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Author: Fra Angelico
Publisher: Legare Street Press
ISBN: 9781016515245
Category :
Languages : en
Pages : 0
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Book Description
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Author: Fra Angelico
Publisher: Legare Street Press
ISBN: 9781016515245
Category :
Languages : en
Pages : 0
Get Book Here
Book Description
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Author: Daniele Focosi
Publisher: Springer Nature
ISBN: 3030873242
Category : Medical
Languages : en
Pages : 140
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Book Description
This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.
Author: Wulfram Gerstner
Publisher: Cambridge University Press
ISBN: 9780521890793
Category : Computers
Languages : en
Pages : 498
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Book Description
Neurons in the brain communicate by short electrical pulses, the so-called action potentials or spikes. How can we understand the process of spike generation? How can we understand information transmission by neurons? What happens if thousands of neurons are coupled together in a seemingly random network? How does the network connectivity determine the activity patterns? And, vice versa, how does the spike activity influence the connectivity pattern? These questions are addressed in this 2002 introduction to spiking neurons aimed at those taking courses in computational neuroscience, theoretical biology, biophysics, or neural networks. The approach will suit students of physics, mathematics, or computer science; it will also be useful for biologists who are interested in mathematical modelling. The text is enhanced by many worked examples and illustrations. There are no mathematical prerequisites beyond what the audience would meet as undergraduates: more advanced techniques are introduced in an elementary, concrete fashion when needed.
Author: Colin Mason
Publisher: Routledge
ISBN: 1136555110
Category : Law
Languages : en
Pages : 256
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Book Description
The clock is relentlessly ticking! Our world teeters on a knife-edge between a peaceful and prosperous future for all, and a dark winter of death and destruction that threatens to smother the light of civilization. Within 30 years, in the 2030 decade, six powerful 'drivers' will converge with unprecedented force in a statistical spike that could tear humanity apart and plunge the world into a new Dark Age. Depleted fuel supplies, massive population growth, poverty, global climate change, famine, growing water shortages and international lawlessness are on a crash course with potentially catastrophic consequences. In the face of both doomsaying and denial over the state of our world, Colin Mason cuts through the rhetoric and reams of conflicting data to muster the evidence to illustrate a broad picture of the world as it is, and our possible futures. Ultimately his message is clear; we must act decisively, collectively and immediately to alter the trajectory of humanity away from catastrophe. Offering over 100 priorities for immediate action, The 2030 Spike serves as a guidebook for humanity through the treacherous minefields and wastelands ahead to a bright, peaceful and prosperous future in which all humans have the opportunity to thrive and build a better civilization. This book is powerful and essential reading for all people concerned with the future of humanity and planet earth.
Author: Stephen E. Ambrose
Publisher: Simon and Schuster
ISBN: 9780743203173
Category : Business & Economics
Languages : en
Pages : 468
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Book Description
The story of the men who build the transcontinental railroad in the 1860's.
Author:
Publisher:
ISBN:
Category : Canada
Languages : en
Pages : 500
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Book Description
Author: Tom Eisenmann
Publisher: Currency
ISBN: 0593137027
Category : Business & Economics
Languages : en
Pages : 370
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Book Description
If you want your startup to succeed, you need to understand why startups fail. “Whether you’re a first-time founder or looking to bring innovation into a corporate environment, Why Startups Fail is essential reading.”—Eric Ries, founder and CEO, LTSE, and New York Times bestselling author of The Lean Startup and The Startup Way Why do startups fail? That question caught Harvard Business School professor Tom Eisenmann by surprise when he realized he couldn’t answer it. So he launched a multiyear research project to find out. In Why Startups Fail, Eisenmann reveals his findings: six distinct patterns that account for the vast majority of startup failures. • Bad Bedfellows. Startup success is thought to rest largely on the founder’s talents and instincts. But the wrong team, investors, or partners can sink a venture just as quickly. • False Starts. In following the oft-cited advice to “fail fast” and to “launch before you’re ready,” founders risk wasting time and capital on the wrong solutions. • False Promises. Success with early adopters can be misleading and give founders unwarranted confidence to expand. • Speed Traps. Despite the pressure to “get big fast,” hypergrowth can spell disaster for even the most promising ventures. • Help Wanted. Rapidly scaling startups need lots of capital and talent, but they can make mistakes that leave them suddenly in short supply of both. • Cascading Miracles. Silicon Valley exhorts entrepreneurs to dream big. But the bigger the vision, the more things that can go wrong. Drawing on fascinating stories of ventures that failed to fulfill their early promise—from a home-furnishings retailer to a concierge dog-walking service, from a dating app to the inventor of a sophisticated social robot, from a fashion brand to a startup deploying a vast network of charging stations for electric vehicles—Eisenmann offers frameworks for detecting when a venture is vulnerable to these patterns, along with a wealth of strategies and tactics for avoiding them. A must-read for founders at any stage of their entrepreneurial journey, Why Startups Fail is not merely a guide to preventing failure but also a roadmap charting the path to startup success.
Author: Willa Cather
Publisher: Modernista
ISBN: 9181080794
Category :
Languages : en
Pages : 188
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Book Description
When the young Swedish-descended Alexandra Bergson inherits her father's farm in Nebraska, she must transform the land from a wind-swept prairie landscape into a thriving enterprise. She dedicates herself completely to the land—at the cost of great sacrifices. O Pioneers! [1913] is Willa Cather's great masterpiece about American pioneers, where the land is as important a character as the people who cultivate it. WILLA CATHER [1873-1947] was an American author. After studying at the University of Nebraska, she worked as a teacher and journalist. Cather's novels often focus on settlers in the USA with a particular emphasis on female pioneers. In 1923, she was awarded the Pulitzer Prize for the novel One of Ours, and in 1943, she was elected to the American Academy of Arts and Sciences.
Author:
Publisher:
ISBN:
Category : Academic libraries
Languages : en
Pages : 554
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Book Description
Author: Ana Raquel Minian
Publisher: Harvard University Press
ISBN: 067491998X
Category : History
Languages : en
Pages : 189
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Book Description
Frederick Jackson Turner Award Finalist Winner of the David Montgomery Award Winner of the Theodore Saloutos Book Award Winner of the Betty and Alfred McClung Lee Book Award Winner of the Frances Richardson Keller-Sierra Prize Winner of the Américo Paredes Book Award “A deeply humane book.” —Mae Ngai, author of Impossible Subjects “Necessary and timely...A valuable text to consider alongside the current fight for DACA, the border concentration camps, and the unending rhetoric dehumanizing Mexican migrants.” —PopMatters “A deep dive into the history of Mexican migration to and from the United States.” —PRI’s The World In the 1970s, the Mexican government decided to tackle rural unemployment by supporting the migration of able-bodied men. Millions of Mexican men crossed into the United States to find work. They took low-level positions that few Americans wanted and sent money back to communities that depended on their support. They periodically returned to Mexico, living their lives in both countries. After 1986, however, US authorities disrupted this back-and-forth movement by strengthening border controls. Many Mexican men chose to remain in the United States permanently for fear of not being able to come back north if they returned to Mexico. For them, the United States became a jaula de oro—a cage of gold. Undocumented Lives tells the story of Mexican migrants who were compelled to bring their families across the border and raise a generation of undocumented children.
