G-Quadruplex Nucleic Acids PDF Download
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Author: Danzhou Yang
Publisher: Humana
ISBN: 9781493996650
Category : Medical
Languages : en
Pages : 437
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Book Description
This volume covers the structures, properties, and functions of G-quadruplexes in a wide range of biological disciplines, including therapeutic intervention and biomaterial application. The chapters in this book explore a wide range of vital and new experimental techniques used in the study of G-quadruplexes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, G-Quadruplex DNA: Methods and Protocols is a valuable resource for both novice and experienced researchers who work in biophysics, structural biology, computational biology, biochemistry, and molecular and cell biology, and who want to learn more about the potential roles and effects of G-quadruplex in these fields.
Author: Danzhou Yang
Publisher: Humana
ISBN: 9781493996650
Category : Medical
Languages : en
Pages : 437
Get Book Here
Book Description
This volume covers the structures, properties, and functions of G-quadruplexes in a wide range of biological disciplines, including therapeutic intervention and biomaterial application. The chapters in this book explore a wide range of vital and new experimental techniques used in the study of G-quadruplexes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and cutting-edge, G-Quadruplex DNA: Methods and Protocols is a valuable resource for both novice and experienced researchers who work in biophysics, structural biology, computational biology, biochemistry, and molecular and cell biology, and who want to learn more about the potential roles and effects of G-quadruplex in these fields.
Author:
Publisher: Academic Press
ISBN: 0128210184
Category : Science
Languages : en
Pages : 566
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Book Description
The realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Annual Reports in Medicinal Chemistry series
Author: Stephen Neidle
Publisher: Royal Society of Chemistry
ISBN: 1847555292
Category : Science
Languages : en
Pages : 317
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Book Description
Guanine rich DNA has been known for decades to form unusual structures, although their biological relevance was little understood. Recent advances have demonstrated that quadruplex structures can play a role in gene expression and provide opportunities for a new class of anticancer therapeutics. A number of quadruplex-specific proteins have also been discovered. Quadruplex Nucleic Acids discusses all aspects of the fundamentals of quadruplex structures, including their structure in solution and the crystalline state, the kinetics of quadruplex folding, and the role of cations in structure and stability. The biology of quadruplexes and G-rich genomic regions and G-quartets in supramolecular chemistry and nanoscience are also considered. Surveying the current state of knowledge, and with contributions from leading experts, this is the first comprehensive review of this rapidly growing area. Quadruplex Nucleic Acids is ideal for researchers interested in areas related to chemistry, chemical biology, medicinal chemistry, molecular pharmacology, and structural and molecular biology.
Author: Association of American Railroads. Communications Section
Publisher:
ISBN:
Category :
Languages : en
Pages : 614
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Book Description
Author:
Publisher:
ISBN:
Category : Ford automobile
Languages : en
Pages : 724
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Book Description
Author: Wolfgang Fritzsche
Publisher: Royal Society of Chemistry
ISBN: 1849734607
Category : Science
Languages : en
Pages : 357
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Book Description
This book explores in detail guanosine and its derivative with the goal of increasing knowledge of the basic principles of guanosine-assembly, synthesis of new optimised materials and exploration of their electronic and optical properties.
Author: Eugen Stulz
Publisher: John Wiley & Sons
ISBN: 111869693X
Category : Technology & Engineering
Languages : en
Pages : 538
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Book Description
This book covers the emerging topic of DNA nanotechnology and DNA supramolecular chemistry in its broader sense. By taking DNA out of its biological role, this biomolecule has become a very versatile building block in materials chemistry, supramolecular chemistry and bio-nanotechnology. Many novel structures have been realized in the past decade, which are now being used to create molecular machines, drug delivery systems, diagnosis platforms or potential electronic devices. The book combines many aspects of DNA nanotechnology, including formation of functional structures based on covalent and non-covalent systems, DNA origami, DNA based switches, DNA machines, and alternative structures and templates. This broad coverage is very appealing since it combines both the synthesis of modified DNA as well as designer concepts to successfully plan and make DNA nanostructures. Contributing authors have provided first a general introduction for the non-specialist reader, followed by a more in-depth analysis and presentation of their topic. In this way the book is attractive and useful for both the non-specialist who would like to have an overview of the topic, as well as the specialist reader who requires more information and inspiration to foster their own research.
Author:
Publisher: ScholarlyEditions
ISBN: 1464963894
Category : Science
Languages : en
Pages : 2344
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Book Description
Issues in Biochemistry and Geochemistry / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biochemistry and Geochemistry. The editors have built Issues in Biochemistry and Geochemistry: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biochemistry and Geochemistry in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biochemistry and Geochemistry / 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Western Union Telegraph Company
Publisher:
ISBN:
Category :
Languages : en
Pages : 54
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Book Description
Author: Ian Wills
Publisher: Springer Nature
ISBN: 3030299406
Category : Philosophy
Languages : en
Pages : 255
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Book Description
This book develops a systematic approach to the role of failure in innovation, using the laboratory notebooks of America's most successful inventor, Thomas Edison. It argues that Edison's active pursuit of failure and innovative uses of failure as a tool were crucial to his success. From this the author argues that not only should we expect innovations to fail but that there are good reasons to want them to fail. Using Edison's laboratory notebooks, written as he worked and before he knew the outcome we see the many false starts, wrong directions and failures that he worked through on his way to producing revolutionary inventions. While Edison's strengths in exploiting failure made him the icon of American inventors, they could also be liabilities when he moved from one field to another. Not only is this book of value to readers with an interest in the history of technology and American invention, its insights are important to those who seek to innovate and to those who employ and finance them.
