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Author: Donald Earl Henson
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 600
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Book Description
A useful resource for the diagnosis and treatment of the early stages of cancer, this excellent book provides vital information for the early recognition of cancerous lesions. Coverage includes the lymphoid system, the small and large intestine, the central nervous system, soft tissue, bone, neuroblastoma, neuroendocrine, Wilms' tumor, the breast, kidney, and more. New to this edition is coverage of molecular pathology, many new chapters on different body sites, as well as many chapters completely rewritten by eminent authors, and new techniques throughout. Written by top-notch surgical pathologists who have extensive experience in each organ system or tissue area under study.Covers in detail the early stages of human cancer. Detailed discussions of clinical pathological features include information on DNA analysis by flow cytometry and its usefulness in diagnosis and prognosis.
Author: Donald Earl Henson
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 600
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Book Description
A useful resource for the diagnosis and treatment of the early stages of cancer, this excellent book provides vital information for the early recognition of cancerous lesions. Coverage includes the lymphoid system, the small and large intestine, the central nervous system, soft tissue, bone, neuroblastoma, neuroendocrine, Wilms' tumor, the breast, kidney, and more. New to this edition is coverage of molecular pathology, many new chapters on different body sites, as well as many chapters completely rewritten by eminent authors, and new techniques throughout. Written by top-notch surgical pathologists who have extensive experience in each organ system or tissue area under study.Covers in detail the early stages of human cancer. Detailed discussions of clinical pathological features include information on DNA analysis by flow cytometry and its usefulness in diagnosis and prognosis.
Author: Donald Earl Henson
Publisher: W.B. Saunders Company
ISBN:
Category : Medical
Languages : en
Pages : 488
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Book Description
Author: Donald Earl Henson
Publisher: Oxford University Press
ISBN: 9780199771721
Category : Medical
Languages : en
Pages : 868
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Book Description
Many malignant tumors have a morphologically recognizable precursor lesion. As screening and early detection have improved our ability to detect lesions at increasingly earlier stages of growth, an increased number of precancerous lesions are seen by pathologists. Unfortunately, a lack of uniform histologic criteria for precursors found in many organs can make diagnostic interpretation difficult. It is evident that physicians are seeking a better understanding of the genesis and progression of these lesions and their early biology, to provide optimal treatment and patient care. Pathology of Incipient Neoplasia 3E brings together all of the information available on the clinicopathologic features of precancerous lesions, defined to include atypical hyperplasias, in-situ changes, microinvasive or very small cancers in some sites, and other lesions recognized as potential precursors for invasive cancer. In some tissues, benign tumors may serve as precursors to malignant tumors, and therefore these also are considered. Organized by organ, each heavily-illustrated chapter is written by a well-recognized expert, to stress different facets of preneoplasia and minimally invasive tumors in that given tissue. Areas where strides have been made in research on molecular biologic aspects of neoplasia are discussed in conjunction with morphologic parameters. A chapter on salivary glands, and more than 350 color photos interspersed throughout the text, are new to this edition.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 680
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Book Description
Author: Alecsandru Ioan Baba
Publisher:
ISBN: 9789732714577
Category : Electronic books
Languages : en
Pages : 787
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Book Description
Author: Sudhir Srivastava
Publisher: IOS Press
ISBN: 9789051993738
Category : Medical
Languages : en
Pages : 512
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Book Description
This book describes the principles and the application of the existing molecular methodology for the detection of early cancer. Discussion focuses on the molecular changes characterizing preneoplastic lesions; molecular targets for early detection; validation of molecular targets; and new diagnostic technology for early detection. The advantages of molecular detection over current methods are examined, as well as the importance of identifying and characterizing preneoplastic lesions. In addition to the uses of highly specific molecular probes to detect early cancer, this book demonstrates the many ways in which molecular markers serve oncology. While meeting pressing needs in the practice of medicine, molecular detection of early cancer scientifically necessitates a confrontation with the biology of cancer, such as the genetic determinants of progression, regression, dormancy, and invasion. This work not only discusses the diagnostic value of these molecular methods but views their practical benefits against a background of conventional morphology.
