The Epidemiology and Control of Human African Trypanosomiasis in Uganda

The Epidemiology and Control of Human African Trypanosomiasis in Uganda PDF Author: Christine Amongi Acup
Publisher:
ISBN:
Category :
Languages : en
Pages : 0

Get Book Here

Book Description


Epidemiology and Control of Human African Trypanosomiasis in Uganda

Epidemiology and Control of Human African Trypanosomiasis in Uganda PDF Author: Christine Amongi Acup
Publisher:
ISBN:
Category :
Languages : en
Pages :

Get Book Here

Book Description


Control and Surveillance of Human African Trypanosomiasis

Control and Surveillance of Human African Trypanosomiasis PDF Author:
Publisher: World Health Organization
ISBN: 9241209844
Category : Medical
Languages : en
Pages : 249

Get Book Here

Book Description
This report provides information about new diagnostic approaches, new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease. Human African Tryponosomiasis (HAT) is a disease that afflicts populations in rural Africa, where the tsetse fly vector that transmits the causative trypanosome parasites thrives. There are two forms of HAT: one, known as gambiense HAT, is endemic in West and Central Africa and causes over 95% of current cases; the other, known as rhodesiense HAT, is endemic in East and southern Africa and accounts for the remainder of cases. The presence of parasites in the brain leads to progressive neurological breakdown. Changes to sleep-wake patterns are among the symptoms that characterize the disease, also known as "sleeping sickness". Eventually, patients fall into a coma and die if not treated. Different treatments are available against parasites present in the haemolymphatic system (first stage) and those that have entered the brain (second stage). Currently, lumbar puncture is required to select the appropriate drug.

Epidemiology and Control of African Trypanosomiasis

Epidemiology and Control of African Trypanosomiasis PDF Author: WHO Expert Committee on the Epidemiology and Control of African Trypanosomiasis
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 132

Get Book Here

Book Description


African Sleeping Sickness

African Sleeping Sickness PDF Author: Jonathan Musere
Publisher: Edwin Mellen Press
ISBN: 9780889462809
Category : Medical
Languages : en
Pages : 208

Get Book Here

Book Description
Based on an interplay of bio-ecology, medicine, anthropology, history, and sociopolitics, this work compares and contrasts the role of communalist traditional, colonial, and postcolonial agencies in the control or eruption of trypanosomiasis (sleeping sickness) in man and cattle in Uganda.

One Health, 2nd Edition

One Health, 2nd Edition PDF Author: Jakob Zinsstag
Publisher: CABI
ISBN: 1789242576
Category : Medical
Languages : en
Pages : 459

Get Book Here

Book Description
One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.

Control and Surveillance of Human African Trypanosomiasis

Control and Surveillance of Human African Trypanosomiasis PDF Author: World Health Organization
Publisher:
ISBN: 9789240691728
Category : African trypanosomiasis
Languages : en
Pages : 237

Get Book Here

Book Description
This report provides information about new diagnostic approaches new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping. The roles of human and animal reservoirs and the tsetse fly vectors that transmit the parasites are emphasized. The new information has formed the basis for an integrated strategy with which it is hoped that elimination of HAT will be achieved. The report also contains recommendations on the approaches that will lead to elimination of the disease.Human African Tryponosomiasis (HAT) is a disease that afflicts populations in rural Africa where the tsetse fly vector that transmits the causative trypanosome parasites thrives. There are two forms of HAT: one known as gambiense HAT is endemic in West and Central Africa and causes over 95% of current cases; the other known as rhodesiense HAT is endemic in East and southern Africa and accounts for the remainder of cases. The presence of parasites in the brain leads to progressive neurological breakdown. Changes to sleep-wake patterns are among the symptoms that characterize the disease also known as sleeping sickness . Eventually patients fall into a coma and die if not treated. Different treatments are available against parasites present in the haemolymphatic system (first stage) and those that have entered the brain (second stage). Currently lumbar puncture is required to select the appropriate drug.

The Trypanosomiases

The Trypanosomiases PDF Author: Ian Maudlin
Publisher: CABI
ISBN: 9780851990347
Category : Medical
Languages : en
Pages : 644

Get Book Here

Book Description
This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.

WHO Interim Guidelines for the Treatment of Gambiense Human African Trypanosomiasis

WHO Interim Guidelines for the Treatment of Gambiense Human African Trypanosomiasis PDF Author: World Health Organization
Publisher:
ISBN:
Category :
Languages : en
Pages : 44

Get Book Here

Book Description
Human African trypanosomiasis (HAT), or sleeping sickness, is a parasitic infection that is almost invariably fatal unless treated. It is a neglected tropical disease that occurs in sub-Saharan Africa. The incidence of the disease is declining in response to intensive surveillance and control in endemic areas. As a result, HAT is among the neglected tropical diseases targeted by the World Health Organization (WHO) for elimination. WHO maintains exhaustive records of all declared cases; in 2018, a historically low number of cases (less than 1000) was reported. The remarkable progress in the control of gambiense HAT has relied on case-finding and curative treatment, a strategy that interrupts transmission by depleting the reservoir of parasites in humans. This has been combined occasionally with vector control activities. The subject of these guidelines, therefore, is of utmost importance for the continuation of progress to eliminate HAT. The recent approval of a new medicine (fexinidazole) for the treatment of gambiense HAT has opened new possibilities for the management of cases and thus warrants the new WHO recommendations contained herein. While studies of fexinidazole and other therapies are ongoing, these guidelines are considered interim guidelines until new information becomes available. This document focuses on the management of patients affected by gambiense HAT and constitutes an update to the WHO therapeutic guidance issued in 2013.

Tsetse Biology and Ecology

Tsetse Biology and Ecology PDF Author: Stephen G. A. Leak
Publisher: ILRI (aka ILCA and ILRAD)
ISBN: 9780851993003
Category : Medical
Languages : en
Pages : 598

Get Book Here

Book Description
Domestic livestock in Africa are of importance not only as a source of milk and meat but also as a source of animal traction enabling farmers to cultivate larger areas, with crops providing the staple foods. Trypanosomosis, a parasitic disease transmitted cyclically by the tsetse fly (Glossina spp.), is arguably still the main constraint to livestock production on the continent, preventing full use of the land to feed the rapidly increasing human population. Sleeping sickness, the disease caused in humans by species of Trypanosoma, is an important and neglected disease posing a threat to millions of people in tsetse-infested areas. Often wrongly thought of as a disease of the past, the prevalence of human sleeping sickness is increasing in many areas. Although alternative methods to control the disease are being investigated, such as immunological approaches, use of chemotherapy or exploitation of the trypanotolerance trait, it is only control or eradication of the tsetse fly vector which will remove the threat of the disease rather than providing a better means of "living" with it. As a result of the economic impact of tsetse-transmitted Trypanosomosis, a large amount of research literature has been produced. This book provides a comprehensive review of this literature. The text is divided into four parts: tsetse biology and ecology, epidemiology, vector control and control of trypanosomosis. The book is invaluable for medical and veterinary entomologists, parasitologists and epidemiologists.