Author: Alfred Pischinger
Publisher: North Atlantic Books
ISBN: 1556436882
Category : Science
Languages : en
Pages : 233
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Book Description
The workings of the suitable environment for cells—called the extracellular matrix (ECM) and ground regulation—has occupied the European medical tradition since the early part of the 20th century. As it has become more clear that the origin of disease and its first signals register in the connective tissue, or myofascia, cellular pathologists and biochemists have sought to circumscribe networks of cell communication and microcirculation in the ECM. Alfred Pischinger (1899-1982) continued this line of work by further studying, in work published from 1926 through the late seventies, the connections of the ECM to the hormonal and autonomic systems. In the last twenty years Professor and Doctor of Natural Sciences Hartmut Heine and his colleagues have carried on Pischinger’s work, here summarized in one volume. Part One encompasses theoretical underpinnings; Parts Two and Three address applications and directions for further research. This updated English-language translation not only is an account of the work of Pischinger’s successors—Heine, Otto Bergsmann, and Felix Perger, (the three editors of this volume) and their many colleagues—but notes the positive development of complementary therapies based on this understanding of histology. Acupuncture is referenced directly. Both in Europe and the States the work of manual therapists, including Rolfers, cranio- sacral therapists, and other somatic disciplines have been informed for many years by Pischinger’s outsider model of how changes in the EMC register in the central nervous system and the brain, and are conveyed back to the periphery and connected organs. Heine’s exciting recent work shows that the regulation and construction of the ECM have relationships to cybernetic non-linear systems and phase transitions.
Author: Robert Mecham
Publisher: Springer Science & Business Media
ISBN: 3642165559
Category : Science
Languages : en
Pages : 429
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Book Description
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Author: Alta Smit
Publisher: Thieme
ISBN: 3131469714
Category : Medical
Languages : en
Pages : 182
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Book Description
Written by international experts in the field, this book provides a comprehensive introduction to the fundamental principles and clinical practice of bioregulatory medicine. It opens with an overview of core concepts in homotoxicology, including the human body's defense and regulation systems, followed by a chapter on the development and evolution of illness. The authors cover the different preparation groups and discuss in detail the basic principles of antihomotoxic therapy: drainage and detoxification, immunomodulation, and cell and organ support. The final chapter focuses on the practical aspects of bioregulatory treatment, including the selection and availability of medications, indications, contraindications, and therapeutic strategies for a variety of common diseases.Highlights: Insights from renowned experts in homotoxicology Poster-size version of the Disease Evolution Table (DET), a key tool in daily practice Plant-, mineral-, and organ-based medications--how they work Practical information on various treatment methods, such as ointment dressings, injection therapies, and biopuncture 80 high-quality illustrations and diagrams that demonstrate key concepts Introduction to Bioregulatory Medicine is a valuable textbook for medical students, medical doctors, naturopathic physicians, homeopaths, and other health care professionals who wish to expand their knowledge in this field.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Matthew Wood
Publisher: Simon and Schuster
ISBN: 1644112957
Category : Health & Fitness
Languages : en
Pages : 315
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Book Description
• Examines the function of the extracellular matrix, the inner ocean that unifies all our cells and controls them in a coordinated and integrated fashion • Explores how the extracellular matrix builds and repairs itself and how holistic therapy can be applied based on this knowledge • Introduces new and old holistic and herbal protocols for treatment of the matrix The cells in our bodies are not independent units. They do not control their own feeding, elimination, migration, or reproduction; they are controlled by signals from the extracellular matrix (ECM) that surrounds them. This all-encompassing inner ocean unifies all our cells and controls them in a coordinated and integrated fashion. Revealing the stunning implications of the extracellular matrix, Matthew Wood shows how it clearly explains the actions and efficacy of holistic therapies. He explores the groundbreaking research of Alfred Pischinger, who discovered the ECM in 1975, as well as the role of the matrix in transmitting and enacting the genetic code, including the roles of the mitochondria, the nucleus, and ribosomes. Wood explains how modern drugs, directed at specific receptors on the cell membrane, interfere with bodily self-regulation. He details how holistic therapies modify the environment of the cell and strengthen the whole, bringing the body back to homeostasis and consequently offering true healing.
Author: J. Gordon Betts
Publisher:
ISBN: 9781947172807
Category :
Languages : en
Pages : 0
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Book Description
Author: Fred W. Keeley
Publisher: Springer Science & Business Media
ISBN: 3642360025
Category : Science
Languages : en
Pages : 297
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Book Description
The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.
Author: Don Ross
Publisher: MIT Press
ISBN: 0262681684
Category : Psychology
Languages : en
Pages : 455
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Book Description
In this study, Don Ross explores the relationship of economics to other branches of behavioral science, asking, in the course of his analysis, under what interpretation economics is a sound empirical science. The book explores the relationships between economic theory and the theoretical foundations of related disciplines that are relevant to the day-to-day work of economics—the cognitive and behavioral sciences. It asks whether the increasingly sophisticated techniques of microeconomic analysis have revealed any deep empirical regularities—whether technical improvement represents improvement in any other sense. Casting Daniel Dennett and Kenneth Binmore as its intellectual heroes, the book proposes a comprehensive model of economic theory that, Ross argues, does not supplant, but recovers the core neoclassical insights, and counters the caricaturish conception of neoclassicism so derided by advocates of behavioral or evolutionary economics. Because he approaches his topic from the viewpoint of the philosophy of science, Ross devotes one chapter to the philosophical theory and terminology on which his argument depends and another to related philosophical issues. Two chapters provide the theoretical background in economics, one covering developments in neoclassical microeconomics and the other treating behavioral and experimental economics and evolutionary game theory. The three chapters at the heart of the argument then apply theses from the philosophy of cognitive science to foundational problems for economic theory. In these chapters, economists will find a genuinely new way of thinking about the implications of cognitive science for economics, and cognitive scientists will find in economic behavior, a new testing site for the explanations of cognitive science.
Author: Tiago G. Fernandes
Publisher: Elsevier
ISBN: 1908818301
Category : Science
Languages : en
Pages : 236
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Book Description
Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. - Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches - Envisages the use of stem cells in regenerative medicine and drug screening applications - Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies
Author: Herbert F. Wang
Publisher: Princeton University Press
ISBN: 140088568X
Category : Science
Languages : en
Pages : 301
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Book Description
The theory of linear poroelasticity describes the interaction between mechanical effects and adding or removing fluid from rock. It is critical to the study of such geological phenomena as earthquakes and landslides and is important for numerous engineering projects, including dams, groundwater withdrawal, and petroleum extraction. Now an advanced text synthesizes in one place, with one notation, numerous classical solutions and applications of this highly useful theory. The introductory chapter recounts parallel developments in geomechanics, hydrogeology, and reservoir engineering that are unified by the tenets of poroelasticity. Next, the theory's constitutive and governing equations and their associated material parameters are described. These equations are then specialized for different simplifying geometries: unbounded problem domains, uniaxial strain, plane strain, radial symmetry, and axisymmetry. Example problems from geomechanics, hydrogeology, and petroleum engineering are incorporated throughout to illustrate poroelastic behavior and solution methods for a wide variety of real-world scenarios. The final chapter provides outlines for finite-element and boundary-element formulations of the field's governing equations. Whether read as a course of study or consulted as a reference by researchers and professionals, this volume's user-friendly presentation makes accessible one of geophysics' most important subjects and will do much to reduce poroelasticity's reputation as difficult to master.
