Peritoneal Carcinomatosis: Principles of Management

Peritoneal Carcinomatosis: Principles of Management PDF Author: Paul H. Sugarbaker
Publisher: Springer Science & Business Media
ISBN: 1461312477
Category : Medical
Languages : en
Pages : 434

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Book Description
Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.

Peritoneal Carcinomatosis: Principles of Management

Peritoneal Carcinomatosis: Principles of Management PDF Author: Paul H. Sugarbaker
Publisher: Springer Science & Business Media
ISBN: 1461312477
Category : Medical
Languages : en
Pages : 434

Get Book Here

Book Description
Paul Sugarbaker and his colleagues have persevered in the study and treat ment of peritoneal carcinomatosis. The peritoneal cavity has many unique and incompletely appreciated properties. These properties, coupled with the biologic behavior of many cancers, results in the seeding and growth of these cancers on the peritoneum. Many of these cancers remain localized to the peritoneum only, never metastasizing to other sites. One possible reason for this may be the obstruction of the afferent lymphatics on the undersurface of the diaphragm. The mucopolysaccharides produced by many of these neoplasma are probably viscous enough to obstruct these lymphatics, leading to the syndrome of pseudomyxoma peritonei. Many of the neoplasms taking residence on the peritoneum have extremely long cell-cycle times and are resistant to radiotherapy and many chemotherapeutic agents. How ever, much can be done for these patients - resection of primary cancers, omentectomies to reduce ascites formation, management of recurrent ascites, management of intestinal obstruction, nutritional care, and, hopefully, intraperitoneal chemotherapy. We have reviewed many of these problems in the past [1-7]. Dr. Sugarbaker and his colleagues have organized the current state of knowledge and technology for continuing use. The book provides a basis for thoughtful, prospective research planning. John S. Spratt, M. D. , F. A. C. S. Professor of Surgery The James Graham Brown Cancer Center University of Louisville Louisville, Kentucky References 1. Long RTL, Spratt JS, Dowling E.

CT of the Peritoneum

CT of the Peritoneum PDF Author: Armando Rossi
Publisher: Springer Science & Business Media
ISBN: 9783540414001
Category : Medical
Languages : en
Pages : 442

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Book Description
This elaborately illustrated book, written by two of the leading radiologists in Italy, is devoted entirely to computed tomography of the peritoneum. The case documentation encompasses both common and rare pathological conditions, and is the product of 20 years of painstaking research. Completely original aspects are the description of three-dimensional CT anatomy, with coronal and sagittal reconstructions, and the illustrative schemes of the peritoneum, ligaments, mesentery, peritoneal cavity, and sub- and extraperitoneal structures. This book will be invaluable in improving knowledge of a topic that cannot be treated in detail in general texts on abdominal CT.

The Peritoneum

The Peritoneum PDF Author: Gere S. DiZerega
Publisher: Springer Science & Business Media
ISBN: 1461392357
Category : Medical
Languages : en
Pages : 387

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Book Description
ENTERING ON A CREATIVE AND ENTERPRISING PROJECT, DRS. DIZEREGA and Rodgers have taken an innovative look at the peritoneum. They have provided an interesting, informative, and stimulating text about an organ that is rarely considered independently-usually being thought of only as a part of other organs or organ systems. The peritoneum is an active membrane that serves as both a secretory organ and a structure that modulates diffusion and osmosis. Both of these important functions are described in great detail. The text is divided in classic fashion. The authors first examine the peritoneal anatomy from both macro and cellular viewpoints, during which exploration it becomes clear that what appears simply to be a lacy covering over abdominal organs actually is a complex structure. Fur thermore, during the discussion on its embryologic development the au thors make comprehensible the complexity confronting the student of the peritoneum. The authors then proceed to the practicalities associated with this im portant organ. To surgeons, for example, the key to the peritoneum is understanding the organ's repair mechanism, as it is adhesions formed on the peritoneal surfaces that interfere with the surgeon's hope of success.

Nolph and Gokal's Textbook of Peritoneal Dialysis

Nolph and Gokal's Textbook of Peritoneal Dialysis PDF Author: Ramesh Khanna
Publisher: Springer Science & Business Media
ISBN: 0387789405
Category : Medical
Languages : en
Pages : 927

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Book Description
Nolph and Gokal's Text Book of Peritoneal Dialysis, Third Edition, covers advances made in the field for the past 30 years. During the past two decades, the time during which this therapy has been increasingly utilized, this text has continued to be recognized as the major source of the discipline's base knowledge. The evolution of this text to its newest edition parallels the growth of peritoneal dialysis from Continuous Ambulatory Peritoneal Dialysis in the eighties to the current therapy that encompasses manual and automated therapies with full emphasis on adequacy of dialysis dose. Peritoneal dialysis represents an intracorporeal technique for blood purification. This unique dialysis system represents one of many human attempts to manipulate nature for sustenance of life. The past few years of advances have focused on further improvement of the technique. Areas that have fueled the interest of researchers include: (1) Physiology of high transporters (and the role of genetics and inflammation); (2) Continued debate over the most appropriate adequacy indices (small solute clearances, large solute clearances, clinical assessment etc.); (3) Understanding, preventing and treating the MIA syndrome in PD patients ( including the roles of leptin, and adiponectin); (4) Pathogenesis and newer management strategies of vascular calcification; (5) Continued improvements in infectious complications including peritonitis; (6) Further improvements in catheter technology; (7) Automated techniques; (8) Explaining and correcting PD underutilization; (9) Rationale and applications of newer dialysis solutions; (10) New understanding and approaches to management of osteodystrophy; (11) Refinements in anemia management including new insights in iron metabolism in PD patients; (12) Further definition of indications for PD; (13) The ideal time to initiate dialysis. Newer insight into host defense mechanisms have also made the past decade of advances in the field more meaningful for clinicians. This text also covers the knowledge gained from animal models of peritoneal dialysis. Nolph and Gokal's Textbook of Peritoneal Dialysis, Third Edition is a compilation of the latest knowledge in the field. It cites and describes in great detail, the new discoveries and the evolution of understanding the subject of these discoveries.

