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Author: Barrett Williams
Publisher: Barrett Williams
ISBN:
Category : Health & Fitness
Languages : en
Pages : 130
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Book Description
Unlock the Secrets of the Uncommon Dive into The Mysteries of Rare Diseases Explore the captivating world of rare diseases in a groundbreaking eBook that delves into the intricacies of conditions affecting millions worldwide. "The Mysteries of Rare Diseases" takes you on an enlightening journey through the nuanced and often misunderstood landscape of these enigmatic medical phenomena. Begin your exploration with a look at what truly qualifies as a rare disease and how history has shaped our understanding of these unique health challenges. Discover the profound impact rare diseases have on patients and society, setting the stage for a deeper dive into their genetic roots. Genetic mysteries unravel before your eyes as you examine the dual nature of mutations, the intricacies of gene expression, and groundbreaking advancements in genomic sequencing. Join patients on their arduous journey through the "Diagnostic Odyssey," where symptoms puzzle even seasoned specialists. Experience stories of perseverance and triumph as individuals navigate a labyrinth of tests and medical consultations, seeking a name for their conditions. Witness the dawn of innovative treatments as conventional methods clash with cutting-edge therapies. Explore the promise of precision medicine, experimental breakthroughs, and real-world case studies that showcase the potential of medical innovation. Confront the psychological challenges faced by patients and families. Learn about coping strategies, mental health support, and the power of community networks. The book also examines the crucial policy, advocacy, and awareness efforts shaping the future of rare disease management, as well as the bioinformatics and technological breakthroughs that are revolutionizing diagnosis and treatment. Conclude with inspiring narratives of resilience and hope from the rare disease community, gaining valuable insights and lessons from their powerful stories. For those seeking knowledge, empathy, and a glimpse into the future of medicine, "The Mysteries of Rare Diseases" offers a comprehensive and engaging journey into a world of rare possibilities.
Author: Barrett Williams
Publisher: Barrett Williams
ISBN:
Category : Health & Fitness
Languages : en
Pages : 130
Get Book Here
Book Description
Unlock the Secrets of the Uncommon Dive into The Mysteries of Rare Diseases Explore the captivating world of rare diseases in a groundbreaking eBook that delves into the intricacies of conditions affecting millions worldwide. "The Mysteries of Rare Diseases" takes you on an enlightening journey through the nuanced and often misunderstood landscape of these enigmatic medical phenomena. Begin your exploration with a look at what truly qualifies as a rare disease and how history has shaped our understanding of these unique health challenges. Discover the profound impact rare diseases have on patients and society, setting the stage for a deeper dive into their genetic roots. Genetic mysteries unravel before your eyes as you examine the dual nature of mutations, the intricacies of gene expression, and groundbreaking advancements in genomic sequencing. Join patients on their arduous journey through the "Diagnostic Odyssey," where symptoms puzzle even seasoned specialists. Experience stories of perseverance and triumph as individuals navigate a labyrinth of tests and medical consultations, seeking a name for their conditions. Witness the dawn of innovative treatments as conventional methods clash with cutting-edge therapies. Explore the promise of precision medicine, experimental breakthroughs, and real-world case studies that showcase the potential of medical innovation. Confront the psychological challenges faced by patients and families. Learn about coping strategies, mental health support, and the power of community networks. The book also examines the crucial policy, advocacy, and awareness efforts shaping the future of rare disease management, as well as the bioinformatics and technological breakthroughs that are revolutionizing diagnosis and treatment. Conclude with inspiring narratives of resilience and hope from the rare disease community, gaining valuable insights and lessons from their powerful stories. For those seeking knowledge, empathy, and a glimpse into the future of medicine, "The Mysteries of Rare Diseases" offers a comprehensive and engaging journey into a world of rare possibilities.
