Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: World Health Organization
ISBN: 9789283201502
Category : Carcinogens
Languages : en
Pages : 0
Book Description
This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.
Some Organophosphate Insecticides and Herbicides
Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: World Health Organization
ISBN: 9789283201502
Category : Carcinogens
Languages : en
Pages : 0
Book Description
This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.
Publisher: World Health Organization
ISBN: 9789283201502
Category : Carcinogens
Languages : en
Pages : 0
Book Description
This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.
The Herbicide Glyphosate
Author: E. Grossbard
Publisher: Butterworth-Heinemann
ISBN:
Category : Technology & Engineering
Languages : nl
Pages : 520
Book Description
Literatuuronderzoek betreffende herbicide glyfosaat, met aandacht voor de chemie; werkingsmechanisme bij zowel onkruiden als gewassen; werkzaamheid in diverse gewassen; gevolgen voor het milieu (inclusief non-target organismen) en de toepassingsmethodiek
Publisher: Butterworth-Heinemann
ISBN:
Category : Technology & Engineering
Languages : nl
Pages : 520
Book Description
Literatuuronderzoek betreffende herbicide glyfosaat, met aandacht voor de chemie; werkingsmechanisme bij zowel onkruiden als gewassen; werkzaamheid in diverse gewassen; gevolgen voor het milieu (inclusief non-target organismen) en de toepassingsmethodiek
Glyphosate Resistance in Crops and Weeds
Author: Vijay K. Nandula
Publisher: John Wiley & Sons
ISBN: 1118043545
Category : Science
Languages : en
Pages : 258
Book Description
New technologies are becoming available for managing glyphosate resistant (GR) weeds and reducing their spread. GR crop technology has revolutionized crop production in the developed world and the benefits are gradually spilling over to the developing world. In order to sustain an effective, environmentally safe herbicide such as glyphosate and the GR crop technology well in to the future, it is imperative that the issue of GR weeds be comprehensively understood. This book provides such an essential, up-to-date source of information on glyphosate resistance for researchers, extension workers, land managers, government personnel, and other decision makers. Provides comprehensive coverage of the intensely studied topic of glyphosate resistant (GR) in crops Details the development of glyphosate resistance and how to detect and manage the problem in crops Helps standardize global approaches to glyphosate resistance Encompasses interdisciplinary approaches in chemistry, weed science, biochemistry, plant physiology, plant biotechnology, genetics, ecology Includes a chapter on economic analysis of GR impact on crops
Publisher: John Wiley & Sons
ISBN: 1118043545
Category : Science
Languages : en
Pages : 258
Book Description
New technologies are becoming available for managing glyphosate resistant (GR) weeds and reducing their spread. GR crop technology has revolutionized crop production in the developed world and the benefits are gradually spilling over to the developing world. In order to sustain an effective, environmentally safe herbicide such as glyphosate and the GR crop technology well in to the future, it is imperative that the issue of GR weeds be comprehensively understood. This book provides such an essential, up-to-date source of information on glyphosate resistance for researchers, extension workers, land managers, government personnel, and other decision makers. Provides comprehensive coverage of the intensely studied topic of glyphosate resistant (GR) in crops Details the development of glyphosate resistance and how to detect and manage the problem in crops Helps standardize global approaches to glyphosate resistance Encompasses interdisciplinary approaches in chemistry, weed science, biochemistry, plant physiology, plant biotechnology, genetics, ecology Includes a chapter on economic analysis of GR impact on crops
Glyphosate
Author: John E. Franz
Publisher:
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 688
Book Description
Glyphosate is a popular global post-emergent perennial herbicide. This volume is a comprehensive review of glyphosate's history, properties, chemistry, biology, formulation, technology, enzymology, and structure/activity relationship. The discussion covers glyphosate's unique environmental properties, broad range of application, soil inactivity, soil and plant metabolism, low toxicity, and uptake and transport in plants. It also covers the syntheses of hundreds of analogs and derivatives and clarifies glyphosate's molecular mode of action and its effect on the target enzyme EPSP synthase.
Publisher:
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 688
Book Description
Glyphosate is a popular global post-emergent perennial herbicide. This volume is a comprehensive review of glyphosate's history, properties, chemistry, biology, formulation, technology, enzymology, and structure/activity relationship. The discussion covers glyphosate's unique environmental properties, broad range of application, soil inactivity, soil and plant metabolism, low toxicity, and uptake and transport in plants. It also covers the syntheses of hundreds of analogs and derivatives and clarifies glyphosate's molecular mode of action and its effect on the target enzyme EPSP synthase.