Laparoscopic Inguinal Hernia Repair

Laparoscopic Inguinal Hernia Repair PDF Author: Ara Darzi
Publisher: CRC Press
ISBN: 9781899066018
Category : Medical
Languages : en
Pages : 128

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Book Description
The repair and management of inguinal hernias represents a significant part of the general surgeon's workload. It was therefore inevitable that following the success of laparoscopic cholysysectomy, surgeons would develop a procedure for repairing inguinal hernias laparoscopically. This book provides the first comprehensive account of laparoscopic inguinal hernia repair. The Editors' aim has been to give step-by-step guidance to each operative procedure discussed with reference to long term results. One of the biggest problems facing surgeons learning new laparoscopic procedures is an understanding and orientation of basic anatomy when viewed through the laparoscope. This issue is discussed at length with guidance on how to avoid the common pitfalls. Final chapters look at the advantages and disadvantages of the Lichtenstein open mesh hernia repair approach, safety and properties of non-absorbal mesh with the last chapters concentrating on laparoscopic suture repair and the new mini hernia operation.

Diseases of the Abdomen and Pelvis

Diseases of the Abdomen and Pelvis PDF Author: G.K.von Schultess
Publisher: Springer Science & Business Media
ISBN: 8847021413
Category : Medical
Languages : en
Pages : 280

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Book Description
This syllabus provides a wide overview of the latest developments in diagnostic work and intervention in diseases of the abdomen and pelvis. In addition to conventional diagnostic radiology, special procedures such as US, CT, MRI, nuclear medicine and interventional techniques are discussed.

Peritoneal Surface Malignancies

Peritoneal Surface Malignancies PDF Author: Emel Canbay
Publisher: Springer
ISBN: 3319129376
Category : Medical
Languages : en
Pages : 127

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Book Description
This book has been designed to provide the full description of the comprehensive management of peritoneal surface malignancies as a new emerging specialty. Combined treatment of cytoreductive surgery (CRS) and hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) introduced by our leader Paul H. Sugarbaker are performed to treat peritoneal metastases by surgeons all around the world. Therefore this book is focused on detailed surgical anatomy of the peritoneum, preoperative clinical assessment of the peritoneal surface malignancy, patient preparation and operation room equipments, different surgical procedures for CRS and reconstruction, intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) and neoadjuvant intraperitoneal chemotherapy, early postoperative intraperitoneal chemotherapy (EPIC) and molecular basis of peritoneal surface malignancies. The chapter on molecular mechanisms of the formation of peritoneal carcinomatosis provides insight into a rapidly expanding knowledge within this speciality. This book should be valuable for surgical oncologists who deal with multimodal treatment for peritoneal surface malignancies, as well as for the trained peritonectomy surgeons. For the senior surgeons, it will also introduce new techniques and approaches in this field such as dealing with the omental cakes and massive organ involvement that requires multi-organ resection.

The Peritoneum

The Peritoneum PDF Author: Byron Robinson
Publisher:
ISBN:
Category : Peritoneum
Languages : en
Pages : 538

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Book Description


The Anatomy of the Human Peritoneum and Abdominal Cavity

The Anatomy of the Human Peritoneum and Abdominal Cavity PDF Author: George Sumner Huntington
Publisher:
ISBN:
Category : Abdomen
Languages : en
Pages : 592

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Book Description


Treatment of Peritoneal Surface Malignancies

Treatment of Peritoneal Surface Malignancies PDF Author: Angelo Di Giorgio
Publisher: Springer
ISBN: 8847057116
Category : Medical
Languages : en
Pages : 398

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Book Description
This monograph summarizes state of the art knowledge regarding peritoneal surface malignancies, with in-depth description of treatment options and the results achieved to date. It explores the most challenging problems on the basis of the authors’ very extensive clinical experience and examines the most relevant clinical trials. A comprehensive summary is provided of all phase 2 studies (the only available completed studies) and of ongoing and future phase 3 studies. Particular attention is paid to the results of integrated treatment comprising cytoreduction (peritonectomy) and hyperthermic intraperitoneal chemotherapy (HIPEC). Helpful background information is also included on the definition and clinical assessment of each clinical form. The book, drawing on data from the entire Italian experience as well as world literature, will be an outstanding benchmark for health professionals and researchers.