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Author: André Brack
Publisher: Cambridge University Press
ISBN: 9780521564755
Category : Science
Languages : en
Pages : 432
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Book Description
This 199 book reviews discoveries in astronomy, paleontology, biology and chemistry to help us to understand the likely origin of life on Earth.
Author: André Brack
Publisher: Cambridge University Press
ISBN: 9780521564755
Category : Science
Languages : en
Pages : 432
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Book Description
This 199 book reviews discoveries in astronomy, paleontology, biology and chemistry to help us to understand the likely origin of life on Earth.
Author: David W. Deamer
Publisher:
ISBN: 9781936113040
Category : Science
Languages : en
Pages : 0
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Book Description
Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense research, spanning molecular and cellular biology, organic chemistry, cosmology, geology, and atmospheric science. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive account of the environment of the early Earth and the mechanisms by which the organic molecules present may have self-assembled to form replicating material such as RNA and other polymers. The contributors examine the energetic requirements for this process and focus in particular on the essential role of semi-permeable compartments in containment of primitive genetic systems. Also covered in the book are new synthetic approaches for fabricating cellular systems, the potentially extraterrestrial origin of life's building blocks, and the possibility that life once existed on Mars. Comprising five sections Setting the Stage, Components of First Life, Primitive Systems, First Polymers, and Transition to a Microbial World it is a vital reference for all scientists interested in the origin of life on Earth and the likelihood that it has arisen on other planets
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309042461
Category : Science
Languages : en
Pages : 161
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Book Description
The field of planetary biology and chemical evolution draws together experts in astronomy, paleobiology, biochemistry, and space science who work together to understand the evolution of living systems. This field has made exciting discoveries that shed light on how organic compounds came together to form self-replicating molecules-the origin of life. This volume updates that progress and offers recommendations on research programs-including an ambitious effort centered on Mars-to advance the field over the next 10 to 15 years. The book presents a wide range of data and research results on these and other issues: The biogenic elements and their interaction in the interstellar clouds and in solar nebulae. Early planetary environments and the conditions that lead to the origin of life. The evolution of cellular and multicellular life. The search for life outside the solar system. This volume will become required reading for anyone involved in the search for life's beginnings-including exobiologists, geoscientists, planetary scientists, and U.S. space and science policymakers.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Paul Davies
Publisher: Penguin UK
ISBN: 0141941839
Category : Science
Languages : en
Pages : 366
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Book Description
The origins of life remains one of the great unsolved mysteries of science. Growing evidence suggests that the first organisms lived deep underground, in environments previously thought to be uninhabitable, and that microbes carried inside rocks have travelled between Earth and Mars. But the question remains: how can life spring into being from non-living chemicals? THE FIFTH MIRACLE reveals the remarkable new theories and discoveries that seem set to transform our understanding of life's role in the unfolding drama of the cosmos.
Author: Karl S. Matlin
Publisher: University of Chicago Press
ISBN: 0226819345
Category : Biography & Autobiography
Languages : en
Pages : 367
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Book Description
"The difficulty of reconciling chemical mechanisms with the functions of whole living systems has plagued biologists since the development of cell theory in the nineteenth century. As Karl Matlin argues in Crossing the Boundaries of Life, it is no coincidence that this longstanding knot of scientific inquiry was loosened most meaningfully by the work of a cytologist, the Nobel laureate Günter Blobel. In 1975, using an experimental setup that did not contain any cells at all, Blobel was able to synthesize proteins to theorize how proteins in the cell communicate spatially, an idea he called signal hypothesis. Over the next 20 years, Blobel and other scientists were able to dissect this process into its precise molecular details. For elaborating his signal concept into a process he termed membrane topogenesis-the idea that each protein in the cell is synthesized with an "address" that directs the protein to its correct destination within the cell-Blobel was awarded the Nobel Prize in Physiology or Medicine in 1999. Matlin argues that Blobel's investigative strategy and its subsequent application addressed the fundamental unresolved dilemma that had bedeviled biology from its very beginning, allowing biology to overcome the barrier that had long blocked progress toward mechanistic explanations of life. Crossing the Boundaries of Life thus uses Blobel's research and life story to shed light on the importance of cell biology for twentieth-century science, illustrating how it propelled the development of adjacent disciplines like biochemistry and molecular biology"--
Author: Jan Spitzer
Publisher: MIT Press
ISBN: 0262362597
Category : Science
Languages : en
Pages : 249
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Book Description
A reconceptualization of origins research that exploits a modern understanding of non-covalent molecular forces that stabilize living prokaryotic cells. Scientific research into the origins of life remains exploratory and speculative. Science has no definitive answer to the biggest questions--"What is life?" and "How did life begin on earth?" In this book, Jan Spitzer reconceptualizes origins research by exploiting a modern understanding of non-covalent molecular forces and covalent bond formation--a physicochemical approach propounded originally by Linus Pauling and Max Delbrück. Spitzer develops the Pauling-Delbrück premise as a physicochemical jigsaw puzzle that identifies key stages in life's emergence, from the formation of first oceans, tidal sediments, and proto-biofilms to progenotes, proto-cells and the first cellular organisms.