Author: Jules J. Berman
Publisher: Academic Press
ISBN: 0124200095
Category : Medical
Languages : en
Pages : 407
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Book Description
Rare Diseases and Orphan Drugs shows that much of what we now know about common diseases has been achieved by studying rare diseases. It proposes that future advances in the prevention, diagnosis, and treatment of common diseases will come as a consequence of our accelerating progress in the field of rare diseases. Understanding the complex steps in the development of common diseases, such as cancer, cardiovascular disease, and metabolic diseases, has proven a difficult problem. Rare diseases, however, are often caused by aberrations of a single gene. In rare diseases, we may study how specific genetic defects can trigger a series of events that lead to the expression of a particular disease. Often, the disease process manifested in a certain rare disease is strikingly similar to the disease process observed in a common disease. This work ties the lessons learned about rare diseases to our understanding of common ones. Chapters covering the number of common diseases are minimized, while rare diseases are introduced as single diseases or as members of diseases classes. After reading this book, readers will appreciate how further research into the rare diseases may lead to new methods for preventing, diagnosing, and treating all diseases, rare or common. - Makes rare diseases relevant to clinicians and researchers by tying lessons learned about the rare diseases to our understanding of the common diseases - Stresses basic pathologic mechanisms that account for human disease (e.g., disorders of cell development, replication, maintenance, function and structure), that can be understood without prior training in pathology - Discusses advanced concepts in molecular biology and genetics in a simple, functional context appropriate for medical trainees and new researchers - Offers insights into how further research into rare diseases may lead to new methods for preventing, diagnosing, and treating all diseases
Author: Dr. Euan Angus Ashley
Publisher: Celadon Books
ISBN: 1250234972
Category : Science
Languages : en
Pages : 221
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Book Description
In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease. Since the Human Genome Project was completed in 2003, the price of genome sequencing has dropped at a staggering rate. It’s as if the price of a Ferrari went from $350,000 to a mere forty cents. Through breakthroughs made by Dr. Ashley’s team at Stanford and other dedicated groups around the world, analyzing the human genome has decreased from a heroic multibillion dollar effort to a single clinical test costing less than $1,000. For the first time we have within our grasp the ability to predict our genetic future, to diagnose and prevent disease before it begins, and to decode what it really means to be human. In The Genome Odyssey, Dr. Ashley details the medicine behind genome sequencing with clarity and accessibility. More than that, with passion for his subject and compassion for his patients, he introduces readers to the dynamic group of researchers and doctor detectives who hunt for answers, and to the pioneering patients who open up their lives to the medical community during their search for diagnoses and cures. He describes how he led the team that was the first to analyze and interpret a complete human genome, how they broke genome speed records to diagnose and treat a newborn baby girl whose heart stopped five times on the first day of her life, and how they found a boy with tumors growing inside his heart and traced the cause to a missing piece of his genome. These patients inspire Dr. Ashley and his team as they work to expand the boundaries of our medical capabilities and to envision a future where genome sequencing is available for all, where medicine can be tailored to treat specific diseases and to decode pathogens like viruses at the genomic level, and where our medical system as we know it has been completely revolutionized.
Author: David Fajgenbaum
Publisher: Ballantine Books
ISBN: 1524799629
Category : Biography & Autobiography
Languages : en
Pages : 266
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Book Description
LOS ANGELES TIMES AND PUBLISHERS WEEKLY BESTSELLER • The powerful memoir of a young doctor and former college athlete diagnosed with a rare disease who spearheaded the search for a cure—and became a champion for a new approach to medical research. “A wonderful and moving chronicle of a doctor’s relentless pursuit, this book serves both patients and physicians in demystifying the science that lies behind medicine.”—Siddhartha Mukherjee, New York Times bestselling author of The Emperor of All Maladies and The Gene David Fajgenbaum, a former Georgetown quarterback, was nicknamed the Beast in medical school, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime. Miraculously, Fajgenbaum survived—only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself. More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide. Praise for Chasing My Cure “A page-turning chronicle of living, nearly dying, and discovering what it really means to be invincible in hope.”—Angela Duckworth, #1 New York Times bestselling author of Grit “[A] remarkable memoir . . . Fajgenbaum writes lucidly and movingly . . . Fajgenbaum’s stirring account of his illness will inspire readers.”—Publishers Weekly
Author: Jules J. Berman
Publisher: Academic Press
ISBN: 0128143940
Category : Medical
Languages : en
Pages : 400
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Book Description
Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution. - Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine - Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine - Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter - Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way - Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field
Author: Alfredo Morabia
Publisher: Columbia University Press
ISBN: 0231168853
Category : Medical
Languages : en
Pages : 298
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Book Description
This book is the principal account of epidemiology’s role in the development of effective measures to identify, prevent, and treat diseases. Throughout history, epidemiologists have challenged conventional knowledge, elucidating mysteries of causality and paving the way for remedies. From the outbreak of the bubonic plague, cholera, and cancer to the search for an effective treatment of AIDS and the origins of Alzheimer’s disease, epidemiological thought has been crucial in shaping our understanding of population health issues. Alfredo Morabia’s lucid retelling sheds new light on the historical triumphs of epidemiological research and allows for contemporary readers, patients, and nontechnical audiences to make sense of the immense amount of health information disseminated by the media. By drawing from both historical and contemporary sources, Morabia provides the reader with the tools to differentiate health beliefs from health knowledge. The book covers important topics, including the H1N1 swine flu epidemic, breast cancer, the effects of aspirin, and the link between cigarettes and lung cancer. Enigmas of Health and Disease is a concise narrative helping patients and health providers develop a more informed relationship.
