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Author: Thom Rooke
Publisher: MSU Press
ISBN: 1609173260
Category : Medical
Languages : en
Pages : 376
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Book Description
In 1948, when “Mrs. G.,” hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound—cortisone—her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought “magic bullet” came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone’s development, and looks at drugs that owe their heritage to the so-called “King of Steroids.”
Author: Thom Rooke
Publisher: MSU Press
ISBN: 1609173260
Category : Medical
Languages : en
Pages : 376
Get Book Here
Book Description
In 1948, when “Mrs. G.,” hospitalized with debilitating rheumatoid arthritis, became the first person to receive a mysterious new compound—cortisone—her physicians were awestruck by her transformation from enervated to energized. After eighteen years of biochemical research, the most intensively hunted biological agent of all time had finally been isolated, identified, synthesized, and put to the test. And it worked. But the discovery of a long-sought “magic bullet” came at an unanticipated cost in the form of strange side effects. This fascinating history recounts the discovery of cortisone and pulls the curtain back on the peculiar cast of characters responsible for its advent, including two enigmatic scientists, Edward Kendall and Philip Hench, who went on to receive the Nobel Prize. The book also explores the key role the Mayo Clinic played in fostering cortisone’s development, and looks at drugs that owe their heritage to the so-called “King of Steroids.”
Author: Eric Goodman
Publisher: Rodale Books
ISBN: 1609617711
Category : Health & Fitness
Languages : en
Pages : 290
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Book Description
A sense of fatigue dogs the fitness world. Many of the new programs that are tagged as groundbreaking are actually recycled ideas. Foundation offers something completely different for novices and athletes alike: a simple program with powerful and proven results that will remedy bad posture, alleviate back pain, and help readers break through fitness challenges and plateaus. Dr. Eric Goodman, a brilliant and dynamic young chiropractor, teams up with Peter Park, one of the top trainers in the United States, to radically redefine the core--shifting the focus from the front of the body to the back. Their groundbreaking approach works to strengthen the lower back and the full posterior chain and correct poor movement patterns by addressing mechanical imbalances and weaknesses. Foundation training involves simple movement patterns and is equipment free, creating maximum power, flexibility, and endurance. Word-of-mouth enthusiasm has inspired both Hollywood luminaries and world-class athletes to make Foundation training the core of their fitness programs. Eric and Peter's client list has grown exponentially to include Lance Armstrong, NBA star Derek Fisher, world-champion surfer Kelly Slater, and actor Matthew McConaughey.
Author: Barry Werth
Publisher: Simon and Schuster
ISBN: 143912681X
Category : Business & Economics
Languages : en
Pages : 480
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Book Description
Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.
Author: Beth Macy
Publisher: Little, Brown
ISBN: 0316337560
Category : History
Languages : en
Pages : 496
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Book Description
The true story of two African-American brothers who were kidnapped and displayed as circus freaks, and whose mother endured a 28-year struggle to get them back. The year was 1899 and the place a sweltering tobacco farm in the Jim Crow South town of Truevine, Virginia. George and Willie Muse were two little boys born to a sharecropper family. One day a white man offered them a piece of candy, setting off events that would take them around the world and change their lives forever. Captured into the circus, the Muse brothers performed for royalty at Buckingham Palace and headlined over a dozen sold-out shows at New York's Madison Square Garden. They were global superstars in a pre-broadcast era. But the very root of their success was in the color of their skin and in the outrageous caricatures they were forced to assume: supposed cannibals, sheep-headed freaks, even "Ambassadors from Mars." Back home, their mother never accepted that they were "gone" and spent 28 years trying to get them back. Through hundreds of interviews and decades of research, Beth Macy expertly explores a central and difficult question: Where were the brothers better off? On the world stage as stars or in poverty at home? Truevine is a compelling narrative rich in historical detail and rife with implications to race relations today.
