The Regulation of Stat5A Expression and Its Function in the Developing Mouse Mammary Gland PDF Download
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Author: Sarah Jane Santos
Publisher:
ISBN:
Category : Cellular signal transduction
Languages : en
Pages : 282
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Book Description
Author: Sarah Jane Santos
Publisher:
ISBN:
Category : Cellular signal transduction
Languages : en
Pages : 282
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Book Description
Author: Bert W. O'Malley
Publisher:
ISBN:
Category : Cyclic nucleotides
Languages : en
Pages : 488
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Book Description
Hormone assays; Hormone receptors; Evaluation of biological effects of hormones; Purification and synthesis of hormones.
Author: John A. Mol
Publisher: Springer
ISBN: 9781475786422
Category : Science
Languages : en
Pages : 314
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Book Description
Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Author: Brigid Hogan
Publisher: Cold Spring Harbor Laboratory Press
ISBN:
Category : Nature
Languages : en
Pages : 352
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Book Description
Of mouse development -- Setting up a colony for the production of transgenic mice -- Recovery, culture, and transfer of embryos -- Introduction of new genetic information into the developing mouse embryo -- Iolation of pluripotential stem cell lines -- Techhniques for visualizing genes and gene products -- In vitro culture of eggs, embryos, and teratocarcinoma cels -- Chemicals, supplies, and solutions.
Author: Vincent Goffin
Publisher: Springer Science & Business Media
ISBN: 9780792376606
Category : Medical
Languages : en
Pages : 340
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Book Description
Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.
Author: Jen-Chywan Wang
Publisher: Springer
ISBN: 1493928953
Category : Science
Languages : en
Pages : 387
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Book Description
This timely volume provides a comprehensive overview of glucocorticoids and their role in regulating many aspects of physiology and their use in the treatment of disease. The book is broken into four sections that begin by giving a general introduction to glucocorticoids and a brief history of the field. The second section will discuss the effects of glucocorticoids on metabolism, while the third section will cover the effects of glucocorticoids on key tissues. The final section will discuss general topics, such as animal models in glucocorticoid research and clinical implications of glucocorticoid research. Featuring chapters from leaders in the field, this volume will be of interest to both researchers and clinicians.
Author: Zsuzsanna Bosze
Publisher: Springer Science & Business Media
ISBN: 0387740872
Category : Technology & Engineering
Languages : en
Pages : 492
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Book Description
Dairy foods have huge potential concerning functional foods. Therefore, there is a tremendous amount of interest in value-added milk products and the identification of components in food which have health benefits. This book provides an overview of these derived components and their diverse activities including: the stimulation of beneficial microflora, alerting the immune system to the presence of potential pathogens and allergens, binding and eliminating toxins, etc.
Author: James J. Lee
Publisher: Academic Press
ISBN: 012394385X
Category : Health & Fitness
Languages : en
Pages : 679
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Book Description
Eosinophils in Health and Disease provides immunology researchers and students with a comprehensive overview of current thought and cutting-edge eosinophil research, providing chapters on basic science, disease-specific issues, therapeutics, models for study and areas of emerging importance.
Author: Margot M. Ip
Publisher: Springer Science & Business Media
ISBN: 9780306463976
Category : Medical
Languages : en
Pages : 366
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Book Description
This book is a bench manual that provides in one volume all theimportant and unique technologies necessary to studies of mammarygland biology and breast cancer. The chapters are written by expertsin each area with an emphasis on nitty-gritty details that are keypoints for the successful use of a method. Sections include "in""vivo" model systems, special techniques for "in vivo"studies, "in vitro" model systems, and molecular analysis and genetransfer techniques.
Author: Angus W. Thomson
Publisher: Gulf Professional Publishing
ISBN: 9780126896633
Category : Chemokines
Languages : en
Pages : 878
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Book Description
The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Expanded to two volumes, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems.
