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Author: Rejean Couture
Publisher: Springer Science & Business Media
ISBN: 1461246725
Category : Nature
Languages : en
Pages : 409
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Book Description
Sarajevo was the site of the first international meeting on substance P. It was held in 1961, thirty years after the first report of the discovery of substance P by Von Euler and Gaddum. The proceedings which follow are from a symposium held twenty-five years after the first meeting. These twenty-five years have seen a vast expansion in this field ofresearch. This family of peptides now includes a number of different mammalian and non-mammalian related peptides. Beyond the early physiological and pharmacological studies, there is important new information coming from the full spectrum of disciplines in the basic medical sciences, including molecular biology, which has given us important insights into the biosynthetic mechanisms of origin of these peptides. Montreal was chosen as the site for the 1986 meeting. The name given to it was "Sub stance P & Neurokinins-Montreal '86." This name was modelled after the one held in Dublin in 1982, but neurokinins were added to acknowledge the broader family of peptides. The meeting was held as a Satellite Symposium of the XXX International Congress of the International Union of Physiological Sciences in Vancouver. The venue was McGill University, and the dates were 21-23 July, 1986.
Author: Rejean Couture
Publisher: Springer Science & Business Media
ISBN: 1461246725
Category : Nature
Languages : en
Pages : 409
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Book Description
Sarajevo was the site of the first international meeting on substance P. It was held in 1961, thirty years after the first report of the discovery of substance P by Von Euler and Gaddum. The proceedings which follow are from a symposium held twenty-five years after the first meeting. These twenty-five years have seen a vast expansion in this field ofresearch. This family of peptides now includes a number of different mammalian and non-mammalian related peptides. Beyond the early physiological and pharmacological studies, there is important new information coming from the full spectrum of disciplines in the basic medical sciences, including molecular biology, which has given us important insights into the biosynthetic mechanisms of origin of these peptides. Montreal was chosen as the site for the 1986 meeting. The name given to it was "Sub stance P & Neurokinins-Montreal '86." This name was modelled after the one held in Dublin in 1982, but neurokinins were added to acknowledge the broader family of peptides. The meeting was held as a Satellite Symposium of the XXX International Congress of the International Union of Physiological Sciences in Vancouver. The venue was McGill University, and the dates were 21-23 July, 1986.
Author: Peter Holzer
Publisher: Springer Science & Business Media
ISBN: 3642188915
Category : Medical
Languages : en
Pages : 574
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Book Description
The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered.
Author: George Fink
Publisher: Academic Press
ISBN: 0123750970
Category : Medical
Languages : en
Pages : 895
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Book Description
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Author: Susan E. Leeman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 520
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Book Description
Author: Kian Fan Chung
Publisher: John Wiley & Sons
ISBN: 0470755032
Category : Medical
Languages : en
Pages : 320
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Book Description
Cough is the most familiar symptom of respiratory disease, and a problem which general practitioners must deal with on a daily basis. This timely volume draws together a wealth of recent research into the mechanisms, pharmacology and therapies for cough, and places these in clinical context. The text incorporates guidelines on the most common causes of cough, discusses treatments and pitfalls in management, summarizes current research on physiology, pharmacology and treatment of cough, and gives practical advice on diagnosis and management issues for the clinician. Cough: Causes, Mechanisms and Therapy is the most comprehensive, up-to-date account of the subject. It will update clinical and basic medical scientists, and promote future research. Readers are encouraged to implement the clinical implications of the discussion into routine practice. This volume will appeal to all those involved in the treatment of respiratory disease, particularly those in hospital respiratory units, and will also be of use to interested general practitioners.
Author: Shozo Kito
Publisher: Springer Science & Business Media
ISBN: 1468459074
Category : Medical
Languages : en
Pages : 489
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Book Description
The Third International Symposium on Neurotransmitter Receptors was held in Hiroshima at a time when the entire field of neurotransmitter receptors in the brain is progressing at an unprecedented pace. The sym posium also marked my retirement as Professor and Chairman of the Third Department of Internal Medicine, Hiroshima University School of Medicine, and a new beginning as a Professor of the University of the Air. The symposium was remarkably successful, and there were enthusiastic responses from scientists allover the world, proving that the meeting was timely. The selected papers contained in this volume constitute a state of-the-art survey of the most advanced aspects of neurotransmitter recep tor mechanisms in the brain. lowe thanks for the great success of the symposium to Prof. Richard Olsen of UCLA, Prof. Tomio Segawa of Hiroshima University, Prof. Kinya Kuriyama of Kyoto Prefectural University of Medicine, and Prof. Masaya Tohyama of Osaka University. I express my sincere gratitude to many friends for making this publication possible. I especially thank Dr. Rie Miyoshi, whose devoted efforts as secretary-general were vital to the success of the symposium. Dr. Miyoshi is currently an instructor in the Department of Pharmacology at Tokyo Women's Medical College. I would also like to acknowledge the excellent secretarial work of Misses Ritsuko Sato and Yuko Wakita.
Author: M. Iqbal Choudhary
Publisher: CRC Press
ISBN: 1000141314
Category : Science
Languages : en
Pages : 396
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Book Description
This book, a part of the series Studies in Medicinal Chemistry, details the biological inhibitors that reflect drug discovery in treating human diseases, including cardiovascular, nervous, inflammatory, hormonal and metabolic processes. Compounds for fungal diseases and HIV/AIDS are also covered.
Author: K. Fan Chung
Publisher: Springer Science & Business Media
ISBN: 3540798420
Category : Medical
Languages : en
Pages : 380
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Book Description
The last decade or so has seen remarkable advances in our knowledge of cough. This applies especially to its basic mechanisms: the types of airway sensors, the phar- cological receptors on their membranes, the brainstem organization of the ‘cough centre’, and the involvement of the cerebral cortex in the sensations and the vol- tary control of cough. With the exception of the last of these, nearly all the studies have been on experimental animals rather than humans, for obvious reasons. One group of experimental studies has particular relevance to human patients, and that is the demonstration of the sensitization of cough pathways both in the periphery and in the brainstem. Similar sensitizations have been shown for patients with chronic cough or who have been exposed to pollutants, and it is reasonable to suppose that this is the basis of their cough and that the underlying mechanisms are generally similar in humans and other species. Important advances are also being made in clinical cough research. For the three main causes of clinical cough, asthma, post-nasal drip syndrome, and gast- oesophageal re?ux disease, we are beginning to understand the pathological processes involved. There remains a diagnostically obdurate group of idiopathic chronic coughers, but even for them approaches are being devised to clarify und- lying mechanisms and to establish diagnoses. Perhaps surprisingly, the ?eld in which there has been the least spectacular - vance is the therapy of cough.
Author: Stephen H. Buck
Publisher: Springer Science & Business Media
ISBN: 1461203015
Category : Medical
Languages : en
Pages : 637
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Book Description
Offers a state-of-the-art review by international experts on all aspects of tachykinin receptors, including neuropeptide/peptide and G-protein-linked receptors in general. It covers the physiology, pharmacology, biochemistry, and molecular biology of these receptors from both clinical and basic research points of view. Topics treated by the distinguished contributors include the characterization of tachykinin receptors, the mechanisms of tachykinin receptor action, a reflection on future prospects, and a historical consideration of tachykinin research.
Author: Josh Dubnau
Publisher: Cambridge University Press
ISBN: 1107009030
Category : Medical
Languages : en
Pages : 309
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Book Description
A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.
