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Author: David Healy
Publisher: CRC Press
ISBN: 1351409425
Category : Medical
Languages : en
Pages : 665
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Book Description
Create! is a Design and Technology course for Key Stage 3. It provides all the material needed to deliver the demands of the new Key Stage 3 strategy. The course follows the QCA scheme and the materials support ICT requirements. A wide range of differentiated worksheets is available on a customisable CD-ROM. The student books contain clear links to the Key Stage 3 strategy and include design-and-make assignments, product evaluations and practical tasks; each spread opens with objectives to focus the lesson, and ends with a plenary to summarise and evaluate.
Author: David Healy
Publisher: CRC Press
ISBN: 1351409425
Category : Medical
Languages : en
Pages : 665
Get Book Here
Book Description
Create! is a Design and Technology course for Key Stage 3. It provides all the material needed to deliver the demands of the new Key Stage 3 strategy. The course follows the QCA scheme and the materials support ICT requirements. A wide range of differentiated worksheets is available on a customisable CD-ROM. The student books contain clear links to the Key Stage 3 strategy and include design-and-make assignments, product evaluations and practical tasks; each spread opens with objectives to focus the lesson, and ends with a plenary to summarise and evaluate.
Author: David Healy
Publisher: CRC Press
ISBN: 1000161471
Category : Medical
Languages : en
Pages : 613
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Book Description
The Psychopharmacologists 3 completes a trio of interview-based books about the process of therapeutic innovation in clinical psychiatry. David Healy's method is to interview key individuals involved in the discovery and deployment of drugs that have proved useful to psychiatry, and to draw them together within a model of the mechanism and clinical discovery that he uses as an overall framework. These are historical accounts but highly relevant to the clinical psychiatrist of today, emphasising the importance of research, and of the marketing strategies of pharmaceutical companies in formulating disease entities as well as treatments for them.
Author: David Healy
Publisher: CRC Press
ISBN: 9780340761106
Category : Medical
Languages : en
Pages : 624
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Book Description
The Psychopharmacologists 3 completes a trio of interview-based books about the process of therapeutic innovation in clinical psychiatry. David Healy's method is to interview key individuals involved in the discovery and deployment of drugs that have proved useful to psychiatry, and to draw them together within a model of the mechanism and clinical discovery that he uses as an overall framework. These are historical accounts but highly relevant to the clinical psychiatrist of today, emphasising the importance of research, and of the marketing strategies of pharmaceutical companies in formulating disease entities as well as treatments for them.
Author: David Healy
Publisher: Harvard University Press
ISBN: 9780674038455
Category : Medical
Languages : en
Pages : 484
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Book Description
David Healy follows his widely praised study, The Antidepressant Era, with an even more ambitious and dramatic story: the discovery and development of antipsychotic medication. Healy argues that the discovery of chlorpromazine (more generally known as Thorazine) is as significant in the history of medicine as the discovery of penicillin, reminding readers of the worldwide prevalence of insanity within living memory. But Healy tells not of the triumph of science but of a stream of fruitful accidents, of technological discovery leading neuroscientific research, of fierce professional competition and the backlash of the antipsychiatry movement of the 1960s. A chemical treatment was developed for one purpose, and as long as some theoretical rationale could be found, doctors administered it to the insane patients in their care to see if it would help. Sometimes it did, dramatically. Why these treatments worked, Healy argues provocatively, was, and often still is, a mystery. Nonetheless, such discoveries made and unmade academic reputations and inspired intense politicking for the Nobel Prize. Once pharmaceutical companies recognized the commercial potential of antipsychotic medications, financial as well as clinical pressures drove the development of ever more aggressively marketed medications. With verve and immense learning, Healy tells a story with surprising implications in a book that will become the leading scholarly work on its compelling subject.
Author: Marietta Meier
Publisher: Manchester University Press
ISBN: 1526169797
Category : Medical
Languages : en
Pages : 272
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Book Description
The heroic story of the invention of antidepressants is a key part of the psychopharmaceutical turn. On Trial revolves around one of its pioneers, psychiatrist Roland Kuhn, who practiced in Münsterlingen, a state-run psychiatric hospital in Switzerland. Kuhn became famous for the ‘discovery’ of the first antidepressant, Tofranil, and more recently notorious for his numerous trials on often unsuspecting patients. Largely based on the extensive and previously inaccessible sources of Kuhn’s private archive, the book delves into the early days of industry-sponsored clinical research in psychiatry. It examines how the clinic, patients, doctors, nursing staff, corporations, and authorities interacted in the trials. Conducted from the 1940s to 1980s, the Münsterlingen drug trials are historicised and situated in the period’s evolving landscape of experimentation.
Author: Robert A. McArthur
Publisher: Academic Press
ISBN: 0080920403
Category : Medical
Languages : en
Pages : 426
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Book Description
Reward Deficit Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders such as alcohol dependence, nicotine dependence, heroin and cocaine addiction, obesity, and gambling and impulse control disorders. Reward Deficit Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. Reward Deficit Disorders also has a section dedicated to the specifics of the regulatory aspects to abuse liability testing. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the third volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Neurological Disorders is available for purchase individually.
