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Author: Stuart Warren
Publisher: Stuart Warren
ISBN: 9781637608296
Category :
Languages : en
Pages : 390
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Book Description
Eight hundred years after humanity's extinction, Aia, an android, awakens in the tundra of Alberta, Canada. It has no knowledge of the time before, and the world ahead holds the answers it seeks. What happened to its creator? Will it find its place in machine society? As Aia encounters civilization, it quickly learns that self-actualization is not for all: machines live within a caste system, bound to their peers with no means of promotion. Within the eclectic city-state of HUB 9, situated in the idyllic ruins of San Francisco, Aia is indentured to a sewage processing facility and nearly gives up hope until it is mysteriously promoted from its current assignment by Donnie Eberstark, a member of the social elite bent on preserving humanity's legacy and culture. While discovering where it fits in, Aia becomes embroiled in a high stakes political movement that will decide the future of machine-kind. Immersive, meditative, and witty, Stuart Warren's second full-length novel Dynamic Synapse Protocol explores the aftermath of humanity's fall and the difficult choice between exalting the past or embracing the future.
Author: Stuart Warren
Publisher: Stuart Warren
ISBN: 9781637608296
Category :
Languages : en
Pages : 390
Get Book Here
Book Description
Eight hundred years after humanity's extinction, Aia, an android, awakens in the tundra of Alberta, Canada. It has no knowledge of the time before, and the world ahead holds the answers it seeks. What happened to its creator? Will it find its place in machine society? As Aia encounters civilization, it quickly learns that self-actualization is not for all: machines live within a caste system, bound to their peers with no means of promotion. Within the eclectic city-state of HUB 9, situated in the idyllic ruins of San Francisco, Aia is indentured to a sewage processing facility and nearly gives up hope until it is mysteriously promoted from its current assignment by Donnie Eberstark, a member of the social elite bent on preserving humanity's legacy and culture. While discovering where it fits in, Aia becomes embroiled in a high stakes political movement that will decide the future of machine-kind. Immersive, meditative, and witty, Stuart Warren's second full-length novel Dynamic Synapse Protocol explores the aftermath of humanity's fall and the difficult choice between exalting the past or embracing the future.
Author: John Smythies
Publisher: MIT Press
ISBN: 9780262264679
Category : Medical
Languages : en
Pages : 174
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Book Description
A comprehensive review of current research on synaptic plasticity. The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease.
Author: Wulfram Gerstner
Publisher: Cambridge University Press
ISBN: 1107060834
Category : Computers
Languages : en
Pages : 591
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Book Description
This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.
Author: Yoshiaki Toyama
Publisher: Springer Nature
ISBN: 9811379084
Category : Medical
Languages : en
Pages : 285
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Book Description
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Author: Max R. Bennett
Publisher: CRC Press
ISBN: 0203302540
Category : Science
Languages : en
Pages : 351
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Book Description
The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.
Author: A.C. Damask
Publisher: Elsevier
ISBN: 0323154646
Category : Medical
Languages : en
Pages : 352
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Book Description
Synapse, Neuron, Brain, the third and last volume in the series Medical Physics, focuses on neurons and their interactions. Comprised of seven chapters regarding the brain's synapses and nerves, this volume concludes through the presentation of medical physics and its applications. An introductory chapter of this volume provides the necessary basic concepts and theories needed in the understanding of the book. This is followed by a discussion on the brain and its interconnections with the spinal cord. Chapter 3 focuses on the importance of evoked potentials as a diagnostic tool for the sensory organ and the neural processing of the stimuli. Chemical and electrical properties of synapses are also given emphasis. Other topics covered in this volume include the rall theory and neuronal integration; membrane noise at synaptic junctions; and new techniques on brain studies (autoradiography, positron annihilation, and nuclear magnetic resonance). As with the other volumes, this also caters to persons in various disciplines such as medicine, physiology, physics, and biology.
Author: Stephen D. Meriney
Publisher: Academic Press
ISBN: 0128153210
Category : Medical
Languages : en
Pages : 530
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Book Description
Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winning researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders. - Provides a comprehensive reference on synaptic structure, physiology, function and neurotransmission - Discusses many landmark experiments in the field of synaptic transmission to emphasize core principles - Includes references to primary scientific literature, relevant review articles and books, many of which could be assigned as discussion material for courses focused on this topic
Author: Rodolfo Riascos Llinás
Publisher:
ISBN: 9780195116526
Category : Medical
Languages : en
Pages : 234
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Book Description
The squid giant synapse is the single most important model for investigating the transmitter release mechanism in chemical junctions. This unique book, by a leading expert in the field, gives a concise overview of all that has been learned about synaptic transmission in this superb model system. It covers in detail the biophysics of the voltage-dependent calcium currents, calcium concentration microdomains, and much of the molecular basis for the triggering of the secretory event. Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission. One program is a modeling tool designed for working neuroscientists, and the other teaches the basic principles of synaptic transmission by allowing students to alter the parameters, essentially without limits, and see the effects on the action potential over time. Anyone studying this central topic of neuroscience will find this book an invaluable resource.
Author: Cosima T. Baldari
Publisher: Humana
ISBN: 9781071631379
Category : Science
Languages : en
Pages : 0
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Book Description
This new collection features the most up-to-date essential protocols that are currently being used to study the immune synapse. Beginning with methods for making biophysical measurements, the volume continues by covering the cell biology of synapses, methods for advanced substrate engineering, mechanobiology topics, new technologies to describe and manipulate synaptic components, as well as methods related to sites of action and immunotherapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, The Immune Synapse: Methods and Protocols, Second Edition serves as an ideal practical guide for researchers working in this dynamic field. Chapters 5, 11,18, 27, 30, and 32 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author: Theodore W. Berger
Publisher: MIT Press
ISBN: 9780262025775
Category : Medical
Languages : en
Pages : 428
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Book Description
The latest advances in research on intracranial implantation of hardware models of neural circuitry.