Author: Robert A. Norman
Publisher: Simon and Schuster
ISBN: 1628734604
Category : Medical
Languages : en
Pages : 244
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Book Description
“Vital Signs,” a popular column featured in Discover Magazine, has long been a favorite of readers, showcasing, each month, fascinating new tales of strange illnesses and diseases that baffle doctors and elude diagnosis. Each tale is true and borders on the unbelievable. It’s no wonder that throughout the years the column has become an unofficial textbook for medical students, interns, doctors, and anyone interested in human illness and staying healthy. Now, physician and “Vital Signs” editor Robert Norman has compiled the very best of the series into an intriguing and suspenseful collection for fans and new readers alike. A young woman carries a baby that wasn’t her own—and wasn’t even a human; Aretha Franklin gives a physician the insight needed to save a life; a modern gynecologist faces an ancient disease. These cases and more, representing a wide variety of unique medical anomalies and life-or-death situations, bring readers to the front lines of the medical fray. Fans of hit medical dramas such as House MD will savor the opportunity to read of the real-life cases that puzzled doctors, the gripping detective work that ensued, and the completely unexpected, often life-saving diagnoses. Discover Magazine’s Vital Signs is a glimpse into the exciting work of real medical professionals, told from their perspective, and revealing that anything can happen in medicine. Readers will never look at a “routine check-up” the same again.
Author: Jason Karlawish
Publisher: St. Martin's Press
ISBN: 1250218748
Category : Health & Fitness
Languages : en
Pages : 269
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Book Description
A definitive and compelling book on one of today's most prevalent illnesses. In 2020, an estimated 5.8 million Americans had Alzheimer’s, and more than half a million died because of the disease and its devastating complications. 16 million caregivers are responsible for paying as much as half of the $226 billion annual costs of their care. As more people live beyond their seventies and eighties, the number of patients will rise to an estimated 13.8 million by 2050. Part case studies, part meditation on the past, present and future of the disease, The Problem of Alzheimer's traces Alzheimer’s from its beginnings to its recognition as a crisis. While it is an unambiguous account of decades of missed opportunities and our health care systems’ failures to take action, it tells the story of the biomedical breakthroughs that may allow Alzheimer’s to finally be prevented and treated by medicine and also presents an argument for how we can live with dementia: the ways patients can reclaim their autonomy and redefine their sense of self, how families can support their loved ones, and the innovative reforms we can make as a society that would give caregivers and patients better quality of life. Rich in science, history, and characters, The Problem of Alzheimer's takes us inside laboratories, patients' homes, caregivers’ support groups, progressive care communities, and Jason Karlawish's own practice at the Penn Memory Center.
Author: Anne Rugari
Publisher: Braughler Books, LLC
ISBN: 9780982218716
Category : Young Adult Nonfiction
Languages : en
Pages : 22
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Book Description
Author: D. T. Max
Publisher: Random House
ISBN: 1588365581
Category : Health & Fitness
Languages : en
Pages : 333
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Book Description
For two hundred years a noble Venetian family has suffered from an inherited disease that strikes their members in middle age, stealing their sleep, eating holes in their brains, and ending their lives in a matter of months. In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass. What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world. In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future. Through exclusive interviews and original archival research, Max explains this story’s connection to human greed and ambition–from the Prussian chemist Justus von Liebig, who made cattle meatier by feeding them the flesh of other cows, to New Guinean natives whose custom of eating the brains of the dead nearly wiped them out. The biologists who have investigated these afflictions are just as extraordinary–for example, Daniel Carleton Gajdusek, a self-described “pedagogic pedophiliac pediatrician” who cracked kuru and won the Nobel Prize, and another Nobel winner, Stanley Prusiner, a driven, feared self-promoter who identified the key protein that revolutionized prion study. With remarkable precision, grace, and sympathy, Max–who himself suffers from an inherited neurological illness–explores maladies that have tormented humanity for centuries and gives reason to hope that someday cures will be found. And he eloquently demonstrates that in our relationship to nature and these ailments, we have been our own worst enemy.
