Author: Alexander Theodore Shulgin
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 672
Book Description
From the man who has done more research into,Ecstacy than any other chemist, author of the,best-selling Phenethylamines I Have Known and,Tyroptomines I Have Known, this is a comprehensive,reference work on isoquinolines found in plants.,Found in cactii and poppies among other plants,isoquinolines have various effects and uses, and,are commonly used in Chinese medicine. Extremely,well-known and respected within his own field and,revered by many for his unparalleled research into,mind-altering substances, this new text is ideal,for botanists, chemists and fans alike.
The Simple Plant Isoquinolines
Author: Alexander Theodore Shulgin
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 672
Book Description
From the man who has done more research into,Ecstacy than any other chemist, author of the,best-selling Phenethylamines I Have Known and,Tyroptomines I Have Known, this is a comprehensive,reference work on isoquinolines found in plants.,Found in cactii and poppies among other plants,isoquinolines have various effects and uses, and,are commonly used in Chinese medicine. Extremely,well-known and respected within his own field and,revered by many for his unparalleled research into,mind-altering substances, this new text is ideal,for botanists, chemists and fans alike.
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 672
Book Description
From the man who has done more research into,Ecstacy than any other chemist, author of the,best-selling Phenethylamines I Have Known and,Tyroptomines I Have Known, this is a comprehensive,reference work on isoquinolines found in plants.,Found in cactii and poppies among other plants,isoquinolines have various effects and uses, and,are commonly used in Chinese medicine. Extremely,well-known and respected within his own field and,revered by many for his unparalleled research into,mind-altering substances, this new text is ideal,for botanists, chemists and fans alike.
The Chemistry and Biology of Isoquinoline Alkaloids
Author: J.D. Phillipson
Publisher: Springer Science & Business Media
ISBN: 3642701280
Category : Science
Languages : en
Pages : 315
Book Description
Isoquinolines form one of the largest groups of plant alkaloids and they in clude a number of valuable clinical agents such as codeine, morphine, eme tine and tubocurarine. Research into different aspects of isoquinolines con tinues in profusion, attracting the talents of botanists, chemists, bioche mists, analysts, pharmacists and pharmacologists. Many of these aspects are of an interdisciplinary nature, and in April 1984, The Phytochemical Society of Europe arranged a 3-day symposium on The Chemistry and Bi ology of Isoquinoline Alkaloids in order to provide a forum for scientists of differing disciplines who are united by a common interest in this one class of natural product. Each chapter in this volume is based on a lecture given at this symposium. Attempts have been made to make the aims and objectives, experimental findings and conclusions reached, intelligible to scientists of differing backgrounds. The introductory chapter, which is mainly based on a historical discus sion, stresses that plants containing isoquinolines have proved to be both a boon and a curse to mankind. The Opium Poppy, Papaver somniferum, produces the medicinally used alkaloids morphine, codeine, noscapine and papaverine whilst it also continues to provide drugs of abuse, particularly morphine and its readily prepared O,O-diacetyl derivative, heroin. Numer ous other alkaloids have been isolated from other members of the Papaver acea, and a knowledge of their presence and distribution within the various species has proved a useful adjunct to systematic botanical studies.
Publisher: Springer Science & Business Media
ISBN: 3642701280
Category : Science
Languages : en
Pages : 315
Book Description
Isoquinolines form one of the largest groups of plant alkaloids and they in clude a number of valuable clinical agents such as codeine, morphine, eme tine and tubocurarine. Research into different aspects of isoquinolines con tinues in profusion, attracting the talents of botanists, chemists, bioche mists, analysts, pharmacists and pharmacologists. Many of these aspects are of an interdisciplinary nature, and in April 1984, The Phytochemical Society of Europe arranged a 3-day symposium on The Chemistry and Bi ology of Isoquinoline Alkaloids in order to provide a forum for scientists of differing disciplines who are united by a common interest in this one class of natural product. Each chapter in this volume is based on a lecture given at this symposium. Attempts have been made to make the aims and objectives, experimental findings and conclusions reached, intelligible to scientists of differing backgrounds. The introductory chapter, which is mainly based on a historical discus sion, stresses that plants containing isoquinolines have proved to be both a boon and a curse to mankind. The Opium Poppy, Papaver somniferum, produces the medicinally used alkaloids morphine, codeine, noscapine and papaverine whilst it also continues to provide drugs of abuse, particularly morphine and its readily prepared O,O-diacetyl derivative, heroin. Numer ous other alkaloids have been isolated from other members of the Papaver acea, and a knowledge of their presence and distribution within the various species has proved a useful adjunct to systematic botanical studies.
