The Origins of Human Disease

The Origins of Human Disease PDF Author: Thomas McKeown
Publisher: Wiley-Blackwell
ISBN: 9780631179382
Category : Social Science
Languages : en
Pages : 240

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Book Description
This book is a history of the diseases of humankind and their causes from earliest times to the present day. It is a tour de force drawing upon the author's extensive work on the history of infection, as well upon evidence drawn from archaeology, history and demography.

The Origins of Human Disease

The Origins of Human Disease PDF Author: Thomas McKeown
Publisher: Wiley-Blackwell
ISBN: 9780631179382
Category : Social Science
Languages : en
Pages : 240

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Book Description
This book is a history of the diseases of humankind and their causes from earliest times to the present day. It is a tour de force drawing upon the author's extensive work on the history of infection, as well upon evidence drawn from archaeology, history and demography.

Precision Medicine and the Reinvention of Human Disease

Precision Medicine and the Reinvention of Human Disease PDF Author: Jules J. Berman
Publisher: Academic Press
ISBN: 0128143940
Category : Medical
Languages : en
Pages : 400

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Book Description
Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution. - Clarifies the foundational concepts of Precision Medicine, distinguishing this field from its predecessors such as genomics, pharmacogenetics, and personalized medicine - Gathers the chief conceptual advances in the fields of genetics, pathology, and bioinformatics, and synthesizes a coherent narrative for the field of Precision Medicine - Delivers its message in plain language, and in a relaxed, conversational writing style, making it easy to understand the complex subject matter - Guides the reader through a coherent and logical narrative, gradually providing expertise and skills along the way - Covers the importance of data sharing in Precision Medicine, and the many data-related challenges that confront this fragile new field

Essentials of Human Disease

Essentials of Human Disease PDF Author: Leonard V. Crowley
Publisher: Jones & Bartlett Publishers
ISBN: 1449643892
Category : Diseases
Languages : en
Pages : 573

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Book Description


Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease PDF Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0124159125
Category : Science
Languages : en
Pages : 1109

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Book Description
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. - Organized by disease orientation for ease of searchability - Provides information on locating resources, animal alternatives and animal ethics - Covers a broad range of animal models used in research for human disease

Viruses and Human Disease

Viruses and Human Disease PDF Author: Ellen G. Strauss
Publisher: Elsevier
ISBN: 0080553168
Category : Medical
Languages : en
Pages : 476

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Book Description
Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss' virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. - Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information - Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia - Further reading sections at the end of each chapter make it easy find key references - World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text

Epigenetics in Human Disease

Epigenetics in Human Disease PDF Author: Trygve Tollefsbol
Publisher: Academic Press
ISBN: 0123884160
Category : Medical
Languages : en
Pages : 617

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Book Description
Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Crowley's An Introduction to Human Disease

Crowley's An Introduction to Human Disease PDF Author: Reisner
Publisher: Jones & Bartlett Publishers
ISBN: 1284050238
Category : Health & Fitness
Languages : en
Pages : 849

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Book Description
Preceded by An introduction to human disease / Leonard V. Crowley. 9th ed. c2013.

Human Disease and Health Promotion

Human Disease and Health Promotion PDF Author: Leslie Beale
Publisher: John Wiley & Sons
ISBN: 0470589086
Category : Medical
Languages : en
Pages : 480

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Book Description
The essential tools and methodologies for real-world patient education Human Disease and Health Promotion offers a comprehensive introduction to health advocacy and patient education in a real-world context. Covering the epidemiology and pathology of major communicable and non-communicable diseases, this book details up-to-date health promotion strategies and communication approaches designed to engage diverse populations. These methodologies can inform health promotion efforts. You'll learn how to partner with the patient to navigate healthcare systems and services and how to manage the relationship to avoid patient dependence and advocate burn-out. An extensive guide to common diseases includes details on mechanism, treatment, epidemiology, pathology, and attendant psychosocial implications, and prevention and control are emphasized to the degree that the patient has the capacity to obtain, process, and understand the information and services needed to make appropriate health decisions. Rich in examples, tools, and exercises, this text includes access to a downloadable workbook that provides additional exercises to reinforce concepts and build essential practical skills. Public health education and advocacy is an enormous undertaking with many variables. This book helps provides a real-world picture of the depth and breadth of the field, with clear guidance toward current theory and practice. Apply current health literacy theories and participatory patient education strategies Design, implement, and evaluate programs targeting various groups Analyze and apply new technologies in patient education and health advocacy Understand the mechanisms, treatments, and epidemiology of common diseases Nine out of ten adults may lack the skills needed to manage their health and prevent disease, and over half find it a challenge to self-manage chronic diseases and use health services appropriately. Human Disease and Health Promotion helps you develop your role as health educator and advocate so you can connect patients with the care and information they need.

DNA Replication and Human Disease

DNA Replication and Human Disease PDF Author: Melvin L. DePamphilis
Publisher: CSHL Press
ISBN: 0879697660
Category : Medical
Languages : en
Pages : 814

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Book Description
At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed. At least 160 proteins are involved in replicating the human genome, and at least 40 diseases are caused by aberrant DNA replication, 35 by mutations in genes required for DNA replication or repair, 7 by mutations generated during mitochondrial DNA replication, and more than 40 by DNA viruses. Consequently, a growing number of therapeutic drugs are targeted to DNA replication proteins. This authoritative volume provides a rich source of information for researchers, physicians, and teachers, and will stimulate thinking about the relevance of DNA replication to human disease.

What You Need to Know about Infectious Disease

What You Need to Know about Infectious Disease PDF Author: Madeline Drexler
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description