Sustainable Agriculture Reviews
Author: Eric Lichtfouse
Publisher: Springer
ISBN: 3319267779
Category : Technology & Engineering
Languages : en
Pages : 401
Book Description
This book features articles that analyze current agricultural issues and knowledge. It also proposes novel, environmentally friendly solutions that are based on integrated information from such fields as agronomy, soil science, molecular biology, chemistry, toxicology, ecology, economics and the social sciences.Coverage examines ways to produce food and energy in a sustainable way for humans and their children. Inside, readers will find articles that explore climate change, increasing food and fuel prices, poor-nation starvation, rich-nation obesity, water pollution, soil erosion, fertility loss, pest control and biodiversity depletion. Instead of solving problems using the classical painkiller approach, which seeks to limit negative impacts, sustainable agriculture treats challenges at their source. Because most societal issues are in fact intertwined, global, and fast-developing, sustainable agriculture will bring solutions that have the potential to build a more peaceful world. This book will help scientists, decision-makers, professors, farmers and politicians build safer agriculture, energy and food systems for future generations.
Publisher: Springer
ISBN: 3319267779
Category : Technology & Engineering
Languages : en
Pages : 401
Book Description
This book features articles that analyze current agricultural issues and knowledge. It also proposes novel, environmentally friendly solutions that are based on integrated information from such fields as agronomy, soil science, molecular biology, chemistry, toxicology, ecology, economics and the social sciences.Coverage examines ways to produce food and energy in a sustainable way for humans and their children. Inside, readers will find articles that explore climate change, increasing food and fuel prices, poor-nation starvation, rich-nation obesity, water pollution, soil erosion, fertility loss, pest control and biodiversity depletion. Instead of solving problems using the classical painkiller approach, which seeks to limit negative impacts, sustainable agriculture treats challenges at their source. Because most societal issues are in fact intertwined, global, and fast-developing, sustainable agriculture will bring solutions that have the potential to build a more peaceful world. This book will help scientists, decision-makers, professors, farmers and politicians build safer agriculture, energy and food systems for future generations.
Trace Determination of Pesticides and their Degradation Products in Water (BOOK REPRINT)
Author: Damia Barcelo
Publisher: Elsevier
ISBN: 008054312X
Category : Science
Languages : en
Pages : 557
Book Description
Trace Determination of Pesticides and their Degradation Products in Water is a critical compilation of analytical methods for the monitoring of pesticides and their degradation products in water. It contains up-to-date material and is the result of the authors' experience in the pesticide analysis field. The book is structured in six chapters, starting from general aspects of pesticides like usage, physicochemical parameters and occurrence in the environment. A second chapter is devoted to sampling from water matrices, stability methods of pesticides in water and quality assurance issues. The general chromatographic methods for pesticides are reported, including the newly developed electrophoresis methods and GC-MS and LC-MS confirmatory analytical methods. Sample preparation methodologies, including off-line and on-line techniques are described in the next two chapters, with a comprehensive list of examples of pesticides and many metabolites, including the use of different GC-methods and LC-methods. The final chapter is devoted to the development of biological techniques, immunoassays and biosensors, for the trace determination of pesticides in water samples.
Publisher: Elsevier
ISBN: 008054312X
Category : Science
Languages : en
Pages : 557
Book Description
Trace Determination of Pesticides and their Degradation Products in Water is a critical compilation of analytical methods for the monitoring of pesticides and their degradation products in water. It contains up-to-date material and is the result of the authors' experience in the pesticide analysis field. The book is structured in six chapters, starting from general aspects of pesticides like usage, physicochemical parameters and occurrence in the environment. A second chapter is devoted to sampling from water matrices, stability methods of pesticides in water and quality assurance issues. The general chromatographic methods for pesticides are reported, including the newly developed electrophoresis methods and GC-MS and LC-MS confirmatory analytical methods. Sample preparation methodologies, including off-line and on-line techniques are described in the next two chapters, with a comprehensive list of examples of pesticides and many metabolites, including the use of different GC-methods and LC-methods. The final chapter is devoted to the development of biological techniques, immunoassays and biosensors, for the trace determination of pesticides in water samples.
