The Six-[pi]-electrocyclization of 1-azatrienes to 1,2-dihydropyridines and the Synthesis of 18-substituted Vitamin D3 Analogs

The Six-[pi]-electrocyclization of 1-azatrienes to 1,2-dihydropyridines and the Synthesis of 18-substituted Vitamin D3 Analogs PDF Author: David Forbes Maynard
Publisher:
ISBN:
Category : Aldehydes
Languages : en
Pages : 850

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The Six-[pi]-electrocyclization of 1-azatrienes to 1,2-dihydropyridines and the Synthesis of 18-substituted Vitamin D3 Analogs

The Six-[pi]-electrocyclization of 1-azatrienes to 1,2-dihydropyridines and the Synthesis of 18-substituted Vitamin D3 Analogs PDF Author: David Forbes Maynard
Publisher:
ISBN:
Category : Aldehydes
Languages : en
Pages : 850

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Inventing Reactions

Inventing Reactions PDF Author: Lukas J. Gooßen
Publisher: Springer
ISBN: 3642342868
Category : Science
Languages : en
Pages : 345

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Book Description
Barry Trost: Transition metal catalyzed allylic alkylation.- Jeffrey W. Bode: Reinventing Amide Bond Formation.- Naoto Chatani and Mamoru Tobisu: Catalytic Transformations Involving the Cleavage of C-OMe Bonds.- Gregory L. Beutner and Scott E. Denmark: The Interplay of Invention, Observation and Discovery in the Development of Lewis Base Activation of Lewis Acids for Catalytic Enantioselective Synthesis.- David R. Stuart and Keith Fagnou: The Discovery and Development of a Palladium(II)-Catalyzed Oxidative Cross-Coupling of Two Unactivated Arenes.- Lukas Gooßen and Käthe Gooßen: Decarboxylative Cross-Coupling Reactions.- A. Stephen K. Hashmi: Gold-Catalyzed Organic Reactions.- Ben List: Developing Catalytic Asymmetric Acetalizations.- Steven M. Bischof, Brian G. Hashiguchi, Michael M. Konnick, and Roy A. Periana: The De NovoDesign of CH Bond Hydroxylation Catalysts.- Benoit Cardinal-David, Karl A. Scheidt: Carbene Catalysis: Beyond the Benzoin and Stetter Reactions.- Kenso Soai and Tsuneomi Kawasaki: Asymmetric autocatalysis of pyrimidyl alkanol.- Douglas C. Behenna and Brian M. Stoltz: Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents. Hisashi Yamamoto: Acid Catalysis in Organic Synthesis.

Advanced Organic Chemistry

Advanced Organic Chemistry PDF Author: Reinhard Bruckner
Publisher: Academic Press
ISBN: 9780121381103
Category : Science
Languages : en
Pages : 308

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Book Description
A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.

Carotenoids, Volume 3: Biosynthesis and Metabolism

Carotenoids, Volume 3: Biosynthesis and Metabolism PDF Author: G. Britton
Publisher: Birkhäuser
ISBN:
Category : Medical
Languages : en
Pages : 440

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Book Description
Volume 3 of the Carotenoids series moves into the area of biochemistry & biology, concentrating on how the carotenoid molecules are formed in nature & utilized or modified by living organisms. Animals cannot biosynthesize carotenoids de novo. Dietary carotenoids provide most of the vitamin A that is vital for health & development in humans & other mammals. The formation of vitamin A & the absorption, transport & deposition of carotenoids in tissues in mammals are described, followed by a detailed account of the diverse metabolic reactions by which dietary carotenoids undergo structural & stereochemical changes in birds, fish & invertebrate animals. The relevance of carotenoids for use as markers to trace food chains is also discussed. In keeping with the philosophy of the carotenoid series guidance on the application of some of the most important experimental procedures for studies of biosynthesis & metabolism are given in the final chapter. The information presented & analyzed by expert authors in this volume will serve as a useful reference source, & give valuable guidance on practical strategies & procedures, as a foundation for the exciting advances that can be expected in carotenoid biosynthesis & metabolism in the next few years.

Carotenoids, Vol. 4: Natural Functions

Carotenoids, Vol. 4: Natural Functions PDF Author: George Britton
Publisher: Springer Science & Business Media
ISBN: 3764374993
Category : Science
Languages : en
Pages : 400

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Book Description
The Carotenoids book series provides an introduction to the fundamental chemistry, detailed accounts of the basic methods used in carotenoid research, and critical discussions of the biochemistry, functions and applications of carotenoids. Part 1 discusses the fundamental properties on which the biological functions and effects of carotenoids depend. Part 2 describes important natural functions of carotenoids in all kinds of living organisms.