Author: Gabriela Soto Laveaga
Publisher: Duke University Press
ISBN: 0822391961
Category : History
Languages : en
Pages : 347
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Book Description
In the 1940s chemists discovered that barbasco, a wild yam indigenous to Mexico, could be used to mass-produce synthetic steroid hormones. Barbasco spurred the development of new drugs, including cortisone and the first viable oral contraceptives, and positioned Mexico as a major player in the global pharmaceutical industry. Yet few people today are aware of Mexico’s role in achieving these advances in modern medicine. In Jungle Laboratories, Gabriela Soto Laveaga reconstructs the story of how rural yam pickers, international pharmaceutical companies, and the Mexican state collaborated and collided over the barbasco. By so doing, she sheds important light on a crucial period in Mexican history and challenges us to reconsider who can produce science. Soto Laveaga traces the political, economic, and scientific development of the global barbasco industry from its emergence in the 1940s, through its appropriation by a populist Mexican state in 1970, to its obsolescence in the mid-1990s. She focuses primarily on the rural southern region of Tuxtepec, Oaxaca, where the yam grew most freely and where scientists relied on local, indigenous knowledge to cultivate and harvest the plant. Rural Mexicans, at first unaware of the pharmaceutical and financial value of barbasco, later acquired and deployed scientific knowledge to negotiate with pharmaceutical companies, lobby the Mexican government, and ultimately transform how urban Mexicans perceived them. By illuminating how the yam made its way from the jungles of Mexico, to domestic and foreign scientific laboratories where it was transformed into pills, to the medicine cabinets of millions of women across the globe, Jungle Laboratories urges us to recognize the ways that Mexican peasants attained social and political legitimacy in the twentieth century, and positions Latin America as a major producer of scientific knowledge.
Author: Barry Werth
Publisher: Simon and Schuster
ISBN: 1451655665
Category : Business & Economics
Languages : en
Pages : 448
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Book Description
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Journalist Barry Werth described the company's tumultuous early days during the AIDS crisis in The Billion-Dollar Molecule, a celebrated classic of science and business journalism. Now he returns to tell the story of Vertex's bold endurance and eventual success. The pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power. Werth captures the full scope of Vertex's 25-year drive to deliver breakthrough medicines.--From publisher description.
Author: James Le Fanu
Publisher: Basic Books
ISBN: 9780786709670
Category : Medical
Languages : en
Pages : 448
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Book Description
In the years following World War II, medicine won major battles against smallpox, diphtheria, and polio. In the same period it also produced treatments to control the progress of Parkinson's, rheumatoid arthritis, and schizophrenia. It made realities of open-heart surgery, organ transplants, test-tube babies. Unquestionably, the medical accomplishments of the postwar years stand at the forefront of human endeavor, yet progress in recent decades has slowed nearly to a halt. In this winner of the Los Angeles Times Book Prize, medical doctor and columnist James Le Fanu both surveys the glories of medicine in the postwar years and analyzes the factors that for the past twenty-five years have increasingly widened the gulf between achievement and advancement: the social theories of medicine, ethical issues, and political debates over health care that have hobbled the development of vaccines and discovery of new "miracle" cures. While fully demonstrating the extraordinary progress effected by medical research in the latter half of the twentieth century, Le Fanu also identifies the perils that confront medicine in the twenty-first. 16 pages of black-and-white photographs add to what the Los Angeles Times cited as "a sobering, contrarian challenge" to the "nostrum of medicine as a never-ending font of ‘miracle cures'." "[From] a respected science writer ... important information that ... has been overlooked or ignored by many physicians." —New Republic "Provocative and engrossing and informative." —Houston Chronicle "Marvelously written, meticulously researched ... one of the most thought-provoking and important works to appear in recent years." —Choice
Author: Joe Vitale
Publisher: John Wiley & Sons
ISBN: 1118837479
Category : Business & Economics
Languages : en
Pages : 245
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Book Description
New stories and new processes that outline the fourth stage of awakening of ho'oponopono Author Joe Vitale's previous book, Zero Limits, presented a unique self-help breakthrough focused on helping overworked, overstressed individuals overcome obstacles and achieve their goals. It was the first book to explain how a secret Hawaiian method called ho'oponopono can help people experience health, wealth, happiness, and more. It empowered thousands of readers to take control of everything in their lives in order to achieve all they’ve ever dreamed of. At Zero starts where Zero Limits left off. It offers new stories, explains new process, and reveals the fourth stage of awakening. Explains the process called "cleaning," to delete programs and beliefs that you aren't aware of Shows how repeating the phrases I love you, I'm sorry, Please forgive me, Thank you can help you reach Divinity Life will always present you with challenges. The practice of ho'oponopono, as revealed by author Joe Vitale, guides you through the journey of life with the tools you need to rid yourself of hindrances and open yourself up to infinite possibilities.