The Monsanto Papers
Author: Carey Gillam
Publisher: Island Press
ISBN: 1642830569
Category : Social Science
Languages : en
Pages : 354
Book Description
Lee Johnson was a man with simple dreams. All he wanted was a steady job and a nice home for his wife and children, something better than the hard life he knew growing up. He never imagined that he would become the face of a David-and-Goliath showdown against one of the world’s most powerful corporate giants. But a workplace accident left Lee doused in a toxic chemical and facing a deadly cancer that turned his life upside down. In 2018, the world watched as Lee was thrust to the forefront of one the most dramatic legal battles in recent history. The Monsanto Papers is the inside story of Lee Johnson’s landmark lawsuit against Monsanto. For Lee, the case was a race against the clock, with doctors predicting he wouldn’t survive long enough to take the witness stand. For the eclectic band of young, ambitious lawyers representing him, it was a matter of professional pride and personal risk, with millions of dollars and hard-earned reputations on the line. For the public at large, the lawsuit presented a question of corporate accountability. With enough money and influence, could a company endanger its customers, hide evidence, manipulate regulators, and get away with it all—for decades? Readers will be astounded by the depth of corruption uncovered, captivated by the shocking twists, and moved by Lee’s quiet determination to see justice served. With gripping narrative force that reads like fiction, The Monsanto Papers takes readers behind the scenes of a grueling legal battle, pulling back the curtain on the frailties of the American court system and the lengths to which lawyers will go to fight corporate wrongdoing.
Publisher: Island Press
ISBN: 1642830569
Category : Social Science
Languages : en
Pages : 354
Book Description
Lee Johnson was a man with simple dreams. All he wanted was a steady job and a nice home for his wife and children, something better than the hard life he knew growing up. He never imagined that he would become the face of a David-and-Goliath showdown against one of the world’s most powerful corporate giants. But a workplace accident left Lee doused in a toxic chemical and facing a deadly cancer that turned his life upside down. In 2018, the world watched as Lee was thrust to the forefront of one the most dramatic legal battles in recent history. The Monsanto Papers is the inside story of Lee Johnson’s landmark lawsuit against Monsanto. For Lee, the case was a race against the clock, with doctors predicting he wouldn’t survive long enough to take the witness stand. For the eclectic band of young, ambitious lawyers representing him, it was a matter of professional pride and personal risk, with millions of dollars and hard-earned reputations on the line. For the public at large, the lawsuit presented a question of corporate accountability. With enough money and influence, could a company endanger its customers, hide evidence, manipulate regulators, and get away with it all—for decades? Readers will be astounded by the depth of corruption uncovered, captivated by the shocking twists, and moved by Lee’s quiet determination to see justice served. With gripping narrative force that reads like fiction, The Monsanto Papers takes readers behind the scenes of a grueling legal battle, pulling back the curtain on the frailties of the American court system and the lengths to which lawyers will go to fight corporate wrongdoing.
The Shikimate Pathway
Author: Edwin Haslam
Publisher: Elsevier
ISBN: 1483161188
Category : Science
Languages : en
Pages : 327
Book Description
The Shikimate Pathway gives a bird's eye view of the shikimate pathway and its implications for the life of a range of organisms. Topics covered in this book include the chemistry of intermediates in the shikimate pathway; biosynthesis of aromatic amino acids in this pathway; its metabolites; and its role in higher plants. This book is comprised of six chapters and begins by introducing the reader to shikimic acid, a natural product derived from the plant Illicium religiosum, along with the mechanistic and stereochemical aspects of the reactions of the shikimate pathway. The biosynthesis of aromatic amino acids from chorismate is also described, and then the discussion turns to the chemical properties and the detailed stereochemistry of intermediates and enzymes in the shikimate pathway. The next chapter examines the biosynthesis of isoprenoid quinones involved in electron transport and the folic acid group of co-enzymes in the shikimate pathway. The metabolism of the aromatic amino acids in microorganisms and higher organisms is considered, along with the biosynthesis and physiological functions of phenylpropanoid compounds and their derivatives in the shikimate pathway in higher plants. This book will be of general value to practitioners in the many and varied areas of biochemical research associated with metabolism.
