
Languages : en
Pages : 1672

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Book Description
New edition, completely rewritten, with new chapters on endovascular surgery and mitochrondrial and ion channel disorders.

Research Advances in Rabies

Research Advances in Rabies PDF Author:
Publisher: Academic Press
ISBN: 0123870410
Category : Medical
Languages : en
Pages : 487

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Book Description
Volume 79 of Advances in Virus Research focuses on developments surrounding rabies, an ancient disease that remains a prominent public health problem for humans. This volume highlights important research advances extending from our understanding of how the rabies virus replicates and assembles to how the disease can be prevented and treated in humans and how rabies can be controlled in wildlife hosts. Experts in the field provide insightful and up-to-date chapters that summarize our current state of knowledge in diverse aspects of this very interesting and important viral disease. - Contributions from leading authorities and industry experts - Informs and updates on all the latest developments in the field

Inventing Ourselves

Inventing Ourselves PDF Author: Sarah-Jayne Blakemore
Publisher: PublicAffairs
ISBN: 1610397320
Category : Psychology
Languages : en
Pages : 234

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Book Description
A tour through the groundbreaking science behind the enigmatic, but crucial, brain developments of adolescence and how those translate into teenage behavior The brain creates every feeling, emotion, and desire we experience, and stores every one of our memories. And yet, until very recently, scientists believed our brains were fully developed from childhood on. Now, thanks to imaging technology that enables us to look inside the living human brain at all ages, we know that this isn't so. Professor Sarah-Jayne Blakemore, one of the world's leading researchers into adolescent neurology, explains precisely what is going on in the complex and fascinating brains of teenagers -- namely that the brain goes on developing and changing right through adolescence--with profound implications for the adults these young people will become. Drawing from cutting-edge research, including her own, Blakemore shows: How an adolescent brain differs from those of children and adults Why problem-free kids can turn into challenging teens What drives the excessive risk-taking and all-consuming relationships common among teenagers And why many mental illnesses -- depression, addiction, schizophrenia -- present during these formative years Blakemore's discoveries have transformed our understanding of the teenage mind, with consequences for law, education policy and practice, and, most of all, parents.

Pediatric Neurology

Pediatric Neurology PDF Author: Kenneth F. Swaiman
Publisher: Elsevier Health Sciences
ISBN: 0323033652
Category : Medical
Languages : en
Pages : 2535

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Book Description
This Gold Standard in clinical child neurology presents the entire specialty in the most comprehensive, authoritative, and clearly written fashion. Its clinical focus, along with relevant science, throughout is directed at both the experienced clinician and the physician in training. New editor, Dr. Ferriero brings expertise in neonatal neurology to the Fourth Edition. New chapters: Pathophysiology of Hypoxic Ischemic Encephalopathy, Congenital Disorders of Glycosylation, Pediatric Neurotransmitter Diseases, Neurophysiology of Epilepsy, Genetics of Epilepsy, Pediatric Neurorehabilitation Medicine, Neuropsychopharmacology, Pain and Palliative Care Management, Ethical Issues in Child Neurology

Textbook of Radiology And Imaging, Vol 2 - E-Book

Textbook of Radiology And Imaging, Vol 2 - E-Book PDF Author: Bharat Aggarwal
Publisher: Elsevier Health Sciences
ISBN: 8131259641
Category : Medical
Languages : en
Pages : 1574

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Book Description
This book is a classic guide for trainees and practitioners with a comprehensive overhaul, this book successfully bridges the gap between advancing technology, terminology, and the emergence of new diseases. With its all-encompassing approach, this book serves as the ultimate resource for radiology professionals, eliminating the need for multiple texts on various systems and recent updates. Trainees and practitioners alike will find immense value, as it caters to both skill enhancement and exam preparation for residents.For trainees, the book provides essential tools to elevate their expertise as it covers various topics. Meanwhile, community practitioners will greatly benefit from evidence-based guidelines and protocols presented in the book. - The new edition of Sutton retains the overall format, presentation style and comprehensive coverage of the previous editions. - Significant advances in imaging techniques and newer applications of different modalities have been incorporated in all sections - Radiology lexicons and updated classification systems for various diseases have been included. There is emphasis on differential diagnosis, appropriateness criteria and disease management. - Salient features have been highlighted as imaging pearls and teaching points. - New sections for Imaging Physics & Principles of Imaging, Emergency Radiology, Pediatric Radiology and Nuclear Medicine have been added to make the book more comprehensive. - Crucial topics on patient safety, quality assurance and structured reporting have been included to help radiologists become processes driven and ensure better patient care. - Chapters on Information technology and Artificial intelligence introduce residents to the digital environment that we live in and its impact on day to day practice. - A section on Interventional Radiology has been included to enable residents to get a deeper understanding of this subspeciality and explore its scope in modern medicine. - This edition of Sutton is aimed at presenting an exhaustive teaching and reference text for radiologists and other clinical specialists.

