The Merkel Cell

The Merkel Cell PDF Author: Klaus Baumann
Publisher: Springer Science & Business Media
ISBN: 3662103583
Category : Medical
Languages : en
Pages : 252

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Book Description
Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but their discovery has raised additional questions regarding Merkel cell function. Essential aspects of structure, development and function of normal Merkel cells and Merkel cell carcinoma are presented in short chapters, providing concise and up-to date information on this fascinating cell type.

The Merkel Cell

The Merkel Cell PDF Author: Klaus Baumann
Publisher: Springer Science & Business Media
ISBN: 3662103583
Category : Medical
Languages : en
Pages : 252

Get Book Here

Book Description
Since their first description in 1875, Merkel cells have remained an elusive cell type. Their origin as well as their classification as mechanoreceptors have been a matter of controversy and intense discussion. The peptidergic granules in these cells are suggestive of neuroendocrine functions, but their discovery has raised additional questions regarding Merkel cell function. Essential aspects of structure, development and function of normal Merkel cells and Merkel cell carcinoma are presented in short chapters, providing concise and up-to date information on this fascinating cell type.

Mohs Micrographic Surgery

Mohs Micrographic Surgery PDF Author: Stephen N. Snow
Publisher: Univ of Wisconsin Press
ISBN: 9780299204709
Category : Mohs surgery
Languages : en
Pages : 464

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Book Description
Mohs Micrographic Surgery, an advanced treatment procedure for skin cancer, offers the highest potential for recovery--even if the skin cancer has been previously treated. This procedure is a state-of-the-art treatment in which the physician serves as surgeon, pathologist, and reconstructive surgeon. It relies on the accuracy of a microscope to trace and ensure removal of skin cancer down to its roots. This procedure allows dermatologists trained in Mohs Surgery to see beyond the visible disease and to precisely identify and remove the entire tumor, leaving healthy tissue unharmed. This procedure is most often used in treating two of the most common forms of skin cancer: basal cell carcinoma and squamous cell carcinoma. The cure rate for Mohs Micrographic Surgery is the highest of all treatments for skin cancer--up to 99 percent even if other forms of treatment have failed. This procedure, the most exact and precise method of tumor removal, minimizes the chance of regrowth and lessens the potential for scarring or disfigurement

Non-melanoma Skin Cancer of the Head and Neck

Non-melanoma Skin Cancer of the Head and Neck PDF Author: Faruque Riffat
Publisher: Springer
ISBN: 8132224973
Category : Medical
Languages : en
Pages : 214

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Book Description
Non-melanoma skin cancer is a global public health issue. With an ever-increasing, and ageing, world population coupled with increasing numbers of immunosuppressed individuals the number of patients continues to rise. The head and neck is overwhelmingly the most frequent location for the development of a non-melanoma skin cancer and as such challenges the clinician with its complex anatomy. The importance of maintaining the aesthetics of the face and the function of the anatomy cannot be overstated, yet ultimately it is always the aim of curing a patient with the minimum of morbidity that clinicians strive for. However, the spectrum of presentations and subsequent management varies widely, ranging from patients with the ubiquitous low-risk mid-face basal cell carcinoma to those diagnosed with relatively uncommon but potentially life-threatening high-risk squamous cell carcinomas (e.g. involving metastatic lymph nodes or with perineural invasion present) and Merkel cell carcinomas.

Skin Cancer

Skin Cancer PDF Author: Robert A. Schwartz
Publisher: Springer Science & Business Media
ISBN: 1461237904
Category : Medical
Languages : en
Pages : 683

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Book Description
The skin, uniquely positioned at the interface between the human body and the external world, plays a multifaceted role in the expression of cancer. Primary skin cancer is the most common cancer afflicting mankind and is rising in inci dence, despite the fact that it is often preventable. Besides primary cancer, the skin may show direct and indirect evidence of internal cancer, thus serving as a window to the body for both laymen and physicians alike. In addition, the acces sibility of the skin is useful for the study of carcinogenesis as well as cancer treat ment options. lowe much of my interest in skin cancer to Dr. Leon Goldman, the father of dermatologic laser surgery, and to Dr. Edmund Klein, the father of modern immunotherapy. We, at the Roswell Park Memorial Institute, were indeed for tunate to have a wealth of patients available for study. Many of the illustrations used in this book were of my patients at the Institute, and I kindly thank the fol lowing publications and their respective publishers for allowing me to reuse some of my photographs, most notably: Cancer Medicine (2nd edition), Journal of Surgical Oncology, Journal of the American Academy of Dermatology, Archives of Dermatology, Cancer, and Journal of Dermatologic Surgery and Oncology. We are very fortunate in this work to have some of the world's foremost authorities in their areas as contributors, such as Drs. Zackheim, Lambert, J.W. Trimble, J.R. Trimble, Jackson, Crutcher, Mashberg, Wick, Sidell, F. Helm, G.