The Isoquinoline Alkaloids
Author: K. W. Bentley
Publisher: Elsevier
ISBN: 1483152235
Category : Science
Languages : en
Pages : 273
Book Description
The Isoquinoline Alkaloids: A Course in Organic Chemistry is a description of the chemical structures of alkaloids. The book discusses the processes for degradation of isoquinoline alkaloids to recognizable compounds such as oxidation and exhaustive methylation. The associated processes in removing the nitrogen atom are also explained. The commonly used Hofmann process and the interpretation of its result are evaluated in the degradation of alkaloids. The cactus ""pellote"" used by Mexican Indians to induce hallucinatory experiences is examined. The active ingredient is identified as mescaline; its composition is analyzed to contain one primary amino and three methoxyl groups. The different syntheses made to duplicate mescaline are described. The structures of morphine, codeine, and thebain, which are all alkaloids of opium, are also analyzed. Another example of a principal alkaloid found in a plant is emetine found in the root of the ipecac. The pharmacological bases of emetine are isolated and noted as emetamine, cephaeline, psychotrine, and O-methylpsychotrine. The text also traces many other structural relationships within the subgroups of the isoquinoline alkaloids. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology will find this book informative.
Publisher: Elsevier
ISBN: 1483152235
Category : Science
Languages : en
Pages : 273
Book Description
The Isoquinoline Alkaloids: A Course in Organic Chemistry is a description of the chemical structures of alkaloids. The book discusses the processes for degradation of isoquinoline alkaloids to recognizable compounds such as oxidation and exhaustive methylation. The associated processes in removing the nitrogen atom are also explained. The commonly used Hofmann process and the interpretation of its result are evaluated in the degradation of alkaloids. The cactus ""pellote"" used by Mexican Indians to induce hallucinatory experiences is examined. The active ingredient is identified as mescaline; its composition is analyzed to contain one primary amino and three methoxyl groups. The different syntheses made to duplicate mescaline are described. The structures of morphine, codeine, and thebain, which are all alkaloids of opium, are also analyzed. Another example of a principal alkaloid found in a plant is emetine found in the root of the ipecac. The pharmacological bases of emetine are isolated and noted as emetamine, cephaeline, psychotrine, and O-methylpsychotrine. The text also traces many other structural relationships within the subgroups of the isoquinoline alkaloids. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology will find this book informative.
The Isoquinoline Alkaloids Chemistry and Pharmacology
Author: Maurice Shamma
Publisher: Elsevier
ISBN: 0323144500
Category : Science
Languages : en
Pages : 615
Book Description
The Isoquinoline Alkaloids: Chemistry and Pharmacology presents an overview of the chemistry, biogenesis, spectroscopy, and pharmacology of the isoquinoline alkaloids. This book examines the significant and interesting aspects of alkaloids. Organized into 32 chapters, this book starts with a discussion of the biogenesis of the isoquinolines and the various pharmacological effects of simple tetrahydroisoquinolines that have stimulant and convulsive properties. This text then explores the infrared absorptions, with emphasis on wavelength and frequency. Other chapters include topics on synthesis, degradation, reactions, absolute configuration, as well as on ultraviolet and nuclear magnetic resonance spectroscopy. This book further explores the various methods available for the preparation of simple tetrahydroisoquinolines, including the Bischler–Napieralski, Pictet–Spengler, and phenolic cyclization, as well as the Friedel–Crafts acylation. The last chapter deals with ancistrocladine, which is the first isoquinoline alkaloid found to possess a methyl group. Biochemists and biophysicists will find this book useful.
