The Man Who Invented the Chromosome

The Man Who Invented the Chromosome PDF Author: Oren Solomon HARMAN
Publisher: Harvard University Press
ISBN: 0674038339
Category : Biography & Autobiography
Languages : en
Pages : 342

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Book Description
Born by mistake, or connivance, to struggling parents in a small Lancashire cotton town in 1903, an uninspired Darlington inadvertently escaped the obscurity of farming life and rose instead, against all odds, to become within a few short years the world's greatest expert on chromosomes, and one of the most penetrating biological thinkers of the twentieth century. Harman follows Darlington's path from bleak prospects to world fame, showing how, within the most miniscule of worlds, he sought answers to the biggest questions--how species originate, how variation occurs, how Nature, both blind and foreboding, random and insightful, makes her way from deep past to unknown future. But Darlington did not stop there: Chromosomes held within their tiny confines untold, dark truths about man and his culture. This passionate conviction led the once famed Darlington down a path of rebuke, isolation, and finally obscurity. As The Man Who Invented the Chromosome unfolds Darlington's forgotten tale--the Nazi atrocities, the Cold War, the crackpot Lysenko, the molecular revolution, eugenics, Civil Rights, the welfare state, the changing views of man's place in nature, biological determinism--all were interconnected. Just as Darlington's work provoked him to ask questions about the link between biology and culture, his life raises fundamental questions about the link between science and society.

The Man Who Invented the Chromosome

The Man Who Invented the Chromosome PDF Author: Oren Solomon HARMAN
Publisher: Harvard University Press
ISBN: 0674038339
Category : Biography & Autobiography
Languages : en
Pages : 342

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Book Description
Born by mistake, or connivance, to struggling parents in a small Lancashire cotton town in 1903, an uninspired Darlington inadvertently escaped the obscurity of farming life and rose instead, against all odds, to become within a few short years the world's greatest expert on chromosomes, and one of the most penetrating biological thinkers of the twentieth century. Harman follows Darlington's path from bleak prospects to world fame, showing how, within the most miniscule of worlds, he sought answers to the biggest questions--how species originate, how variation occurs, how Nature, both blind and foreboding, random and insightful, makes her way from deep past to unknown future. But Darlington did not stop there: Chromosomes held within their tiny confines untold, dark truths about man and his culture. This passionate conviction led the once famed Darlington down a path of rebuke, isolation, and finally obscurity. As The Man Who Invented the Chromosome unfolds Darlington's forgotten tale--the Nazi atrocities, the Cold War, the crackpot Lysenko, the molecular revolution, eugenics, Civil Rights, the welfare state, the changing views of man's place in nature, biological determinism--all were interconnected. Just as Darlington's work provoked him to ask questions about the link between biology and culture, his life raises fundamental questions about the link between science and society.

The Selfish Gene

The Selfish Gene PDF Author: Richard Dawkins
Publisher: Oxford University Press, USA
ISBN: 9780192860927
Category : Medical
Languages : en
Pages : 372

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Book Description
Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science

Francis Galton

Francis Galton PDF Author: Michael Bulmer
Publisher: JHU Press
ISBN: 0801881404
Category : Biography & Autobiography
Languages : en
Pages : 376

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Book Description
If not for the work of his half cousin Francis Galton, Charles Darwin's evolutionary theory might have met a somewhat different fate. In particular, with no direct evidence of natural selection and no convincing theory of heredity to explain it, Darwin needed a mathematical explanation of variability and heredity. Galton's work in biometry—the application of statistical methods to the biological sciences—laid the foundations for precisely that. This book offers readers a compelling portrait of Galton as the "father of biometry," tracing the development of his ideas and his accomplishments, and placing them in their scientific context. Though Michael Bulmer introduces readers to the curious facts of Galton's life—as an explorer, as a polymath and member of the Victorian intellectual aristocracy, and as a proponent of eugenics—his chief concern is with Galton's pioneering studies of heredity, in the course of which he invented the statistical tools of regression and correlation. Bulmer describes Galton's early ambitions and experiments—his investigations of problems of evolutionary importance (such as the evolution of gregariousness and the function of sex), and his movement from the development of a physiological theory to a purely statistical theory of heredity, based on the properties of the normal distribution. This work, culminating in the law of ancestral heredity, also put Galton at the heart of the bitter conflict between the "ancestrians" and the "Mendelians" after the rediscovery of Mendelism in 1900. A graceful writer and an expert biometrician, Bulmer details the eventual triumph of biometrical methods in the history of quantitative genetics based on Mendelian principles, which underpins our understanding of evolution today.

Outsider Scientists

Outsider Scientists PDF Author: Oren Harman
Publisher: University of Chicago Press
ISBN: 022607854X
Category : Science
Languages : en
Pages : 387

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Book Description
Outsider Scientists describes the transformative role played by “outsiders” in the growth of the modern life sciences. Biology, which occupies a special place between the exact and human sciences, has historically attracted many thinkers whose primary training was in other fields: mathematics, physics, chemistry, linguistics, philosophy, history, anthropology, engineering, and even literature. These outsiders brought with them ideas and tools that were foreign to biology, but which, when applied to biological problems, helped to bring about dramatic, and often surprising, breakthroughs. This volume brings together eighteen thought-provoking biographical essays of some of the most remarkable outsiders of the modern era, each written by an authority in the respective field. From Noam Chomsky using linguistics to answer questions about brain architecture, to Erwin Schrödinger contemplating DNA as a physicist would, to Drew Endy tinkering with Biobricks to create new forms of synthetic life, the outsiders featured here make clear just how much there is to gain from disrespecting conventional boundaries. Innovation, it turns out, often relies on importing new ideas from other fields. Without its outsiders, modern biology would hardly be recognizable.