Publisher: Elsevier
ISBN: 1483161188
Category : Science
Languages : en
Pages : 327
Book Description
The Shikimate Pathway gives a bird's eye view of the shikimate pathway and its implications for the life of a range of organisms. Topics covered in this book include the chemistry of intermediates in the shikimate pathway; biosynthesis of aromatic amino acids in this pathway; its metabolites; and its role in higher plants. This book is comprised of six chapters and begins by introducing the reader to shikimic acid, a natural product derived from the plant Illicium religiosum, along with the mechanistic and stereochemical aspects of the reactions of the shikimate pathway. The biosynthesis of aromatic amino acids from chorismate is also described, and then the discussion turns to the chemical properties and the detailed stereochemistry of intermediates and enzymes in the shikimate pathway. The next chapter examines the biosynthesis of isoprenoid quinones involved in electron transport and the folic acid group of co-enzymes in the shikimate pathway. The metabolism of the aromatic amino acids in microorganisms and higher organisms is considered, along with the biosynthesis and physiological functions of phenylpropanoid compounds and their derivatives in the shikimate pathway in higher plants. This book will be of general value to practitioners in the many and varied areas of biochemical research associated with metabolism.
Glyphosate: Chemistry, Uses and Safety Concerns
Author: Ron Quinn
Publisher:
ISBN: 9781536140026
Category : Glyphosate
Languages : en
Pages : 0
Book Description
Chemical herbicides are widely used in food production throughout the world. At the present time, they represent approximately 40% of chemical products sales, followed by insecticides, fungicides, and other types of pesticides. Among these products, commercial formulations based on N-phosphonomethyl-glycine (PMG), commonly known as glyphosate, are the most used worldwide. Such herbicidal formulations play a key role in promoting crop yields. In Glyphosate: Chemistry, Uses and Safety Concerns review information on the presence of glyphosate-based herbicides in the environment, their potentially harmful effects, their influence on soil microbial communities and their capacity to adsorb to clay particles (which affects their environmental availability).The objective of the following work was to investigate the best way to achieve slow release of glyphosate using layered double hydroxides (LDHs) to minimize the environmental impacts of this herbicide. LDHs are also called anionic clays because they can host negatively charged species between their layers. They are best stabilized by anions with high charge density, such as carbonate. Understanding the release dynamics of glyphosate in homogeneous solutions of anions that are commonly found in the soil is important, since many crops require prior soil correction, altering the pH and also the availability of anions.In one study, the chelating capacity, coordination modes and structural chemistry of glyphosate with Ni (II) cations were investigated in solution and in the solid state. Glyphosate was purified from commercial Roundup WG (Monsanto), and characterized by 31P NMR, FTIR and melting point. The nickel complexes were prepared from Ni(NO3)2 solutions at pH = 8.0 and 4.0, and characterized by solid-state infrared spectroscopy (4000-150 cm-1) and elemental analysis (CHN). The solids were also studied by thermal analysis and X-ray absorption spectroscopy (XAS) using synchrotron radiation (LNLS, Brazil).Studies show that glyphosate has an oral absorption of 20 to 40% and is considered to be of low toxicity to mammals; however, recent research has shown that it can induce serious damage to mammalian cells. The authors examine suggested mechanisms of toxicity, including the blocking of mitochondrial oxidative phosphorylation, inhibition of cytochrome p450 activity, inhibition of intestinal arylhydrocarbohydroxylase activity, changes in glucose 6-phosphate dehydrogenase activity, DNA damage, hormonal changes, channel openings of calcium, and neurotoxicity involving NMDA receptor activation.The widespread and frequent use of glyphosate has increased concern about potential adverse effects on human health. Due to more stringent legislation on wastewater discharge and purity of drinking water, the authors discuss the development of an effective remediation technology for the decontamination of glyphosate. Although glyphosate residues can efficiently be removed by advanced technologies, the treatments are usually expensive and difficult to maintain. Therefore, different methods and options should be considered.
