Author: Guillermo Terzano
Publisher:
ISBN:
Category :
Languages : en
Pages : 6

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Book Description

Author: World Health Organization. Regional Office for Europe
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 52

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Book Description

Author: United States. Veterans Administration
Publisher:
ISBN:
Category : Cytodiagnosis
Languages : en
Pages : 108

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Book Description

Author: Hywel Williams
Publisher: John Wiley & Sons
ISBN: 9781444300178
Category : Medical
Languages : en
Pages : 740

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Book Description
Evidence-based Dermatology, Second Edition is aunique book in the field of clinical dermatology. Written andedited by some of the world’s leading experts inevidence-based dermatology, it takes a highly evidence-basedapproach to the treatment of all major and many of the less commonskin conditions. The toolbox at the beginning of the book explaining how tocritically appraise different studies, along with the comprehensivereviewing and appraisal of evidence in the clinical chapters makesthis book distinctive in its field as do the treatmentrecommendations which are based on the discussion of the bestavailable evidence using a question-driven approach and a commonstructure on dealing with efficacy, drawbacks and implications forclinical practice.

Author: Pranab Dey
Publisher: JP Medical Ltd
ISBN: 9386261898
Category : Medical
Languages : en
Pages : 381

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Book Description
Exfoliative cytology, which is a quick and simple procedure, is an important alternative to biopsy in certain situations. In exfoliative cytology, cells shed from body surfaces, such as the inside of the mouth, are collected and examined. This technique is useful only for the examination of surface cells and often requires additional cytological analysis to confirm the results (Encyclopaedia Britannica). This book is a comprehensive guide to exfoliative cytopathology presenting 215 real cases supplemented with clinical details and microphotographs. Each case covers a description of the problem, diagnostic criteria and features, differential diagnosis and immunocytochemistry, and treatment options. Divided into eight sections, the book presents cases highlighting cytology in different systems of the body – general, cervical, effusion, respiratory, gastrointestinal tract, urine, cerebrospinal fluid, concluding with a chapter on miscellaneous topics. Cases are presented in multiple choice question format, with detailed answers and suggestions for further reading. Key Points Comprehensive guide to exfoliative cytology Presents 215 real cases supplemented with clinical details and microphotographs Covers cytology of different systems of the body Cases presented in multiple choice question format

Author: American Cancer Society
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 88

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Book Description

Author: Arjun Singh
Publisher: LAP Lambert Academic Publishing
ISBN: 9783843375283
Category : Cytology
Languages : en
Pages : 96

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Book Description
Oral cancer is a major problem in India and accounts for 50% -70% of all cancers diagnosed as compared to 2-3% in UK and USA, it is due to certain personal habits of our population, like tobacco chewing and smoking. Oral exfoliative cytology seems to offer a good method of screening of the population with suspicious lesions of oral premalignant and malignant conditions. The oral cytology is simple and out patients department procedure with a high accuracy. It can be useful for surgeons, physician and dentist when one hesitate to perform an invasive procedure, like a biopsy, or desire more information regarding a lesion before referring the patients to the higher center. Oral cytology can also be used for the ancillary testing like molecular study, flow cytometery and immunocytochemistry. This book provides wide knowledge on the procedure and applicability of the oral exfoliative cytology which will be beneficial for Pathologists, General Physicians, Surgeons, and Dentists.

Author: National Cancer Institute (U.S.)
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 134

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Book Description

Author: Alecsandru Ioan Baba
Publisher:
ISBN: 9789732714577
Category : Electronic books
Languages : en
Pages : 787

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Book Description

Author: Shannon Elise Weigum
Publisher:
ISBN:
Category :
Languages : en
Pages : 300

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Book Description
Oral cancer is the sixth most common cancer worldwide and has been marked by high morbidity and poor survival rates that have changed little over the past few decades. Beyond prevention, early detection is the most crucial determinant for successful treatment and survival of cancer. Yet current methodologies for cancer diagnosis based upon pathological examination alone are insufficient for detecting early tumor progression and molecular transformation. Development of new diagnostic tools incorporating tumor biomarkers could enhance early detection by providing molecular-level insight into the biochemical and cellular changes associated with oral carcinogenesis. The work presented in this doctoral dissertation aims to address this clinical need through the development of new automated cellular analysis methods, incorporating lab-on-a-chip sensor techniques, for examination of molecular and morphological biomarkers associated with oral carcinogenesis. Using the epidermal growth factor receptor (EGFR) as a proof-of-principle biomarker, the sensor system demonstrated capacity to support rapid biomarker analysis in less than one-tenth the time of traditional methods and effectively characterized EGFR biomarker over-expression in oral tumor-derived cell lines. Successful extension from in vitro tumor cell lines to clinically relevant exfoliative brush cytology was demonstrated, providing a non-invasive method for sampling abnormal oral epithelium. Incorporation of exfoliative cytology further helped to define the important assay and imaging parameters necessary for dual molecular and morphological analysis in adherent epithelium. Next, this new sensor assay and method was applied in a small pilot study in order to secure an initial understanding of the diagnostic utility of such biosensor systems in clinical settings. Four cellular features were identified as useful indicators of cancerous or pre-cancerous conditions including, the nuclear area and diameter, nuclear-to-cytoplasm ratio, and EGFR biomarker expression. Further examination using linear regression and ROC curve analysis identified the morphological features as the best predictors of disease while a combination of all features may be ideal for classification of OSCC and pre-malignancy with high sensitivity and specificity. Further testing in a larger sample size is necessary to validate this regression model and the LOC sensor technique, but shows strong promise as a new diagnostic tool for early detection of oral cancer.