The Technology of Discovery

The Technology of Discovery PDF Author: David Friedrich Woerner
Publisher: John Wiley & Sons
ISBN: 1119811368
Category : Science
Languages : en
Pages : 340

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Book Description
The Technology of Discovery Incisive discussions of a critical mission-enabling technology for deep space missions In The Technology of Discovery: Radioisotope Thermoelectric Generators and Thermoelectric Technologies for Space Exploration, distinguished JPL engineer and manager David Woerner delivers an insightful discussion of how radioisotope thermoelectric generators (RTGs) are used in the exploration of space. It also explores their history, function, their market potential, and the governmental forces that drive their production and design. Finally, it presents key technologies incorporated in RTGs and their potential for future missions and design innovation. The author provides a clear and understandable treatment of the subject, ranging from straightforward overviews of the technology to complex discussions of the field of thermoelectrics. Included is also background on NASA’s decision to resurrect the GPHS-RTG and discussion of the future of commercialization of nuclear space missions. Readers will also find: A thorough introduction to RTGs, as well as their invention, history, and evolution Comprehensive explorations of the contributions made by RTGs to US space exploration Practical discussions of the evolution, selection, and production of RPS fuels In-depth examinations of technologies and generators currently in development, including skutterudite thermoelectrics for an enhanced MMRTG Perfect for space explorers, aerospace engineers, managers, and scientists, The Technology of Discovery will also earn a place in the libraries of NASA archivists and other historians.

The Technology of Discovery

The Technology of Discovery PDF Author: David Friedrich Woerner
Publisher: John Wiley & Sons
ISBN: 1119811368
Category : Science
Languages : en
Pages : 340

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Book Description
The Technology of Discovery Incisive discussions of a critical mission-enabling technology for deep space missions In The Technology of Discovery: Radioisotope Thermoelectric Generators and Thermoelectric Technologies for Space Exploration, distinguished JPL engineer and manager David Woerner delivers an insightful discussion of how radioisotope thermoelectric generators (RTGs) are used in the exploration of space. It also explores their history, function, their market potential, and the governmental forces that drive their production and design. Finally, it presents key technologies incorporated in RTGs and their potential for future missions and design innovation. The author provides a clear and understandable treatment of the subject, ranging from straightforward overviews of the technology to complex discussions of the field of thermoelectrics. Included is also background on NASA’s decision to resurrect the GPHS-RTG and discussion of the future of commercialization of nuclear space missions. Readers will also find: A thorough introduction to RTGs, as well as their invention, history, and evolution Comprehensive explorations of the contributions made by RTGs to US space exploration Practical discussions of the evolution, selection, and production of RPS fuels In-depth examinations of technologies and generators currently in development, including skutterudite thermoelectrics for an enhanced MMRTG Perfect for space explorers, aerospace engineers, managers, and scientists, The Technology of Discovery will also earn a place in the libraries of NASA archivists and other historians.

Discovery and Classification in Astronomy

Discovery and Classification in Astronomy PDF Author: Steven J. Dick
Publisher: Cambridge University Press
ISBN: 1107033616
Category : Nature
Languages : en
Pages : 475

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Book Description
This book shows that astronomical discovery is a complex and ongoing process comprising various stages of research, interpretation and understanding.

Thinking Through Technology

Thinking Through Technology PDF Author: Carl Mitcham
Publisher: University of Chicago Press
ISBN: 0226531988
Category : Philosophy
Languages : en
Pages : 410

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Book Description
This introduction to the philosophy of technology discusses its sources and uses. Tracing the changing meaning of "technology" from ancient times to the modern day, it identifies two important traditions of critical analysis of technology: the engineering approach and the humanities approach.

Knowledge and the Wealth of Nations: A Story of Economic Discovery

Knowledge and the Wealth of Nations: A Story of Economic Discovery PDF Author: David Warsh
Publisher: W. W. Norton & Company
ISBN: 0393066363
Category : Business & Economics
Languages : en
Pages : 448

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Book Description
"What The Double Helix did for biology, David Warsh's Knowledge and the Wealth of Nations does for economics." —Boston Globe A stimulating and inviting tour of modern economics centered on the story of one of its most important breakthroughs. In 1980, the twenty-four-year-old graduate student Paul Romer tackled one of the oldest puzzles in economics. Eight years later he solved it. This book tells the story of what has come to be called the new growth theory: the paradox identified by Adam Smith more than two hundred years earlier, its disappearance and occasional resurfacing in the nineteenth century, the development of new technical tools in the twentieth century, and finally the student who could see further than his teachers. Fascinating in its own right, new growth theory helps to explain dominant first-mover firms like IBM or Microsoft, underscores the value of intellectual property, and provides essential advice to those concerned with the expansion of the economy. Like James Gleick's Chaos or Brian Greene's The Elegant Universe, this revealing book takes us to the frontlines of scientific research; not since Robert Heilbroner's classic work The Worldly Philosophers have we had as attractive a glimpse of the essential science of economics.