Ocular Adnexal Lesions

Ocular Adnexal Lesions PDF Author: Shantha Amrith
Publisher: Springer
ISBN: 9811337985
Category : Medical
Languages : en
Pages : 357

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Book Description
This comprehensive book focuses on eyelid, lacrimal and orbital lesions, covering a wide variety of common and rare diseases and correlating their clinical, radiological and pathological aspects. It presents a large number of illustrative cases, with a discussion of the clinical history, examination, the imaging and pathology findings, differential diagnosis and management along with a take home message for each. Further, it offers clear guidance on the diagnosis and management of orbital and adnexal lesions. This book is a valuable learning tool for residents and trainee fellows in ophthalmology, as well as for trainees in radiology and pathology. It is also relevant to young ophthalmic plastic and reconstructive surgeons, practicing ophthalmologists, radiologists, and pathologists.

HIV/AIDS-Associated Viral Oncogenesis

HIV/AIDS-Associated Viral Oncogenesis PDF Author: Craig Meyers
Publisher: Springer
ISBN: 3030035026
Category : Medical
Languages : en
Pages : 250

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Book Description
One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.

The Merkel Cell

The Merkel Cell PDF Author: Klaus Baumann
Publisher:
ISBN: 9783662103593
Category :
Languages : en
Pages : 264

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Book Description


The American Cancer Society's Oncology in Practice

The American Cancer Society's Oncology in Practice PDF Author: The American Cancer Society
Publisher: John Wiley & Sons
ISBN: 1118517644
Category : Medical
Languages : en
Pages : 727

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Book Description
Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners comprehensively addresses all aspects of clinical management for cancer taking a balanced, authoritative and, -where possible- evidence-based stance and may be used in conjunction with the book, The American Cancer Society's Principles of Oncology: Prevention to Survivorship. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a practical understanding of the field of oncology.

Surgical Oncology Manual

Surgical Oncology Manual PDF Author: Frances C. Wright
Publisher: Springer Nature
ISBN: 3030483630
Category : Medical
Languages : en
Pages : 526

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Book Description
This third edition manual provides a comprehensive, insightful, evidenced-based review of general surgical oncology and serves as a valuable resource for general surgeons in training, practicing general surgeons, and surgical oncologists. The volume describes a multidisciplinary approach that integrates clinical, radiologic, and pathologic data in formulating practical clinical management, and offers a practical approach to the most common situations when treating cancer patients. Each chapter focuses on an individual malignancy and describes the presentation of the malignancy, integrated management based on stage, landmark trials, and suggestions for who to discuss at multidisciplinary cancer conferences. Multiple tables in each chapter provide a concise yet comprehensive summary of the current status of the field. Clinical “pearls” or tips and tricks from high volume surgeons at the University of Toronto are also discussed. The third edition of the Surgical Oncology Manual will serve as a critical resource for general surgeons in training and practicing surgeons dealing with this challenging field.

Emergencies of the Orbit and Adnexa

Emergencies of the Orbit and Adnexa PDF Author: Bipasha Mukherjee
Publisher: Springer
ISBN: 8132218078
Category : Medical
Languages : en
Pages : 484

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Book Description
This handbook on orbital, lacrimal and eyelid emergencies deals with such situations in a practical manner guiding the ophthalmologists in accurate handling and making them more proficient and confident in managing vision and life-threatening emergencies. With 51 chapters and more than 350 images, this book covers all the eye emergencies that generalist and specialist ophthalmologists can expect to come across in their day to day practices. It can be argued that the orbit can no more be called ‘Pandora’s Box’ because of the unpredictable nature of its contents. This perception has changed over the years due to the advent of improved diagnostic, in particular, imaging techniques. However, since medical residency provides very little exposure to orbital and adnexal disorders, most clinicians are inexperienced and unsure about their management. Facing an emergency situation where improper management can rapidly worsen the condition leading to blindness or even death of the patient is every ophthalmologist’s nightmare. The emergent nature of these conditions does not always provide for a leeway to refer these patients to an orbit and oculoplasty specialist, who are few and far between. By the time the patient reaches his destination, his vision maybe irrevocably lost. The legal implications of such mismanagement can be significant too. This book is a quick and essential resource to manage and refer eye emergencies with confidence.