The Theory of the Gene

The Theory of the Gene PDF Author: Thomas Hunt Morgan
Publisher:
ISBN:
Category : Genetics
Languages : en
Pages : 392

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Book Description


Chromosome Woman, Nomad Scientist

Chromosome Woman, Nomad Scientist PDF Author: Savithri Preetha Nair
Publisher: Taylor & Francis
ISBN: 1000649725
Category : Biography & Autobiography
Languages : en
Pages : 643

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Book Description
This is the first in-depth and analytical biography of an Asian woman scientist—Edavaleth Kakkat Janaki Ammal (1897–1984). Using a wide range of archival sources, it presents a dazzling portrait of the twentieth century through the eyes of a pioneering Indian woman scientist, who was highly mobile, and a life that intersected with several significant historical events—the rise of Nazi Germany and World War II, the struggle for Indian Independence, the social relations of science movement, the Lysenko affair, the green revolution, the dawn of environmentalism and the protest movement against a proposed hydro-electric project in the Silent Valley in the 1970s and 1980s. The volume brings into focus her work on mapping the origin and evolution of cultivated plants across space and time, to contribute to a grand history of human evolution, her works published in peer-reviewed Indian and international journals of science, as well as her co-authored work, Chromosome Atlas of Cultivated Plants (1945), considered a bible by practitioners of the discipline. It also looks at her correspondence with major personalities of the time, including political leaders like Jawaharlal Nehru, biologists like Cyril D. Darlington, J. B. S. Haldane and H. H. Bartlett, geographers like Carl Sauer and social activists like Hilda Seligman, who all played significant roles in shaping her world view and her science. A story spanning over North America, Europe and Asia, this biography is a must-have for scholars and researchers of science and technology studies, gender studies, especially those studying women in the sciences, history and South Asian studies. It will also be a delight for the general reader.

The Gene

The Gene PDF Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1476733538
Category : Medical
Languages : en
Pages : 624

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Book Description
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

The Price of Altruism: George Price and the Search for the Origins of Kindness

The Price of Altruism: George Price and the Search for the Origins of Kindness PDF Author: Oren Harman
Publisher: W. W. Norton & Company
ISBN: 0393339998
Category : Biography & Autobiography
Languages : en
Pages : 462

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Book Description
Describes the intellectual journey of eccentric American genius George Price, who tried to answer the evolutionary riddle of why people are nice, and eventually gave away all his belongings and took his own life in a squatter's flat.

Popularizing Science

Popularizing Science PDF Author: Krishna R. Dronamraju
Publisher: Oxford University Press
ISBN: 0199333920
Category : Science
Languages : en
Pages : 385

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Book Description
J.B.S. Haldane (1892-1964) is widely appreciated as one of the greatest and most influential British scientists of the 20th century, making significant contributions to genetics, physiology, biochemistry, biometry, cosmology, and other sciences. More remarkable, then, is the fact that Haldane had no formal qualification in science. He made frequent appearances in the media, making pronouncements on a variety of poignant topics including mining disasters, meteorites, politics, and the economy, and was a popular scientific essay writer. Haldane also was famed for conducting painful experiments on himself, including several instances in which he permanently injured himself. A staunch Marxist and convert to Hinduism, Haldane lived a diverse, lively and interesting life that is still revered by today's science community. A biography of Haldane has not been attempted since 1968, and that book provided an incomplete account of the man's scientific achievement. "The Life and Works of J.B.S. Haldane" serves to fix this glaring omission, providing a complete biographical sketch written by Krishna Dronamraju, one of the last living men to have worked personally with Haldane. A new genre of biographies of 20th-century scientists has come into being, and thus far works have been written about men like Einstein, Oppenheimer, Bernal, Galton, and many more; the inclusion of Haldane within this genre is an absolute necessity. Dronamraju evaluates Haldane's social and political background, as well as his scientific creativity and accomplishments. Haldane embodies a generation of intellectuals who believed and promoted knowledge for its own sake, and that spirit of scientific curiosity and passion is captured in this biography.

Women After All: Sex, Evolution, and the End of Male Supremacy

Women After All: Sex, Evolution, and the End of Male Supremacy PDF Author: Melvin Konner
Publisher: W. W. Norton & Company
ISBN: 039324654X
Category : Science
Languages : en
Pages : 293

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Book Description
“A sparkling, thought-provoking account of sexual differences. Whether you’re a man or a woman, you’ll find his conclusions gripping.”—Jared Diamond There is a human genetic fluke that is surprisingly common, due to a change in a key pair of chromosomes. In the normal condition the two look the same, but in this disorder one is malformed and shrunken beyond recognition. The result is a shortened life span, higher mortality at all ages, an inability to reproduce, premature hair loss, and brain defects variously resulting in attention deficit, hyperactivity, conduct disorder, hypersexuality, and an enormous excess of both outward and self-directed aggression. It is called maleness. Melvin Konner traces the arc of evolution to explain the relationships between women and men. With patience and wit he explores the knotty question of whether men are necessary in the biological destiny of the human race. He draws on multiple, colorful examples from the natural world—such as the mating habits of the octopus, black widow, angler fish, and jacana—and argues that maleness in humans is hardly necessary to the survival of the species. In characteristically humorous and engaging prose, Konner sheds light on our biologically different identities, while noting the poignant exceptions that challenge the male/female divide. We meet hunter-gatherers such as those in Botswana, whose culture gave women a prominent place, invented the working mother, and respected women’s voices around the fire. Recent human history has upset this balance, as a dense world of war fostered extreme male dominance. But our species has been recovering over the past two centuries, and an unstoppable move toward equality is afoot. It will not be the end of men, but it will be the end of male supremacy and a better, wiser world for women and men alike.