Scientific Discovery

Scientific Discovery PDF Author: Aharon Kantorovich
Publisher: State University of New York Press
ISBN: 1438408331
Category : Philosophy
Languages : en
Pages : 298

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Book Description
Kantorovich analyzes the notion of discovery. He views the process as inference and questions whether there is logic or method to discovery. He provides an alternative perspective on scientific discovery that explains the difficulties in finding a satisfactory method of discovery. Within the framework of evolutionary epistemology, discovery is treated as a phenomenon in its own right having psychological and social dimensions. Science is viewed as a continuation of the evolutionary process whereby creative discovery plays a role similar to blind mutation in biological evolution. From this perspective, serendipity and tinkering are key notions in understanding the creative process.

Collaborative Innovation in Drug Discovery

Collaborative Innovation in Drug Discovery PDF Author: Rathnam Chaguturu
Publisher: John Wiley & Sons
ISBN: 111877812X
Category : Medical
Languages : en
Pages : 768

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Book Description
Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent need for novel therapies cannot stem the skyrocketing costs and plummeting productivity plaguing R&D, and many key products are facing patent expiration. Dr. Rathnam Chaguturu presents a case for collaboration between the pharmaceutical industry and academia that could reverse the industry's decline. Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships provides insight into the potential synergy of basing R&D in academia while leaving drug companies to turn hits into marketable products. As Founder and CEO of iDDPartners, focused on pharmaceutical innovation, Founding president of the International Chemical Biology Society, and Senior Director-Discovery Sciences, SRI International, Dr. Chaguturu has assembled a panel of experts from around the world to weigh in on issues that affect the two driving forces in medical advancement. Gain global perspectives on the benefits and potential issues surrounding collaborative innovation Discover how industries can come together to prevent another "Pharma Cliff" Learn how nonprofits are becoming the driving force behind innovation Read case studies of specific academia-pharma partnerships for real-life examples of successful collaboration Explore government initiatives that help foster cooperation between industry and academia Dr. Chaguturu’s thirty-five years of experience in academia and industry, managing new lead discovery projects and forging collaborative partnerships with academia, disease foundations, nonprofits, and government agencies lend him an informative perspective into the issues facing pharmaceutical progress. In Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships, he and his expert team provide insight into the various nuances of the debate.

Discovery

Discovery PDF Author:
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 376

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Book Description


The Theory of Industrial Organization

The Theory of Industrial Organization PDF Author: Jean Tirole
Publisher: MIT Press
ISBN: 0262200716
Category : Business & Economics
Languages : en
Pages : 1482

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Book Description
The Theory of Industrial Organization is the first primary text to treat the new industrial organization at the advanced-undergraduate and graduate level. Rigorously analytical and filled with exercises coded to indicate level of difficulty, it provides a unified and modern treatment of the field with accessible models that are simplified to highlight robust economic ideas while working at an intuitive level. To aid students at different levels, each chapter is divided into a main text and supplementary section containing more advanced material. Each chapter opens with elementary models and builds on this base to incorporate current research in a coherent synthesis. Tirole begins with a background discussion of the theory of the firm. In Part I he develops the modern theory of monopoly, addressing single product and multi product pricing, static and intertemporal price discrimination, quality choice, reputation, and vertical restraints. In Part II, Tirole takes up strategic interaction between firms, starting with a novel treatment of the Bertrand-Cournot interdependent pricing problem. He studies how capacity constraints, repeated interaction, product positioning, advertising, and asymmetric information affect competition or tacit collusion. He then develops topics having to do with long term competition, including barriers to entry, contestability, exit, and research and development. He concludes with a "game theory user's manual" and a section of review exercises. Important Notice: The digital edition of this book is missing some of the images found in the physical edition.

Target Discovery and Validation

Target Discovery and Validation PDF Author: Alleyn T. Plowright
Publisher: John Wiley & Sons
ISBN: 3527818251
Category : Medical
Languages : en
Pages : 399

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Book Description
The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.

The Process of New Drug Discovery and Development

The Process of New Drug Discovery and Development PDF Author: G. Smith Charles
Publisher: CRC Press
ISBN: 9780849342110
Category : Medical
Languages : en
Pages : 166

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Book Description
The Process of New Drug Discovery and Development presents a practical methodology for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It includes detailed discussions regarding the research process and presents critiques of the governmental regulatory aspects of pharmaceutical research. The author also addresses the controversy surrounding the use of animals in biomedical research and provides current information regarding the field of biotechnology, international drug research, and registration activities. The Process of New Drug Discovery and Development is an excellent "how to" text for pharmaceutical researchers, oncologists, biochemists, experimental biologists, and others involved in new drug research and development.