Pyrrolizidine Alkaloids Health and Safety Guide PDF Download
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Author: International Program on Chemical Safety
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 24
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Book Description
This is a companion volume to Environmental Health Criteria 80: Pyrrolizidine alkaloids. Published by WHO for the International Programme on Chemical Safety, (a collaborative programme of UNEP, ILO and WHO)
Author: International Program on Chemical Safety
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 24
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Book Description
This is a companion volume to Environmental Health Criteria 80: Pyrrolizidine alkaloids. Published by WHO for the International Programme on Chemical Safety, (a collaborative programme of UNEP, ILO and WHO)
Author: Helmut Wiedenfeld
Publisher: Vandenhoeck & Ruprecht
ISBN: 3899714261
Category : Pyrrolizidines
Languages : de
Pages : 145
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Book Description
Pyrrolizidine alkaloids show only minor toxicity in their native state, but are metabolized in the human or animal organisms to carcinogenic, teratogenic and mutagenic compounds, with the precise structure of these compounds being responsible for the metabolic toxification process. Therefore, to be able to evaluate the toxic potential of each alkaloid, it is essential to exactly know the structure of the respective compound. X-ray structure analysis is the appropriate method both for elucidating the structure and for determining other parameters, such as the lengths of the bonds that influence the metabolic process. This book describes the incidence and the process of the intoxication as well as the possibilities to how the substances may reach the organism. In addition, the compounds elucidated by X-ray structure analysis to date are shown in their three-dimensional structure and structure-toxicity relationships are discussed.Pyrrolizidinalkaloide weisen in nativem Zustand nur geringe Toxizität auf, werden jedoch zu kanzerogenen, teratogenen und mutagenen Verbindungen metabolisiert, wenn sie in den menschlichen oder tierischen Organismus gelangen. Der Verlauf dieser Toxifizierung hängt von der konkreten Struktur dieser Stoffe und weiteren Parametern ab. Zur Bestimmung dieser Faktoren stellt die Röntgenstrukturanalyse die geeignete Methode dar. Im vorliegenden Buch werden das Vorkommen, der Ablauf der Toxifizierung und die Möglichkeiten, wie die Stoffe in den Organismus gelangen können, beschrieben. Es werden die bislang durch Röntgenstrukturanalyse vermessenen Verbindungen in ihrer 3D-Struktur aufgefÃ"hrt und Struktur-Toxizitätsbeziehungen diskutiert.
Author: Frauke Gaedcke
Publisher: CRC Press
ISBN: 9780849310232
Category : Health & Fitness
Languages : en
Pages : 208
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Book Description
Herbal medicinal products are becoming more widely accepted as alternatives to medical prescriptions. Many physicians believe that herbal medicinal products are able to beneficially complement or even replace chemical medicines. Recognizing this, European institutions are pushing the harmonization of assessment criteria for herbal medicinal products. However, this kind of reevaluation of herbal medicinal products is combined with increased expectations of physicians, pharmacists, and patients with regard to quality, safety and efficacy. There are often uncertainties about the interpretation of basic terms related to the manufacture and quality of herbal medicinal products. Herbal Medicinal Products clarifies these uncertainties, increasing transparency in the herbal medicinal products market and supporting an adequate scientific discussion related to herbal medicinal products. It offers a complete survey on current scientific knowledge, as well as on legal basic requirements for the development, standardization, and licensing of herbal medicinal products.
Author: L. B. Bull
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 320
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Book Description
Author: A. R. Mattocks
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 424
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Book Description
Author: John Gilbert
Publisher: John Wiley & Sons
ISBN: 1444302299
Category : Technology & Engineering
Languages : en
Pages : 432
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Book Description
Inherent toxicants and processing contaminants are bothnon-essential, bioactive substances whose levels in foods can bedifficult to control. This volume covers both types of compound forthe first time, examining their beneficial as well as theirundesirable effects in the human diet. Chapters have been writtenas individually comprehensive reviews, and topics have beenselected to illustrate recent scientific advances in understandingof the occurrence and mechanism of formation, exposure/riskassessment and developments in the underpinning analyticalmethodology. A wide range of contaminants are examined in detail,including pyrrolizidine alkaloids, glucosinolates, phycotoxins, andmycotoxins. Several process contaminants (eg acrylamide and furan),which are relatively new but which have a rapidly growingliterature, are also covered. The book provides a practical reference for a wide range ofexperts: specialist toxicologists (chemists and food chemists),hygienists, government officials and anyone who needs to be awareof the main issues concerning toxicants and process contaminants infood. It will also be a valuable introduction to the subject forpost-graduate students.
Author: Jeffrey K. Aronson
Publisher: Elsevier
ISBN: 0444537163
Category : Medical
Languages : en
Pages : 7629
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Book Description
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles. Enhanced encyclopedic format with drug monographs now organized alphabetically Completely expanded coverage of each drug, with more than 1,500 drug articles and information on adverse reactions and interactions Clearer, systematic organization of information for easier reading, including case histories to provide perspective on each listing Extensive bibliography with over 40,000 references A must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company
Author: Michael W. Shannon
Publisher: Saunders
ISBN: 9780721606934
Category : Drugs
Languages : en
Pages : 0
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Book Description
This edition is a reference for information related to the clinical management of children and adults whose health has been effected or potentially effected by toxic agents, including drugs, environmental threats, and natural toxins.
Author:
Publisher: Elsevier
ISBN: 0080468845
Category : Medical
Languages : en
Pages : 6448
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Book Description
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Author: Yiu-Chung Wong
Publisher: John Wiley & Sons
ISBN: 1118992725
Category : Technology & Engineering
Languages : en
Pages : 790
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Book Description
Analysis of Food Toxins and Toxicants consists of five sections, providing up-to-date descriptions of the analytical approaches used to detect a range of food toxins. Part I reviews the recent developments in analytical technology including sample pre-treatment and food additives. Part II covers the novel analysis of microbial and plant toxins including plant pyrrolizidine alkaloids. Part III focuses on marine toxins in fish and shellfish. Part IV discusses biogenic amines and common food toxicants, such as pesticides and heavy metals. Part V summarizes quality assurance and the recent developments in regulatory limits for toxins, toxicants and allergens, including discussions on laboratory accreditation and reference materials.