Publisher:
ISBN: 9781536140026
Category : Glyphosate
Languages : en
Pages : 0
Book Description
Chemical herbicides are widely used in food production throughout the world. At the present time, they represent approximately 40% of chemical products sales, followed by insecticides, fungicides, and other types of pesticides. Among these products, commercial formulations based on N-phosphonomethyl-glycine (PMG), commonly known as glyphosate, are the most used worldwide. Such herbicidal formulations play a key role in promoting crop yields. In Glyphosate: Chemistry, Uses and Safety Concerns review information on the presence of glyphosate-based herbicides in the environment, their potentially harmful effects, their influence on soil microbial communities and their capacity to adsorb to clay particles (which affects their environmental availability).The objective of the following work was to investigate the best way to achieve slow release of glyphosate using layered double hydroxides (LDHs) to minimize the environmental impacts of this herbicide. LDHs are also called anionic clays because they can host negatively charged species between their layers. They are best stabilized by anions with high charge density, such as carbonate. Understanding the release dynamics of glyphosate in homogeneous solutions of anions that are commonly found in the soil is important, since many crops require prior soil correction, altering the pH and also the availability of anions.In one study, the chelating capacity, coordination modes and structural chemistry of glyphosate with Ni (II) cations were investigated in solution and in the solid state. Glyphosate was purified from commercial Roundup WG (Monsanto), and characterized by 31P NMR, FTIR and melting point. The nickel complexes were prepared from Ni(NO3)2 solutions at pH = 8.0 and 4.0, and characterized by solid-state infrared spectroscopy (4000-150 cm-1) and elemental analysis (CHN). The solids were also studied by thermal analysis and X-ray absorption spectroscopy (XAS) using synchrotron radiation (LNLS, Brazil).Studies show that glyphosate has an oral absorption of 20 to 40% and is considered to be of low toxicity to mammals; however, recent research has shown that it can induce serious damage to mammalian cells. The authors examine suggested mechanisms of toxicity, including the blocking of mitochondrial oxidative phosphorylation, inhibition of cytochrome p450 activity, inhibition of intestinal arylhydrocarbohydroxylase activity, changes in glucose 6-phosphate dehydrogenase activity, DNA damage, hormonal changes, channel openings of calcium, and neurotoxicity involving NMDA receptor activation.The widespread and frequent use of glyphosate has increased concern about potential adverse effects on human health. Due to more stringent legislation on wastewater discharge and purity of drinking water, the authors discuss the development of an effective remediation technology for the decontamination of glyphosate. Although glyphosate residues can efficiently be removed by advanced technologies, the treatments are usually expensive and difficult to maintain. Therefore, different methods and options should be considered.
The plant microbiome and its importance for plant and human health
Author: Martin Grube
Publisher: Frontiers E-books
ISBN: 2889193780
Category : Botany
Languages : en
Pages : 190
Book Description
The study of plant-microbe associations by new techniques has significantly improved our understanding of the structure and specificity of the plant microbiome. Yet, microbiome function and the importance of the plant’s microbiome in the context of human and plant health are largely unexplored. Comparable with our human microbiome, millions of microbes inhabit plants, forming complex ecological communities that influence plant growth and health through its collective metabolic activities and host interactions. Viewing the microbiota from an ecological perspective can provide insight into how to promote plant health and stress tolerance of their hosts or how to adapt to a changing climate by targeting this microbial community. Moreover, the plant microbiome has a substantial impact on human health by influencing our gut microbiome by eating raw plants such as lettuce and herbs but also by influencing the microbiome of our environment through airflow. This research topic comprising reviews, original and opinion articles highlights the current knowledge regarding plant microbiomes, their specificity, diversity and function as well as all aspects studying the management of plant microbiomes to enhance plant growth, health quality and stress tolerance.
Publisher: Frontiers E-books
ISBN: 2889193780
Category : Botany
Languages : en
Pages : 190
Book Description
The study of plant-microbe associations by new techniques has significantly improved our understanding of the structure and specificity of the plant microbiome. Yet, microbiome function and the importance of the plant’s microbiome in the context of human and plant health are largely unexplored. Comparable with our human microbiome, millions of microbes inhabit plants, forming complex ecological communities that influence plant growth and health through its collective metabolic activities and host interactions. Viewing the microbiota from an ecological perspective can provide insight into how to promote plant health and stress tolerance of their hosts or how to adapt to a changing climate by targeting this microbial community. Moreover, the plant microbiome has a substantial impact on human health by influencing our gut microbiome by eating raw plants such as lettuce and herbs but also by influencing the microbiome of our environment through airflow. This research topic comprising reviews, original and opinion articles highlights the current knowledge regarding plant microbiomes, their specificity, diversity and function as well as all aspects studying the management of plant microbiomes to enhance plant growth, health quality and stress tolerance.