Transition Metal Catalyzed Enantioselective Allylic Substitution in Organic Synthesis

Transition Metal Catalyzed Enantioselective Allylic Substitution in Organic Synthesis PDF Author: Uli Kazmaier
Publisher: Springer Science & Business Media
ISBN: 3642227481
Category : Science
Languages : en
Pages : 354

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Book Description
Giovanni Poli, Guillaume Prestat, Frédéric Liron, Claire Kammerer-Pentier: Selectivity in Palladium Catalyzed Allylic Substitution.- Jonatan Kleimark and Per-Ola Norrby: Computational Insights into Palladium-mediated Allylic Substitution Reactions.- Ludovic Milhau, Patrick J. Guiry: Palladium-catalyzed enantioselective allylic substitution.- Wen-Bo Liu, Ji-Bao Xia, Shu-Li You: Iridium-Catalyzed Asymmetric Allylic Substitutions.- Christina Moberg: Molybdenum- and Tungsten-Catalyzed Enantioselective Allylic Substitutions.- Jean-Baptiste Langlois, Alexandre Alexakis: Copper-catalyzed enantioselective allylic substitution.- Jeanne-Marie Begouin, Johannes E. M. N. Klein, Daniel Weickmann, B. Plietker: Allylic Substitutions Catalyzed by Miscellaneous Metals.- Barry M. Trost, Matthew L. Crawley: Enantioselective Allylic Substitutions in Natural Product Synthesis.

Retinoid Therapy

Retinoid Therapy PDF Author: W.J. Cunliffe
Publisher: Springer Science & Business Media
ISBN: 9401163499
Category : Medical
Languages : en
Pages : 312

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Book Description
The impact of the retinoids in clinical practice has primarily been in dermatology. When Dr Werner Bollag began his basic research and screening programme in the early 1960's, the expectation was that the retinoids would have a major impact on oncology. However, the laboratory and clinical experiences of Bollag and his colleagues in Switzerland, Stuttgen and Orfanos in Germany, led to publications on both etretinates (Tigason) and isotretinoin (Roaccutane) in the years between 1972 and 1976 in the field of dermatology. In fact the first symposium on retinoid research held in Berlin in 1981 was almost entirely dermatological. A year later a retinoid workshop in Iowa was designed to provide a forum for dermatolog ists from the USA involved in specific protocols investigating oral retinoids. In the UK, research into the retinoids began rather later than in Continental Europe or in the USA, although Tigason was first marketed here. It was felt in late 1982 that as many dermatologists had relatively little experience with these compounds it would be appropriate to hold an International Symposium on retinoid therapy in the UK. Thus on 16-18 May 1983 in London, 37 speakers from 11 countries addressed an audience of 300, aminly UK, dermatologists. The scientific organizing committee consisted of but two persons Dr William Cunliffe of Leeds General Infirmary, representing the European Society of Dermatolo gical Research, and myself from Roche Clinical Research. The Symposium was held under the auspices of the ESDR and of Roche Products Limited.

Selectivity in Organic Synthesis

Selectivity in Organic Synthesis PDF Author: Robert S. Ward
Publisher: John Wiley & Sons
ISBN: 0471987794
Category : Science
Languages : en
Pages : 197

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Book Description
Selectivity is an increasingly important part of organic synthesis. The whole basis of organic chemistry, and especially organic synthesis, depends upon the selectivity which can be achieved in organic reactions. This concise textbook describes the strategies which can be adopted to improve selectivity, and the reactions which have been specially designed to afford high selectivity. The aim is to illustrate the range of processes to which these principles can be applied and the high degree of selectivity which can be achieved. Selectivity in Organic Synthesis aims to provide a solid introduction to this subject, focusing on the key areas and applications.

Applications of MO Theory in Organic Chemistry

Applications of MO Theory in Organic Chemistry PDF Author: I.G. Csizmadia
Publisher: Elsevier
ISBN: 148316392X
Category : Science
Languages : en
Pages : 641

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Book Description
Applications of MO Theory in Organic Chemistry is a documentation of the proceedings of the First Theoretical Organic Chemistry meeting. This text is divided into five sections. Section A contains contributions ranging from the stereochemistry of stable molecules, radicals, and molecular ions, through hydrogen bonding and ion solvation to mathematical analyses of energy hypersurfaces. Section B deals with theoretical studies of organic reactions, including basecatalyzed hydrolysis, protonation, epoxidation, and electrophilic addition to double and triple bonds. Section C consists of topics starting with a qualitative configuration interaction treatment of thermal and photochemical organic reactions, followed by ab initio treatments of photochemical intermediates and a consideration of the role of Rydberg and valence-shell states in photochemistry. Section D provides analyses of methods for the determination and characterization of localized MO and discussions of correlated electron pair functions. Section E covers a very wide range from the application of statistical physics to the treatment of molecular interactions with their environments to a challenge to theoretical organic chemists in the field of natural products, and an introduction to information theory in organic chemistry. This book is a good source of information for students and researchers conducting study on the many areas in theoretical organic chemistry.

Science of Synthesis

Science of Synthesis PDF Author: D. Bellus
Publisher:
ISBN: 9783131187215
Category : Organic compounds
Languages : en
Pages :

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Book Description