The Human Teratomas

The Human Teratomas PDF Author: Ivan Damjanov
Publisher: Springer Science & Business Media
ISBN: 1461256283
Category : Medical
Languages : en
Pages : 369

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Book Description

The Human Teratomas

The Human Teratomas PDF Author: Ivan Damjanov
Publisher: Springer Science & Business Media
ISBN: 1461256283
Category : Medical
Languages : en
Pages : 369

Get Book Here

Book Description


Teratomas: New Insights for the Healthcare Professional: 2011 Edition

Teratomas: New Insights for the Healthcare Professional: 2011 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1464908478
Category : Medical
Languages : en
Pages : 42

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Book Description
Teratomas: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Teratomas in a compact format. The editors have built Teratomas: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Teratomas in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Teratomas: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Urological Pathology

Urological Pathology PDF Author: Mahul B. Amin
Publisher: Lippincott Williams & Wilkins
ISBN: 1469857960
Category : Medical
Languages : en
Pages : 2443

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Book Description
Knowledge in the field of urologic pathology is growing at an explosive pace. Today’s pathologists, specialists, and residents require a comprehensive and authoritative text that examines the full range of urological diseases and their diagnosis. Written by recognized leaders and educators in the field, the text provides readers with a detailed understanding of all diagnostic aspects of urological disease. Inside this unique resource, readers will explore a broad spectrum of practical information—including etiology, diagnostic criteria, molecular markers, differential diagnosis, ancillary tests, and clinical management. This is sure to be the new definitive text for urological pathology!

Vascular Development

Vascular Development PDF Author: Derek J. Chadwick
Publisher: John Wiley & Sons
ISBN: 0470319429
Category : Science
Languages : en
Pages : 260

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Book Description
The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

Handbook of Pediatric Surgery

Handbook of Pediatric Surgery PDF Author: Chandrasen K. Sinha
Publisher: Springer Science & Business Media
ISBN: 1848821328
Category : Medical
Languages : en
Pages : 464

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Book Description
Although pediatric surgery is a distinct and evolving specialty, it still remains an integral part of most general surgical and paediatric medical practice. Nevertheless, surgery in children does differ from adult practice in various fundamental ways, and there are key physiological and anatomical differences that constantly need underlining. Progress and improvement in outcome has also been rapid but it is sometimes difficult for practitioners to keep themselves up-to-date with the usual surgical or paediatric text books. This book will give a concise overview of all important topics and is designed to provide information in order to recognise the common surgical conditions; namely typical symptoms and signs, investigation and then treatment management. It will also provide an anatomical and physiological background to aid understanding, in addition to emphasising logical, and where possible, evidence-based practice by the use of flow charts, tables and algorithms. Authored by an international range of leading contributors, this is the first book of its kind to offer comprehensive coverage to this topic in a quick reference, pocket-book format.

Manipulating the Mouse Embryo

Manipulating the Mouse Embryo PDF Author: Andras Nagy
Publisher: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press
ISBN:
Category : Science
Languages : en
Pages : 784

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Book Description
Provides background information and detailed protocols for developing a mouse colony and using the animals in transgenic and gene-targeting experiments. The protocols list the animals, equipment, and reagents required and step-by-step procedures. Topics include in vitro culture of preimplantation embryos, surgical procedures, the production of chimeras, and the analysis of genome alterations. The third edition adds protocols for cloning mice, modifying embryonic stem cells, intracytoplasmic sperm injection, and cryopreservation of embryos.

Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309170427
Category : Science
Languages : en
Pages : 112

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Book Description
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Defining The Teratoma as a Model for Multi-Lineage Human Development

Defining The Teratoma as a Model for Multi-Lineage Human Development PDF Author: Daniella Nicole McDonald
Publisher:
ISBN:
Category :
Languages : en
Pages : 192

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Book Description
We propose that the teratoma, a recognized standard for validating pluripotency in stem cells, could be a promising platform for studying human developmental processes. Performing single cell RNA-seq of 179,632 cells across 23 teratomas from 4 cell lines, we found teratomas reproducibly contain approximately 20 cell types across all 3 germ layers, the inter-teratoma cell type heterogeneity was comparable to organoid systems, and that the teratoma gut and brain cell types correspond well to similar fetal cell types. Cellular barcoding confirmed that injected stem cells robustly engraft and contribute to all lineages. Using pooled CRISPR-Cas9 knockout screens, we showed that teratomas can simultaneously assay the effects of genetic perturbations across all germ layers. Additionally, we demonstrated teratomas can be enriched for specific lineages via a genetic or materials approach. We either molecularly sculpted via miRNA-regulated suicide gene expression or assayed teratomas under multiple matrix conditions. Taken together, the teratoma is a promising platform for modeling multi-lineage development, pan-tissue functional genetic screening, and tissue engineering.

An Illustrated Guide to Pediatric Surgery

An Illustrated Guide to Pediatric Surgery PDF Author: Ahmed H. Al-Salem
Publisher: Springer
ISBN: 331906665X
Category : Medical
Languages : en
Pages : 589

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Book Description
Written in a simple point by point style for ease of use, this volume covers all aspects of pediatric surgery with emphasis on important points for diagnosis and management. Each chapter covers a topic with emphasis on the most common conditions in neonatal and general pediatric surgery. The text is well illustrated with clinical, operative, radiological, and histopathological color figures and illustrations. The book also presents some of the rare conditions encountered in pediatric surgery, as well as common pediatric urology conditions. An Illustrated Guide to Pediatric Surgery is a useful reference to pediatric surgeons, specialists, fellows and residents, as well as general surgeons, pediatricians, neonatologists, medical students and interns interested in pediatric surgery.

Diagnosis and Management of Ovarian Disorders

Diagnosis and Management of Ovarian Disorders PDF Author: Albert Altchek
Publisher: Elsevier
ISBN: 008049451X
Category : Medical
Languages : en
Pages : 595

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Book Description
This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine