Author: Gary M. Williams
Publisher: North Holland
ISBN: 9780444800855
Category : Carcinogenicity testing
Languages : en
Pages : 349
Book Description
The Predictive Value of Short-term Screening Tests in Carcinogenicity Evaluation
The Predictive Value of Short-term Screening Tests in Carcinogenicity Evaluation
Author:
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 349
Book Description
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 349
Book Description
Volume 3: The Predictive Value of Short-Term Screening Tests in Carcinogenicity Evaluation
Author: GM Williams (Ed)
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
The Predictive Value of Short-term Screening Tests in Carcinogenicity Evaluation
Author:
Publisher: Elsevier-North-Holland Biomedical Press
ISBN:
Category : Medical
Languages : en
Pages : 366
Book Description
Publisher: Elsevier-North-Holland Biomedical Press
ISBN:
Category : Medical
Languages : en
Pages : 366
Book Description
The Predicitive of Short-term Screening Tests in Carcinogenicity Evaluation
Author:
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 349
Book Description
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 349
Book Description
Predictive Value of Carcinogenicity Testing in Drug Evaluation
Author: Nordic Council on Medicines
Publisher:
ISBN: 9789186432188
Category : Carcinogenicity testing
Languages : en
Pages : 189
Book Description
Publisher:
ISBN: 9789186432188
Category : Carcinogenicity testing
Languages : en
Pages : 189
Book Description
Long-term and short-term screening Assays for carcinogens
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 426
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 426
Book Description
Carcinogens and Anticarcinogens in the Human Diet
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309053919
Category : Nature
Languages : en
Pages : 434
Book Description
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Publisher: National Academies Press
ISBN: 0309053919
Category : Nature
Languages : en
Pages : 434
Book Description
Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.
Review of Short-term Screening Tests for Mutagens, Toxigens, and Carcinogens
Author: Heath J. Carney
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 78
Book Description
Publisher:
ISBN:
Category : Carcinogenicity testing
Languages : en
Pages : 78
Book Description
Short-Term Test Systems for Detecting Carcinogens
Author: K.H. Norpoth
Publisher: Springer Science & Business Media
ISBN: 3642672027
Category : Medical
Languages : en
Pages : 424
Book Description
The varying cancer incidence from country to country and region to region suggests that en vironmental factors play a considerable role in the aetiology of cancer. Whether these factors in the environment moderate the effect of car cinogenic chemicals or whether they might them selves be carcinogenic is not known at the present time. What is known is that there are various chemicals, both naturally occurring and man-made, which can induce cancer in man. In the Western world estimates vary as to how much cancer is occupational in origin; the figures range from 1% to 40%. It is our feeling that probably about 10% of cancer has a direct oc cupational origin. Nevertheless this number is considerable and it behoves us therefore to identify those chemicals which are carcinogenic and to reduce human exposure. Recent work on the mode of action of carcinogenic chemicals suggests that the majority exert their effect through an activation step to give elec trophilic metabolites. Such metabolites have as a common feature the ability to react with cel lular nucleophiles to give covalently bound products. Such reaction will occur after carcino gen treatment of animals with nucleic acids par ticularly in target organs. It is reaction with nucleic acids that provides the basis of a num ber of short-term tests for carcinogens, since the basic composition of DNA is similar in micro-organisms and in human cells.
Publisher: Springer Science & Business Media
ISBN: 3642672027
Category : Medical
Languages : en
Pages : 424
Book Description
The varying cancer incidence from country to country and region to region suggests that en vironmental factors play a considerable role in the aetiology of cancer. Whether these factors in the environment moderate the effect of car cinogenic chemicals or whether they might them selves be carcinogenic is not known at the present time. What is known is that there are various chemicals, both naturally occurring and man-made, which can induce cancer in man. In the Western world estimates vary as to how much cancer is occupational in origin; the figures range from 1% to 40%. It is our feeling that probably about 10% of cancer has a direct oc cupational origin. Nevertheless this number is considerable and it behoves us therefore to identify those chemicals which are carcinogenic and to reduce human exposure. Recent work on the mode of action of carcinogenic chemicals suggests that the majority exert their effect through an activation step to give elec trophilic metabolites. Such metabolites have as a common feature the ability to react with cel lular nucleophiles to give covalently bound products. Such reaction will occur after carcino gen treatment of animals with nucleic acids par ticularly in target organs. It is reaction with nucleic acids that provides the basis of a num ber of short-term tests for carcinogens, since the basic composition of DNA is similar in micro-organisms and in human cells.