Author: Vincent Kiernan
Publisher: Cornell University Press
ISBN: 1501766007
Category : History
Languages : en
Pages : 312
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Book Description
In Atomic Bill, Vincent Kiernan examines the fraught career of New York Times science journalist, William L. Laurence and shows his professional and personal lives to be a cautionary tale of dangerous proximity to power. Laurence was fascinated with atomic science and its militarization. When the Manhattan Project drew near to perfecting the atomic bomb, he was recruited to write much of the government's press materials that were distributed on the day that Hiroshima was obliterated. That instantly crowned Laurence as one of the leading journalistic experts on the atomic bomb. As the Cold War dawned, some assessed Laurence as a propagandist defending the militarization of atomic energy. For others, he was a skilled science communicator who provided the public with a deep understanding of the atomic bomb. Laurence leveraged his perch at the Times to engage in paid speechmaking, book writing, filmmaking, and radio broadcasting. His work for the Times declined in quality even as his relationships with people in power grew closer and more lucrative. Atomic Bill reveals extraordinary ethical lapses by Laurence such as a cheating scandal at Harvard University and plagiarizing from press releases about atomic bomb tests in the Pacific. In 1963 a conflict of interest related to the 1964 World's Fair in New York City led to his forced retirement from the Times. Kiernan shows Laurence to have set the trend, common among today's journalists of science and technology, to prioritize gee-whiz coverage of discoveries. That approach, in which Laurence served the interests of governmental official and scientists, recommends a full revision of our understanding of the dawn of the atomic era.
Author: Mark Morris
Publisher: Penguin
ISBN: 0735223084
Category : Biography & Autobiography
Languages : en
Pages : 385
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Book Description
From the most brilliant and audacious choreographer of our time, the exuberant tale of a young dancer’s rise to the pinnacle of the performing arts world, and the triumphs and perils of creating work on his own terms—and staying true to himself Before Mark Morris became “the most successful and influential choreographer alive” (The New York Times), he was a six year-old in Seattle cramming his feet into Tupperware glasses so that he could practice walking on pointe. Often the only boy in the dance studio, he was called a sissy, a term he wore like a badge of honor. He was unlike anyone else, deeply gifted and spirited. Moving to New York at nineteen, he arrived to one of the great booms of dance in America. Audiences in 1976 had the luxury of Merce Cunningham’s finest experiments with time and space, of Twyla Tharp’s virtuosity, and Lucinda Childs's genius. Morris was flat broke but found a group of likeminded artists that danced together, travelled together, slept together. No one wanted to break the spell or miss a thing, because “if you missed anything, you missed everything.” This collective, led by Morris’s fiercely original vision, became the famed Mark Morris Dance Group. Suddenly, Morris was making a fast ascent. Celebrated by The New Yorker’s critic as one of the great young talents, an androgynous beauty in the vein of Michelangelo’s David, he and his company had arrived. Collaborations with the likes of Mikhail Baryshnikov, Yo-Yo Ma, Lou Harrison, and Howard Hodgkin followed. And so did controversy: from the circus of his tenure at La Monnaie in Belgium to his work on the biggest flop in Broadway history. But through the Reagan-Bush era, the worst of the AIDS epidemic, through rehearsal squabbles and backstage intrigues, Morris emerged as one of the great visionaries of modern dance, a force of nature with a dedication to beauty and a love of the body, an artist as joyful as he is provocative. Out Loud is the bighearted and outspoken story of a man as formidable on the page as he is on the boards. With unusual candor and disarming wit, Morris’s memoir captures the life of a performer who broke the mold, a brilliant maverick who found his home in the collective and liberating world of music and dance.