Publisher: Elsevier
ISBN: 0323144500
Category : Science
Languages : en
Pages : 615
Book Description
The Isoquinoline Alkaloids: Chemistry and Pharmacology presents an overview of the chemistry, biogenesis, spectroscopy, and pharmacology of the isoquinoline alkaloids. This book examines the significant and interesting aspects of alkaloids. Organized into 32 chapters, this book starts with a discussion of the biogenesis of the isoquinolines and the various pharmacological effects of simple tetrahydroisoquinolines that have stimulant and convulsive properties. This text then explores the infrared absorptions, with emphasis on wavelength and frequency. Other chapters include topics on synthesis, degradation, reactions, absolute configuration, as well as on ultraviolet and nuclear magnetic resonance spectroscopy. This book further explores the various methods available for the preparation of simple tetrahydroisoquinolines, including the Bischler–Napieralski, Pictet–Spengler, and phenolic cyclization, as well as the Friedel–Crafts acylation. The last chapter deals with ancistrocladine, which is the first isoquinoline alkaloid found to possess a methyl group. Biochemists and biophysicists will find this book useful.
Plant-derived Natural Products
Author: Anne E. Osbourn
Publisher: Springer Science & Business Media
ISBN: 0387854983
Category : Science
Languages : en
Pages : 588
Book Description
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Publisher: Springer Science & Business Media
ISBN: 0387854983
Category : Science
Languages : en
Pages : 588
Book Description
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.
Plant-derived Bioactives
Author: Mallappa Kumara Swamy
Publisher: Springer Nature
ISBN: 9811517614
Category : Science
Languages : en
Pages : 619
Book Description
Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.
Publisher: Springer Nature
ISBN: 9811517614
Category : Science
Languages : en
Pages : 619
Book Description
Plants produce a vast number of bioactive compounds with different chemical scaffolds, which modulate a diverse range of molecular targets and are used as drugs for treating numerous diseases. Most present-day medicines are derived either from plant compounds or their derivatives, and plant compounds continue to offer limitless reserves for the discovery of new medicines. While different classes of plant compounds, like phenolics, flavonoids, saponins and alkaloids, and their potential pharmacological applications are currently being explored, their curative mechanisms are yet to be understood in detail. This book is divided into 2 volumes and offers detailed information on plant-derived bioactive compounds, including recent research findings. Volume 1, Plant-derived Bioactives: Chemistry and Mode of Action, discusses the chemistry of highly valued plant bioactive compounds and their mode of actions at the molecular level. Volume 2, Plant-derived Bioactives: Production, Properties and Therapeutic Applications, explores the sources, biosynthesis, production, biological properties and therapeutic applications of plant bioactives. Given their scope, these books are valuable resources for members of the scientific community wishing to further explore various medicinal plants and the therapeutic applications of their bioactive compounds. They appeal to scholars, teachers and scientists involved in plant product research, and facilitate the development of innovative new drugs.
Biochemical Targets of Plant Bioactive Compounds
Author: Gideon Polya
Publisher: CRC Press
ISBN: 0203013719
Category : Science
Languages : en
Pages : 864
Book Description
When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.
Publisher: CRC Press
ISBN: 0203013719
Category : Science
Languages : en
Pages : 864
Book Description
When introduced to the human body, bioactive metabolites produced by plants for self defense bind to particular biochemical targets, most notably to proteins involved in signaling by hormones and neurotransmitters. This, essentially, is the basis for the effects of herbal medicine. While herbal medicine preparations may act by complex synergistic interactions, molecular explanations of herbal medicine efficacy and side effects ultimately require definition of the biochemical targets of individual plant bioactive constituents. Biochemical Targets of Plant Bioactive Compounds is a comprehensive and user-friendly reference guide to biochemical targets of plant defensive compounds. With 500 pages of tables, it presents a mine of succinctly summarized information relating to bioactive compound structures, plant sources, biochemical targets and physiological effects that can be readily accessed via chemical compound, plant genus, plant common name and subject indexes. With introductory chapters providing reviews of the structural diversity of plant defensive compounds and biochemistry, this book is an invaluable reference for biomedical professionals in the fields of alternative/complementary medicine, natural product chemistry, toxicology, pharmacology, and botany.
