The Role of Retinoblastoma Protein and Insulin Like Growth Factor Signaling in Antiestrogen Resistance

The Role of Retinoblastoma Protein and Insulin Like Growth Factor Signaling in Antiestrogen Resistance PDF Author: Hemant Varma
Publisher:
ISBN:
Category : Breast
Languages : en
Pages : 328

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The Role of Retinoblastoma Protein and Insulin Like Growth Factor Signaling in Antiestrogen Resistance

The Role of Retinoblastoma Protein and Insulin Like Growth Factor Signaling in Antiestrogen Resistance PDF Author: Hemant Varma
Publisher:
ISBN:
Category : Breast
Languages : en
Pages : 328

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Journal of the National Cancer Institute

Journal of the National Cancer Institute PDF Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 372

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Insulin-like Growth Factor Receptor Signalling

Insulin-like Growth Factor Receptor Signalling PDF Author: Derek Leroith
Publisher: Springer Science & Business Media
ISBN: 9780306478468
Category : Medical
Languages : en
Pages : 524

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Book Description
Insulin-like growth factors are ubiquitously expressed and are crucial for growth and function of almost all cells. Together with their binding proteins and receptors, they form a widely studied biological system involving many proteins and characterized by complex interactions. In addition to its significance in growth and development, the insulin-like growth factor system also has important roles in a wide variety of pathological states. This has led to interest in the therapeutic potential of insulin-like growth factors and their binding proteins as candidate drug targets. This comprehensive book contains current information on both basic science and clinical aspects of IGFs and their regulatory proteins, with emphasis on their relevance to cancer.

DeVita, Hellman, and Rosenberg's Cancer

DeVita, Hellman, and Rosenberg's Cancer PDF Author: Vincent T. DeVita
Publisher: Lippincott Williams & Wilkins
ISBN: 149639464X
Category : Medical
Languages : en
Pages : 6979

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Book Description
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more.

Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 854

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Epithelial-Mesenchymal Plasticity in Cancer Metastasis

Epithelial-Mesenchymal Plasticity in Cancer Metastasis PDF Author: Mohit Kumar Jolly
Publisher: MDPI
ISBN: 3039367242
Category : Medical
Languages : en
Pages : 512

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Book Description
Recent studies have highlighted that epithelial-mesenchymal transition (EMT) is not only about cell migration and invasion, but it can also govern many other important elements such as immunosuppression, metabolic reprogramming, senescence-associated secretory phenotype (SASP), stem cell properties, therapy resistance, and tumor microenvironment interactions. With the on-going debate about the requirement of EMT for cancer metastasis, an emerging focus on intermediate states of EMT and its reverse process mesenchymal-epithelial transition (MET) offer new ideas for metastatic requirements and the dynamics of EMT/MET during the entire metastatic cascade. Therefore, we would like to initiate discussions on viewing EMT and its downstream signaling networks as a fulcrum of cellular plasticity, and a facilitator of the adaptive responses of cancer cells to distant organ microenvironments and various therapeutic assaults. We hereby invite scientists who have prominently contributed to this field, and whose valuable insights have led to the appreciation of epithelial-mesenchymal plasticity as a more comprehensive mediator of the adaptive response of cancer cells, with huge implications in metastasis, drug resistance, tumor relapse, and patient survival.

Weight Control and Physical Activity

Weight Control and Physical Activity PDF Author: Harri Vainio
Publisher: IARC
ISBN: 9789283230069
Category : Health & Fitness
Languages : en
Pages : 346

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Book Description
Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.

Insulin-like Growth Factors

Insulin-like Growth Factors PDF Author: Derek LeRoith
Publisher: CRC Press
ISBN: 9780849357121
Category : Medical
Languages : en
Pages : 328

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Book Description
During the past decade, the continued interest in insulin-related growth factors has been documented by a plethora of research programs and publications focused on these growth factors. Both molecular and cellular biological techniques have improved and enabled investigators to study the properties of the growth factors in depth. This volume covers the molecular (genetic) aspects of the growth factors, their binding proteins and receptors, as well as those factors affecting their gene transcription and translation. In addition, aspects of the cellular action of these growth factors through their receptors and how this impacts normal cellular function are discussed. The book will provide valuable information for researchers in physiology, biology, endocrinology, and metabolism.

Breast Cancer Biology

Breast Cancer Biology PDF Author: Dil Afroze
Publisher: BoD – Books on Demand
ISBN: 1789239613
Category : Medical
Languages : en
Pages : 127

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Book Description
This book offers a comprehensive overview of recent developments in the field of breast cancer biology. It is a complete and descriptive reference on motioning pathways and new treatment options for the future transnational scientists and clinicians working on cancer research and treatment. We greatly appreciate the work of all the contributors to this book. They have brought with them tremendous diversity of perspectives and fields, which is truly reflective of the complexity of the topic, and they have come together in this project to serve as the node of multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies, and who have inspired us to gather information to significantly progress knowledge in the field in recent years.

Retinoblastoma

Retinoblastoma PDF Author: Govindasamy Kumaramanickavel
Publisher: BoD – Books on Demand
ISBN: 9535104357
Category : Medical
Languages : en
Pages : 184

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Book Description
Retinoblastoma is the first tumor suppressor gene discovered ever. The discovery opened a new avenue in the field of oncology leading to the identification of 35 tumor suppressor genes, till date in our genome. This book is an excellent compilation of both clinical and basic science information that meets the needs of a young clinician and a researcher at the same time. It also has abundant information on recent advances and cutting-edge knowledge in intracellular molecular cross-talking of retinoblastoma protein with various cellular viral-like proteins.