Assessment of Future Scientific Needs for Live Variola Virus

Assessment of Future Scientific Needs for Live Variola Virus PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309173191
Category : Medical
Languages : en
Pages : 126

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Book Description
In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. In 1986, WHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus, one at the Centers for Disease Control and Prevention and the other at the VECTOR laboratory in Siberia. In June 1999, WHO decided to delay the destruction of these stocks. Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies. What further benefits, if any, would likely be gained through the use of variola in research and development efforts related to agent detection, diagnosis, prevention, and treatment. What unique potential benefits, if any, the study of variola would have in increasing our fundamental understanding of the biology, host-agent interactions, pathogenesis, and immune mechanisms of viral diseases.

Assessment of Future Scientific Needs for Live Variola Virus

Assessment of Future Scientific Needs for Live Variola Virus PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309173191
Category : Medical
Languages : en
Pages : 126

Get Book Here

Book Description
In 1980, the World Health Organization (WHO) officially declared that smallpox had been eradicated. In 1986, WHO's international Ad Hoc Committee on Orthopox Virus Infections unanimously recommended destruction of the two remaining official stocks of variola virus, one at the Centers for Disease Control and Prevention and the other at the VECTOR laboratory in Siberia. In June 1999, WHO decided to delay the destruction of these stocks. Informing that decision was Assessment of Future Scientific Needs for Variola Virus, which examines: Whether the sequenced variola genome, vaccinia, and monkey pox virus are adequate for future research or whether the live variola virus itself is needed to assist in the development of antiviral therapies. What further benefits, if any, would likely be gained through the use of variola in research and development efforts related to agent detection, diagnosis, prevention, and treatment. What unique potential benefits, if any, the study of variola would have in increasing our fundamental understanding of the biology, host-agent interactions, pathogenesis, and immune mechanisms of viral diseases.

An Account of the Method and Success of Inoculating the Small-pox, in Boston in New-England

An Account of the Method and Success of Inoculating the Small-pox, in Boston in New-England PDF Author: Cotton Mather
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 56

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Book Description


Scientific and Policy Considerations in Developing Smallpox Vaccination Options

Scientific and Policy Considerations in Developing Smallpox Vaccination Options PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309086043
Category : Medical
Languages : en
Pages : 57

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Book Description
At the World Health Assembly in May 1980, the World Health Organization declared the world free of smallpox. Smallpox vaccination of civilians is now indicated only for laboratory workers directly involved with smallpox or closely related orthopox viruses. However recent questions raised by the terrorist attacks in fall 2001 have renewed concerns about possible outbreaks of smallpox resulting from its use as a biological weapon. In June 2002, the Institute of Medicine convened a public conference to discuss the scientific, clinical, procedural, and administrative aspects of various immunization strategies. Scientific and Policy Considerations in Developing Smallpox Vaccination Options summarizes the presentations and discussions from this workshop.

The Conquest of Smallpox

The Conquest of Smallpox PDF Author: P. E. Razzell
Publisher:
ISBN:
Category : Great Britain
Languages : en
Pages : 298

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Book Description


Pox Americana

Pox Americana PDF Author: Elizabeth A. Fenn
Publisher: Macmillan
ISBN: 9780809078219
Category : History
Languages : en
Pages : 388

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Book Description
A horrifying epidemic of smallpox was sweeping across the Americas when the War of Independence began, and yet little is known about it. Fenn reveals how deeply "variola" affected the outcome of the war in every colony and the lives of everyone in North America. Illustrations.

A Vindication of the New Method of Inoculating the Small-pox Against the Arguments and Objections of Langton and Bromfield ...

A Vindication of the New Method of Inoculating the Small-pox Against the Arguments and Objections of Langton and Bromfield ... PDF Author: Giles Watts
Publisher:
ISBN:
Category :
Languages : en
Pages : 90

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Book Description


Pox

Pox PDF Author: Michael Willrich
Publisher: Penguin
ISBN: 1101476222
Category : History
Languages : en
Pages : 511

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Book Description
The untold story of how America's Progressive-era war on smallpox sparked one of the great civil liberties battles of the twentieth century. At the turn of the last century, a powerful smallpox epidemic swept the United States from coast to coast. The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century. At the dawn of the activist Progressive era and during a moment of great optimism about modern medicine, the government responded to the deadly epidemic by calling for universal compulsory vaccination. To enforce the law, public health authorities relied on quarantines, pesthouses, and "virus squads"-corps of doctors and club-wielding police. Though these measures eventually contained the disease, they also sparked a wave of popular resistance among Americans who perceived them as a threat to their health and to their rights. At the time, anti-vaccinationists were often dismissed as misguided cranks, but Willrich argues that they belonged to a wider legacy of American dissent that attended the rise of an increasingly powerful government. While a well-organized anti-vaccination movement sprang up during these years, many Americans resisted in subtler ways-by concealing sick family members or forging immunization certificates. Pox introduces us to memorable characters on both sides of the debate, from Henning Jacobson, a Swedish Lutheran minister whose battle against vaccination went all the way to the Supreme Court, to C. P. Wertenbaker, a federal surgeon who saw himself as a medical missionary combating a deadly-and preventable-disease. As Willrich suggests, many of the questions first raised by the Progressive-era antivaccination movement are still with us: How far should the government go to protect us from peril? What happens when the interests of public health collide with religious beliefs and personal conscience? In Pox, Willrich delivers a riveting tale about the clash of modern medicine, civil liberties, and government power at the turn of the last century that resonates powerfully today.

Canadian Immunization Guide

Canadian Immunization Guide PDF Author: Canada. Comité consultatif national de l'immunisation
Publisher:
ISBN: 9780660193922
Category : Immunization
Languages : en
Pages : 392

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Book Description
The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

A Summary, Historical and Political, of the First Planting, Progressive Improvements, and Present State of the British Settlements in North-America

A Summary, Historical and Political, of the First Planting, Progressive Improvements, and Present State of the British Settlements in North-America PDF Author: William Douglass
Publisher:
ISBN:
Category : Canada
Languages : en
Pages : 598

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Book Description


Princes and Peasants

Princes and Peasants PDF Author: Donald R. Hopkins
Publisher:
ISBN: 9780226351766
Category : Medical
Languages : en
Pages : 380

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Book Description
Traces the history of the disease of smallpox from its possible origins in prehistoric times to its eradication in 1977