Natural Product Biosynthesis by Microorganisms and Plants, Part A
Author:
Publisher: Academic Press
ISBN: 0123946271
Category : Science
Languages : en
Pages : 487
Book Description
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The first of 3 volumes covering Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, Terpenoid biosynthesis in fungi, and plant Type III polyketide synthases. - Contains quality chapters authored by leaders in the field - The first of 3 volumes - Has chapters on such topics as kinetics of plant sesquiterpene synthases, terpenoid biosynthesis in fungi, and plant Type III polyketide synthases
Publisher: Academic Press
ISBN: 0123946271
Category : Science
Languages : en
Pages : 487
Book Description
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The first of 3 volumes covering Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, Terpenoid biosynthesis in fungi, and plant Type III polyketide synthases. - Contains quality chapters authored by leaders in the field - The first of 3 volumes - Has chapters on such topics as kinetics of plant sesquiterpene synthases, terpenoid biosynthesis in fungi, and plant Type III polyketide synthases
Biodiversity and Chemotaxonomy
Author: Kishan Gopal Ramawat
Publisher: Springer Nature
ISBN: 3030307468
Category : Science
Languages : en
Pages : 322
Book Description
Plant classifications are based on morphological characters and it is difficult, particularly in small plants and grasses, to identify these below generic level on the basis of these characters using a dissecting microscope. Plant species have intra- and inter-specific variation in secondary metabolites which can be utilized as marker compounds for identification and classification of plants. Secondary metabolites are produced as a result of primary metabolism and the production of these compounds not only involves several genes but also it is an energy dependent process. Hence these products cannot be considered as insignificant for the plant and the environment. Modern tools of molecular biology and secondary metabolites present in them can definitively decide about classification of plants. Absence of correct identification of plant is associated to many problems of resource utilization. Due to wide availability of these tools, interest has revived in systematics and correct classification of plants based on these parameters for their sustainable utilization and resource management. The purpose of this book is to assess the potential of phytochemical and molecular tools in the systematic and classification of plants. The topics covered include species concept, barcoding and phylogenetic analysis, chemotaxonomy use of polyketides, carotenes, cuticular wax, volatile oils, biodiversity of corals, metazoans, Ruta and Echinocereus. It provides comprehensive and broad subject-based reviews, useful for students, teachers, researchers, and all others interested in the field. The field has been kept wide and general to accommodate the wide-ranging topics. This book will be useful to agriculturists, chemists, botanists, industrialists, and those involved in planning of crop plants.
Publisher: Springer Nature
ISBN: 3030307468
Category : Science
Languages : en
Pages : 322
Book Description
Plant classifications are based on morphological characters and it is difficult, particularly in small plants and grasses, to identify these below generic level on the basis of these characters using a dissecting microscope. Plant species have intra- and inter-specific variation in secondary metabolites which can be utilized as marker compounds for identification and classification of plants. Secondary metabolites are produced as a result of primary metabolism and the production of these compounds not only involves several genes but also it is an energy dependent process. Hence these products cannot be considered as insignificant for the plant and the environment. Modern tools of molecular biology and secondary metabolites present in them can definitively decide about classification of plants. Absence of correct identification of plant is associated to many problems of resource utilization. Due to wide availability of these tools, interest has revived in systematics and correct classification of plants based on these parameters for their sustainable utilization and resource management. The purpose of this book is to assess the potential of phytochemical and molecular tools in the systematic and classification of plants. The topics covered include species concept, barcoding and phylogenetic analysis, chemotaxonomy use of polyketides, carotenes, cuticular wax, volatile oils, biodiversity of corals, metazoans, Ruta and Echinocereus. It provides comprehensive and broad subject-based reviews, useful for students, teachers, researchers, and all others interested in the field. The field has been kept wide and general to accommodate the wide-ranging topics. This book will be useful to agriculturists, chemists, botanists, industrialists, and those involved in planning of crop plants.
