Tachykinins

Tachykinins PDF Author: Peter Holzer
Publisher: Springer Science & Business Media
ISBN: 3642188915
Category : Medical
Languages : en
Pages : 574

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Book Description
The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered.

Tachykinins

Tachykinins PDF Author: Peter Holzer
Publisher: Springer Science & Business Media
ISBN: 3642188915
Category : Medical
Languages : en
Pages : 574

Get Book Here

Book Description
The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered.

Cough

Cough PDF Author: Kian Fan Chung
Publisher: John Wiley & Sons
ISBN: 0470755032
Category : Medical
Languages : en
Pages : 320

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Book Description
Cough is the most familiar symptom of respiratory disease, and a problem which general practitioners must deal with on a daily basis. This timely volume draws together a wealth of recent research into the mechanisms, pharmacology and therapies for cough, and places these in clinical context. The text incorporates guidelines on the most common causes of cough, discusses treatments and pitfalls in management, summarizes current research on physiology, pharmacology and treatment of cough, and gives practical advice on diagnosis and management issues for the clinician. Cough: Causes, Mechanisms and Therapy is the most comprehensive, up-to-date account of the subject. It will update clinical and basic medical scientists, and promote future research. Readers are encouraged to implement the clinical implications of the discussion into routine practice. This volume will appeal to all those involved in the treatment of respiratory disease, particularly those in hospital respiratory units, and will also be of use to interested general practitioners.

Pharmacology and Therapeutics of Cough

Pharmacology and Therapeutics of Cough PDF Author: K. Fan Chung
Publisher: Springer Science & Business Media
ISBN: 3540798420
Category : Medical
Languages : en
Pages : 380

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Book Description
The last decade or so has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the phar- cological receptors on their membranes, the brainstem organization of the ‘cough centre’, and the involvement of the cerebral cortex in the sensations and the vol- tary control of cough. With the exception of the last of these, nearly all the studies have been on experimental animals rather than humans, for obvious reasons. One group of experimental studies has particular relevance to human patients, and that is the demonstration of the sensitization of cough pathways both in the periphery and in the brainstem. Similar sensitizations have been shown for patients with chronic cough or who have been exposed to pollutants, and it is reasonable to suppose that this is the basis of their cough and that the underlying mechanisms are generally similar in humans and other species. Important advances are also being made in clinical cough research. For the three main causes of clinical cough, asthma, post-nasal drip syndrome, and gast- oesophageal re?ux disease, we are beginning to understand the pathological processes involved. There remains a diagnostically obdurate group of idiopathic chronic coughers, but even for them approaches are being devised to clarify und- lying mechanisms and to establish diagnoses. Perhaps surprisingly, the ?eld in which there has been the least spectacular - vance is the therapy of cough.

Handbook of Neuroendocrinology

Handbook of Neuroendocrinology PDF Author: George Fink
Publisher: Academic Press
ISBN: 0123750970
Category : Medical
Languages : en
Pages : 895

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Book Description
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Substance P in the Nervous System

Substance P in the Nervous System PDF Author: Ruth Porter
Publisher: Financial Times/Prentice Hall
ISBN:
Category : Medical
Languages : en
Pages : 368

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Book Description


Handbook of Neurochemistry and Molecular Neurobiology

Handbook of Neurochemistry and Molecular Neurobiology PDF Author: Ramon Lim
Publisher: Springer Science & Business Media
ISBN: 0387303480
Category : Medical
Languages : en
Pages : 691

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Book Description
"The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.

Biological Inhibitors

Biological Inhibitors PDF Author: M. Iqbal Choudhary
Publisher: CRC Press
ISBN: 1000141314
Category : Science
Languages : en
Pages : 396

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Book Description
This book, a part of the series Studies in Medicinal Chemistry, details the biological inhibitors that reflect drug discovery in treating human diseases, including cardiovascular, nervous, inflammatory, hormonal and metabolic processes. Compounds for fungal diseases and HIV/AIDS are also covered.

Substance P and Related Peptides

Substance P and Related Peptides PDF Author: Susan E. Leeman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 520

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Book Description


Behavioral Genetics of the Fly (Drosophila Melanogaster)

Behavioral Genetics of the Fly (Drosophila Melanogaster) PDF Author: Josh Dubnau
Publisher: Cambridge University Press
ISBN: 1107009030
Category : Medical
Languages : en
Pages : 309

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Book Description
A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.

The Evolution of Neuropeptides – A Stroll Through the Animal Kingdom: Updates from the Ottawa 2019 ICCPB Symposium and Beyond

The Evolution of Neuropeptides – A Stroll Through the Animal Kingdom: Updates from the Ottawa 2019 ICCPB Symposium and Beyond PDF Author: Klaus H. Hoffmann
Publisher: Frontiers Media SA
ISBN: 2889660176
Category : Medical
Languages : en
Pages : 163

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.