Awards, Honors, and Prizes

Awards, Honors, and Prizes PDF Author:
Publisher:
ISBN:
Category : Awards
Languages : en
Pages : 1624

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Book Description
Listing and description of 2228 awards, honors, and prizes given for outstanding achievement in the United States and Canada. Science, technology, and medicine are among the 28 broad fields covered. Main listing by organization, with address and annotation. Alphabetical index of awards, subject index of awards.

Youmans and Winn Neurological Surgery E-Book

Youmans and Winn Neurological Surgery E-Book PDF Author: H. Richard Winn
Publisher: Elsevier Health Sciences
ISBN: 0323674992
Category : Medical
Languages : en
Pages : 7439

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Book Description
Widely regarded as the definitive reference in the field, Youmans and Winn Neurological Surgery offers unparalleled, multimedia coverage of the entirety of this complex specialty. Fully updated to reflect recent advances in the basic and clinical neurosciences, the 8th Edition covers everything you need to know about functional and restorative neurosurgery, deep brain stimulation, stem cell biology, radiological and nuclear imaging, and neuro-oncology, as well as minimally invasive surgeries in spine and peripheral nerve surgery, and endoscopic and other approaches for cranial procedures and cerebrovascular diseases. In four comprehensive volumes, Dr. H. Richard Winn and his expert team of editors and authors provide updated content, a significantly expanded video library, and hundreds of new video lectures that help you master new procedures, new technologies, and essential anatomic knowledge in neurosurgery. - Discusses current topics such as diffusion tensor imaging, brain and spine robotic surgery, augmented reality as an aid in neurosurgery, AI and big data in neurosurgery, and neuroimaging in stereotactic functional neurosurgery. - 55 new chapters provide cutting-edge information on Surgical Anatomy of the Spine, Precision Medicine in Neurosurgery, The Geriatric Patient, Neuroanesthesia During Pregnancy, Laser Interstitial Thermal Therapy for Epilepsy, Fetal Surgery for Myelomeningocele, Rehabilitation of Acute Spinal Cord Injury, Surgical Considerations for Patients with Polytrauma, Endovascular Approaches to Intracranial Aneurysms, and much more. - Hundreds of all-new video lectures clarify key concepts in techniques, cases, and surgical management and evaluation. Notable lecture videos include multiple videos on Thalamotomy for Focal Hand Dystonia and a video to accompany a new chapter on the Basic Science of Brain Metastases. - An extensive video library contains stunning anatomy videos and videos demonstrating intraoperative procedures with more than 800 videos in all. - Each clinical section contains chapters on technology specific to a clinical area. - Each section contains a chapter providing an overview from experienced Section Editors, including a report on ongoing controversies within that subspecialty. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Textbook of Contemporary Neurosurgery (Volumes 1 & 2)

Textbook of Contemporary Neurosurgery (Volumes 1 & 2) PDF Author: Vincent A Thamburaj
Publisher: JP Medical Ltd
ISBN: 9350252392
Category : Medical
Languages : en
Pages : 1882

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Book Description
This two volume set is a comprehensive guide to neurosurgery. Each section covers neurological disorders in different parts of the body, beginning with an introduction and ending with key practice points for quick review, integrating theory and practice. Genetics, ethics and physiotherapy are also discussed. With contributions from recognised specialists in the USA and Europe, this practical manual includes more than 1000 images and illustrations to assist learning and understanding. Key Features Comprehensive two volume set giving complete review of field of neurosurgery Covers numerous neurological disorders in different parts of the body Each section feature key practice points for quick review Integrates theory and practice More than 1000 images and illustrations Contributions from US and European specialists

Performance and Participation Outcomes for Individuals With Neurological Conditions

Performance and Participation Outcomes for Individuals With Neurological Conditions PDF Author: Naomi Josman
Publisher: Frontiers Media SA
ISBN: 2889661490
Category : Medical
Languages : en
Pages : 160

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.