The Psychedelic Future of the Mind
Author: Thomas B. Roberts
Publisher: Simon and Schuster
ISBN: 1594775028
Category : Body, Mind & Spirit
Languages : en
Pages : 251
Book Description
Explores scientific and medical research on the emerging uses of psychedelics to enrich mind, morals, spirituality, and creativity • Outlines a future that embraces psychedelics as tools for cognitive development, personal growth, business, and an experience-based religious reformation • Presents research on the use of psychedelics to enhance problem-solving, increase motivation, boost the immune system, and deepen ethical values • Includes chapters by Roger N. Walsh, M.D., Ph.D., and Charles Grob, M.D., on their psychedelic research on religious experience and alleviating the fear of death As psychedelic psychotherapy gains recognition through research at universities and medical establishments such as the Johns Hopkins Medical Institute and Bellevue Hospital, the other beneficial uses of psychedelics are beginning to be recognized and researched as well--from enhancing problem-solving and increasing motivation to boosting the immune system and deepening moral and ethical values. Exploring the bright future of psychedelics, Thomas B. Roberts, Ph.D., reveals how new uses for entheogens will enrich individuals as well as society as a whole. With contributions from Charles Grob, M.D., and Roger N. Walsh, M.D., Ph.D., the book explains how psychedelics can raise individual and business attitudes away from self-centeredness, improve daily life with strengthened feelings of meaningfulness and spirituality, and help us understand and redesign the human mind, leading to the possibility of a neurosingularity--a time when future brains surpass our current ones. Roberts envisions a future where you will seek psychedelic therapy not only for psychological reasons but also for personal growth, creative problem solving, improved brain function, and heightened spiritual awareness. Our psychedelic future is on the horizon--a future that harnesses the full potential of mind and spirit--and Thomas Roberts outlines a path to reach it.
Publisher: Simon and Schuster
ISBN: 1594775028
Category : Body, Mind & Spirit
Languages : en
Pages : 251
Book Description
Explores scientific and medical research on the emerging uses of psychedelics to enrich mind, morals, spirituality, and creativity • Outlines a future that embraces psychedelics as tools for cognitive development, personal growth, business, and an experience-based religious reformation • Presents research on the use of psychedelics to enhance problem-solving, increase motivation, boost the immune system, and deepen ethical values • Includes chapters by Roger N. Walsh, M.D., Ph.D., and Charles Grob, M.D., on their psychedelic research on religious experience and alleviating the fear of death As psychedelic psychotherapy gains recognition through research at universities and medical establishments such as the Johns Hopkins Medical Institute and Bellevue Hospital, the other beneficial uses of psychedelics are beginning to be recognized and researched as well--from enhancing problem-solving and increasing motivation to boosting the immune system and deepening moral and ethical values. Exploring the bright future of psychedelics, Thomas B. Roberts, Ph.D., reveals how new uses for entheogens will enrich individuals as well as society as a whole. With contributions from Charles Grob, M.D., and Roger N. Walsh, M.D., Ph.D., the book explains how psychedelics can raise individual and business attitudes away from self-centeredness, improve daily life with strengthened feelings of meaningfulness and spirituality, and help us understand and redesign the human mind, leading to the possibility of a neurosingularity--a time when future brains surpass our current ones. Roberts envisions a future where you will seek psychedelic therapy not only for psychological reasons but also for personal growth, creative problem solving, improved brain function, and heightened spiritual awareness. Our psychedelic future is on the horizon--a future that harnesses the full potential of mind and spirit--and Thomas Roberts outlines a path to reach it.