Author: Manuel Nistal
Publisher: Springer
ISBN: 3319493647
Category : Medical
Languages : en
Pages : 378
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Book Description
This book presents the morphology of different non-tumoral lesions of the testis. By showing the differential diagnosis of each lesion, it offers clinicians vital support with diagnosis and treatment. The book is divided into seven main parts: genetic and developmental pathology of the testis; infertility; vascular pathology of the testis; inflammatory pathology; pathology of the rete testis and epididymis; pathology of the vaginal tunic and paratesticular structures; and a final part dealing with miscellanea. Each chapter includes carefully selected figures and a variety of diagrams highlighting the main characteristics of a specific lesion to facilitate its diagnosis.Based on the authors’ experience with hundreds of biopsies, surgical specimens and autopsies, the book presents material that has been gathered over the past 40 years, providing an essential tool for pathologists, urologists, andrologists and pediatricians who face diagnostic problems.
Author: Gary J. Kelloff
Publisher: Springer Science & Business Media
ISBN: 1592597688
Category : Medical
Languages : en
Pages : 537
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Book Description
Despite significant advances in cancer treatment and measures of neoplastic progression, drug effect (or early detection, overall cancer incidence has increased, pharmacodynamic markers), and markers that measure cancer-associated morbidity is considerable, and overall prognosis as well as predict responses to specific therapy. cancer survival has remained relatively flat over the past All these biomarkers have the potential to greatly augment several decades (1,2). However, new technology the development of successful chemoprevention therapies, allowing exploration of signal transduction pathways, but two specific types of biomarkers will have the most identification of cancer-associated genes, and imaging of immediate impact on successful chemopreventive drug tissue architecture and molecular and cellular function is development—those that measure the risk of developing increasing our understanding of carcinogenesis and cancer invasive life-threatening disease, and those whose mo- progression. This knowledge is moving the focus of cancer lation can “reasonably predict” clinical benefit and, therapeutics, including cancer preventive treatments, to therefore, serve as surrogate endpoints for later-occurring drugs that take advantage of cellular control mechanisms clinical disease. Thus far, the biomarker that best measures to selectively suppress cancer progression. these two phenomena is intraepithelial neoplasia (IEN) Carcinogenesis is now visualized as a multifocal, because it is a near obligate precursor to cancer.
Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128132582
Category : Medical
Languages : en
Pages : 636
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Book Description
Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
Author: Liang Cheng
Publisher: Wiley-Blackwell
ISBN: 9780470571088
Category : Medical
Languages : en
Pages : 768
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Book Description
The human urinary bladder is subject to a unique and extraordinarily diverse array of congenital, inflammatory, metaplastic, and neoplastic abnormalities. This book provides contemporary, comprehensive, and evidence-based practice information for pathologists, urologists, oncologists, and other medical professionals. In Bladder Pathology, a full spectrum of pathologic conditions that afflict the bladder and urothelium are described and lavishly illustrated. With its emphasis on diagnostic criteria and differential diagnoses, this book is of particular value to practicing pathologists—assisting in the pathologist’s recognition, understanding, and accurate interpretation of the light microscopic findings in bladder specimens. Features and benefits of this new volume include: • 1,741 high-quality, color illustrations and 112 tables to illustrate the wide range of pathologic and clinical features in the urinary tract • An evidence-based approach to diagnosis and patient management for infectious, nonneoplastic, and neoplastic conditions • Recent advances in the molecular genetics of the urinary bladder with discussion of their current or potential impact on diagnosis and personalized patient care • With emphasis on the scientific validation of current diagnostic methods and their direct application in clinical practice, Bladder Pathology is a cutting-edge resource that not only offers comprehensive research and clinical information for practicing surgical pathologists, urologists, oncologists, and their clinical colleagues, but also captures a genuine sense of excitement about recent advances in this vital, ever-evolving field.