Author: J. Mayo Greenberg
Publisher: Springer Science & Business Media
ISBN: 9401119368
Category : Science
Languages : en
Pages : 429
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Book Description
This volume contains the lectures presented at the second course of the International School of Space Chemistry held in Erice (Sicily) from October 20 - 30 1991 at the "E. Majorana Centre for Scientific Culture". The course was attended by 58 participants from 13 countries. The Chemistry of Life's Origins is well recognized as one of the most critical subjects of modem chemistry. Much progress has been made since the amazingly perceptive contributions by Oparin some 70 years ago when he first outlined a possible series of steps starting from simple molecules to basic building blocks and ultimate assembly into simple organisms capable of replicating, catalysis and evolution to higher organisms. The pioneering experiments of Stanley Miller demonstrated already forty years ago how easy it could have been to form the amino acids which are critical to living organisms. However we have since learned and are still learning a great deal more about the primitive conditions on earth which has led us to a rethinking of where and how the condition for prebiotic chemical processes occurred. We have also learned a great deal more about the molecular basis for life. For instance, the existence of DNA was just discovered forty years ago.
Author: Michel Morange
Publisher: Harvard University Press
ISBN: 9780674001695
Category : History
Languages : en
Pages : 350
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Book Description
Every day it seems the media focus on yet another new development in biology--gene therapy, the human genome project, the creation of new varieties of animals and plants through genetic engineering. These possibilities have all emanated from molecular biology. A History of Molecular Biology is a complete but compact account for a general readership of the history of this revolution. Michel Morange, himself a molecular biologist, takes us from the turn-of-the-century convergence of molecular biology's two progenitors, genetics and biochemistry, to the perfection of gene splicing and cloning techniques in the 1980s. Drawing on the important work of American, English, and French historians of science, Morange describes the major discoveries--the double helix, messenger RNA, oncogenes, DNA polymerase--but also explains how and why these breakthroughs took place. The book is enlivened by mini-biographies of the founders of molecular biology: Delbrück, Watson and Crick, Monod and Jacob, Nirenberg. This ambitious history covers the story of the transformation of biology over the last one hundred years; the transformation of disciplines: biochemistry, genetics, embryology, and evolutionary biology; and, finally, the emergence of the biotechnology industry. An important contribution to the history of science, A History of Molecular Biology will also be valued by general readers for its clear explanations of the theory and practice of molecular biology today. Molecular biologists themselves will find Morange's historical perspective critical to an understanding of what is at stake in current biological research.
Author: Horst Rauchfuss
Publisher: Springer Science & Business Media
ISBN: 3540788239
Category : Nature
Languages : en
Pages : 354
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Book Description
How did life begin on the early Earth? We know that life today is driven by the universal laws of chemistry and physics. By applying these laws over the past ?fty years, en- mous progress has been made in understanding the molecular mechanisms that are the foundations of the living state. For instance, just a decade ago, the ?rst human genome was published, all three billion base pairs. Using X-ray diffraction data from crystals, we can see how an enzyme molecule or a photosynthetic reaction center steps through its catalytic function. We can even visualize a ribosome, central to all life, translate - netic information into a protein. And we are just beginning to understand how molecular interactions regulate thousands of simultaneous reactions that continuously occur even in the simplest forms of life. New words have appeared that give a sense of this wealth of knowledge: The genome, the proteome, the metabolome, the interactome. But we can’t be too smug. We must avoid the mistake of the physicist who, as the twentieth century began, stated con?dently that we knew all there was to know about physics, that science just needed to clean up a few dusty corners. Then came relativity, quantum theory, the Big Bang, and now dark matter, dark energy and string theory. Similarly in the life sciences, the more we learn, the better we understand how little we really know. There remains a vast landscape to explore, with great questions remaining.