Author: Gregory M. Thomas
Publisher: LSU Press
ISBN: 080714407X
Category : History
Languages : en
Pages : 427
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Book Description
From the outset of World War I, French doctors faced an apparent epidemic of puzzling neurological and psychiatric illnesses among soldiers. As they attempted to understand the causes of these illnesses, doctors organized specialized centers near the front, where they submitted soldiers to swift, humiliating treatments and then returned them to duty. At home, they interned the scores of civilians who succumbed to the war's strains in decrepit asylums or left them to fend for themselves. In Treating the Trauma of the Great War, Gregory M. Thomas explores the psychological effects of the war on French citizens, showing how doctors' understanding of mental illness produced deep, tangible effects in the lives of the men and women who suffered. Doctors vigorously debated the war's role in the genesis of the neuropsychiatric disturbances observed in soldiers and civilians, but most psychiatrists ultimately concluded that mental illnesses appeared primarily in individuals predisposed to disease. Consequently, doctors granted their patients few favors when making decisions about diagnostic labels, treatment regimes, and pension allocations, leaving many to endure illnesses without adequate care or sufficient financial support. In their quest to understand the psychological impact of war, Thomas argues, doctors focused more on demonstrating the capabilities of their medical specialties and serving a state at war than on treating patients. Those aims significantly affected doctors' scientific conclusions, their medical and legal decisions, and their treatment practices. When the war ended, psychiatric reformers used the trauma of war to their advantage, promoting the perception of France as a traumatized nation in need of new psychiatric institutions that could accommodate a large and growing pool of psychologically wounded citizens. Thomas draws on the vast medical literature produced during and after the war, including veterans' journals, parliamentary debates, newspaper articles, and medical administrative reports, infusing his narrative with a vivid human element. Though psychiatrists ultimately failed to raise the status of their specialty, Thomas reveals how the war helped precipitate lasting changes in psychiatric practice.
Author: Joseph Knoll
Publisher: Springer Science & Business Media
ISBN: 3540274340
Category : Medical
Languages : en
Pages : 182
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Book Description
The main message of this monograph is that the appearance of the mammalian brain with the ability to acquire drives ensured the development of social life, and eventually led to the evolution of the human society. This most sophisticated form of organized life on earth is still in the trial and error phase of its development. It seeks to outgrow the myth-directed era of its history and come to its final state, the ration-directed human society.
Author: Lauren Slater
Publisher: Little, Brown
ISBN: 0316370584
Category : Medical
Languages : en
Pages : 361
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Book Description
The explosive story of the discovery and development of psychiatric medications, as well as the science and the people behind their invention, told by a riveting writer and psychologist who shares her own experience with the highs and lows of psychiatric drugs. Although one in five Americans now takes at least one psychotropic drug, the fact remains that nearly seventy years after doctors first began prescribing them, not even their creators understand exactly how or why these drugs work -- or don't work -- on what ails our brains. Lauren Slater's revelatory account charts psychiatry's journey from its earliest drugs, Thorazine and lithium, up through Prozac and other major antidepressants of the present. Blue Dreams also chronicles experimental treatments involving Ecstasy, magic mushrooms, the most cutting-edge memory drugs, placebos, and even neural implants. In her thorough analysis of each treatment, Slater asks three fundamental questions: how was the drug born, how does it work (or fail to work), and what does it reveal about the ailments it is meant to treat? Fearlessly weaving her own intimate experiences into comprehensive and wide-ranging research, Slater narrates a personal history of psychiatry itself. In the process, her powerful and groundbreaking exploration casts modern psychiatry's ubiquitous wonder drugs in a new light, revealing their ability to heal us or hurt us, and proving an indispensable resource not only for those with a psychotropic prescription but for anyone who hopes to understand the limits of what we know about the human brain and the possibilities for future treatments.
Author: Hannah Decker PhD
Publisher: Oxford University Press
ISBN: 0199700303
Category : Medical
Languages : en
Pages : 466
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Book Description
In 1973, the American Psychiatric Association decided to publish a revised edition of their Diagnostic and Statistical Manual (DSM). There was great hope that a new manual would display psychiatry as a scientific field and aid in combating the attacks of an aggressive anti-psychiatry movement that had persisted for more than a decade. The Making of DSM-III® is a book about the manual that resulted in 1980-DSM-III-a far-reaching revisionist work that created a revolution in American psychiatry. Its development precipitated a historic clash between the DSM-III Task Force--a group of descriptive, empirically oriented psychiatrists and psychologists--and the psychoanalysts the Task Force was determined to dethrone from their dominance in American psychiatry. DSM-III also inaugurated an era in which it and the diagnostic manuals that followed played enormous roles in the daily lives of persons and organizations all over the world, for the DSMs have been translated into many languages. The radical revision process was led by the psychiatrist Robert L. Spitzer, a many-talented man of great determination, energy, and tactical skills, arguably the most influential psychiatrist of the second half of the 20th Century. Spitzer created as major a change in descriptive psychiatry and classification as had the renowned German psychiatrist Emil Kraepelin, almost a century earlier. Kraepelin had been the epochal delineator of dementia praecox from manic-depressive illness, the forerunners of modern schizophrenia and bipolar disorder. In her book, Hannah Decker portrays the many internal and external battles that roiled the creation of DSM-III and analyzes both its positive achievements and significant drawbacks. She also astutely explores the deleterious effects of the violent swings in scientific orientation that have dominated psychiatry over the past 200 years and are still alive today. Decker has written a revealing and exciting book that is based on archival sources never before used as well as extensive interviews with the psychiatrists and psychologists who have brought into being the psychiatry we know today.
