Author: Louise E. Mitchell
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
In order for cells to proliferate, a certain size has to be reached, which depends primarily on the rate of translation. RNA polymerase (pol) III plays a key role in protein synthesis by catalysing the production of small, untranslated RNA molecules such as transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Indeed, recent evidence suggests that tRNAiMet production is limiting for translation and proliferation in some cell types. Therefore, the rate of pol III transcription plays a fundamental role in cellular growth and proliferation. Regulation of pol III output is mediated via a number of different mechanisms that can alter the activities of the transcription factors which are responsible for directing pol III transcription. Work presented in this thesis aimed at investigating the mechanisms behind the regulation of pol III transcription by the protein kinase CK2.
The Regulation of RNA Polymerase III Transcription by Protein Kinase CK2
Author: Louise E. Mitchell
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
In order for cells to proliferate, a certain size has to be reached, which depends primarily on the rate of translation. RNA polymerase (pol) III plays a key role in protein synthesis by catalysing the production of small, untranslated RNA molecules such as transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Indeed, recent evidence suggests that tRNAiMet production is limiting for translation and proliferation in some cell types. Therefore, the rate of pol III transcription plays a fundamental role in cellular growth and proliferation. Regulation of pol III output is mediated via a number of different mechanisms that can alter the activities of the transcription factors which are responsible for directing pol III transcription. Work presented in this thesis aimed at investigating the mechanisms behind the regulation of pol III transcription by the protein kinase CK2.
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
In order for cells to proliferate, a certain size has to be reached, which depends primarily on the rate of translation. RNA polymerase (pol) III plays a key role in protein synthesis by catalysing the production of small, untranslated RNA molecules such as transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Indeed, recent evidence suggests that tRNAiMet production is limiting for translation and proliferation in some cell types. Therefore, the rate of pol III transcription plays a fundamental role in cellular growth and proliferation. Regulation of pol III output is mediated via a number of different mechanisms that can alter the activities of the transcription factors which are responsible for directing pol III transcription. Work presented in this thesis aimed at investigating the mechanisms behind the regulation of pol III transcription by the protein kinase CK2.
Regulation of RNA Polymerase III Transcription by TATA Binding Protein-associated CK2
Author: Ataollah Ghavidel
Publisher:
ISBN:
Category : Fertility, Human
Languages : en
Pages : 272
Book Description
Publisher:
ISBN:
Category : Fertility, Human
Languages : en
Pages : 272
Book Description
Regulation of Human Small Nuclear RNA Gene Transcription by the Oncogenic Protein Kinase CK2
Author: Liping Gu
Publisher:
ISBN:
Category : Cellular signal transduction
Languages : en
Pages : 318
Book Description
Publisher:
ISBN:
Category : Cellular signal transduction
Languages : en
Pages : 318
Book Description
RNA Polymerase III Transcription
Author: Robert J. White
Publisher: Springer Science & Business Media
ISBN: 3662035189
Category : Science
Languages : en
Pages : 274
Book Description
This monograph reviews and summarizes the substantial body of work that has been published on the transcription by polymerase III over the past 5 years. Progress in this field has been very rapid since 1993, and this new edition incorporates all the recent developments and offers the reader a highly detailed analysis of the current state of research on this largest and most complex of the eukaryotic RNA polymerases.
Publisher: Springer Science & Business Media
ISBN: 3662035189
Category : Science
Languages : en
Pages : 274
Book Description
This monograph reviews and summarizes the substantial body of work that has been published on the transcription by polymerase III over the past 5 years. Progress in this field has been very rapid since 1993, and this new edition incorporates all the recent developments and offers the reader a highly detailed analysis of the current state of research on this largest and most complex of the eukaryotic RNA polymerases.
Protein Kinases and the Regulation of Transcription by RNA Polymerase III
Author: Romi Ghose
Publisher:
ISBN:
Category :
Languages : en
Pages : 384
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 384
Book Description
Regulation of RNA Polymerase III Transcription in Xenopus
Author: Michael Robert Sturges
Publisher:
ISBN:
Category : Genetic transcription
Languages : en
Pages : 264
Book Description
Publisher:
ISBN:
Category : Genetic transcription
Languages : en
Pages : 264
Book Description
Regulation of Human RNA Polymerase III Transcription by RB Family Members
Author: Xianzhou Song
Publisher:
ISBN:
Category : Genetic transcription
Languages : en
Pages : 200
Book Description
Publisher:
ISBN:
Category : Genetic transcription
Languages : en
Pages : 200
Book Description
Regulation of Polymerase III Transcription
Author: Noelle Dominique L'Étoile
Publisher:
ISBN:
Category :
Languages : en
Pages : 246
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 246
Book Description
The Regulation of RNA Polymerase I and RNA Polymerase III Transcription by the Pocket Proteins
Author: Josephine E. Sutcliffe
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
A Molecular and Cellular View of Protein Kinase CK2
Author: Khalil Ahmed
Publisher: Springer Science & Business Media
ISBN: 1441986243
Category : Science
Languages : en
Pages : 234
Book Description
It is now generally recognized that protein kinase signaling is involved in virtually every aspect of cell function, including growth and proliferation. The field of protein phosphorylation, including the enzymes involved in this post-translational modification, continues to advance at a fascinating pace. Since the first international meeting on this topic, held in Heidelberg in 1994, several new avenues of CK2 research have emerged despite persistent deficiencies in our understanding of the regulation of its activity. Among the significant new directions are studies related to the structure of the enzyme, especially its crystal structure, as well as an interesting aspect of CK2 function that involves its subunits as binding partners of several other proteins. In addition, new data have been gathered on the role of CK2 in transcription as well as in certain other cellular functions. To address these various aspects of the progress of CK2, a number of key scientists from different parts of the world came together at the second international meeting on `A Molecular and Cellular View of Protein Kinase CK2', held at Villard de Lans near Grenoble on September 24-26, 1997. The meeting was attended by nearly 50 participants and included 28 presentations, which provide a view of the latest progress on protein kinase CK2.
Publisher: Springer Science & Business Media
ISBN: 1441986243
Category : Science
Languages : en
Pages : 234
Book Description
It is now generally recognized that protein kinase signaling is involved in virtually every aspect of cell function, including growth and proliferation. The field of protein phosphorylation, including the enzymes involved in this post-translational modification, continues to advance at a fascinating pace. Since the first international meeting on this topic, held in Heidelberg in 1994, several new avenues of CK2 research have emerged despite persistent deficiencies in our understanding of the regulation of its activity. Among the significant new directions are studies related to the structure of the enzyme, especially its crystal structure, as well as an interesting aspect of CK2 function that involves its subunits as binding partners of several other proteins. In addition, new data have been gathered on the role of CK2 in transcription as well as in certain other cellular functions. To address these various aspects of the progress of CK2, a number of key scientists from different parts of the world came together at the second international meeting on `A Molecular and Cellular View of Protein Kinase CK2', held at Villard de Lans near Grenoble on September 24-26, 1997. The meeting was attended by nearly 50 participants and included 28 presentations, which provide a view of the latest progress on protein kinase CK2.