Author: Zev Jordan Gartner
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 272
Book Description
The Development of DNA-templated Organic Synthesis
Author: Zev Jordan Gartner
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 272
Book Description
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 272
Book Description
The Development of DNA-templated Synthesis for the Creation and Discovery of Synthetic Small Molecules
Author: Rozalina Grubina
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 154
Book Description
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 154
Book Description
Templated Organic Synthesis
Author: François Diederich
Publisher: John Wiley & Sons
ISBN: 3527613536
Category : Science
Languages : en
Pages : 431
Book Description
Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.
Publisher: John Wiley & Sons
ISBN: 3527613536
Category : Science
Languages : en
Pages : 431
Book Description
Template-controlled reactions allow the synthesis of complex molecules which would hardly be achievable through classical methods. This handbook offers authoratative information on how noncovalent and covalent templates can be effectively applied to control reaction rates as well as regio- and stereoselectivity. From the concepts of template control such as molecular imprinting, self-replication, and reversible tether-directed remote functionalization, the reader is led to template-based ring-closing reactions, oligomerizations, and multiple functionalizations and their application in the synthesis of supramolecular scaffolds and natural products. The editors and authors (J. F. Stoddart, G. Wulf, D. Lynn, R. Breslow. F. Diederich, just to name a few ) , all internationally recognized experts in their area, succeeded in presenting the manifold aspects of template-controlled synthesis in a didactic way, making this methodology accessible to a broad readership of organic synthetic chemists. Well-selected, reliable key experimental protocols and an up-to-date reference list underline the practical approach of this valuable handbook. Being the first book of its kind, it will serve as a pacemaker and stimulate future research.
Expanding the Scope of DNA-templated Organic Synthesis and in Vitro Selection
Author: Thomas Marshall Snyder
Publisher:
ISBN: 9780549278948
Category : Biochemical templates
Languages : en
Pages : 278
Book Description
First, we describe a strategy for performing ordered multistep synthesis in a single solution. This system makes use of temperature-sensitive variations in DNA secondary structure to orchestrate an ordered multistep synthesis of a triolefin and a tripeptide in a single solution. This methodology provides a faster, higher-yielding route to multistep DNA-templated products and represents a mode of controlling chemical reactivity that is not accessible in traditional flask-based reaction formats.
Publisher:
ISBN: 9780549278948
Category : Biochemical templates
Languages : en
Pages : 278
Book Description
First, we describe a strategy for performing ordered multistep synthesis in a single solution. This system makes use of temperature-sensitive variations in DNA secondary structure to orchestrate an ordered multistep synthesis of a triolefin and a tripeptide in a single solution. This methodology provides a faster, higher-yielding route to multistep DNA-templated products and represents a mode of controlling chemical reactivity that is not accessible in traditional flask-based reaction formats.
Streitschriften wegen der Ämter und Handwerker 1663 und 1664
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
DNA-templated Synthesis and DNA-encoded Reaction Discovery in Organic Solvents
Author: Mary M. Rozenman
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 280
Book Description
Publisher:
ISBN:
Category : Biochemical templates
Languages : en
Pages : 280
Book Description
A Handbook for DNA-Encoded Chemistry
Author: Robert A. Goodnow, Jr.
Publisher: John Wiley & Sons
ISBN: 1118832671
Category : Science
Languages : en
Pages : 527
Book Description
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available "chemical space" for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Publisher: John Wiley & Sons
ISBN: 1118832671
Category : Science
Languages : en
Pages : 527
Book Description
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available "chemical space" for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Bioconvergence Revolution
Author: Nina Siragusa
Publisher: Springer Nature
ISBN: 303161593X
Category :
Languages : en
Pages : 155
Book Description
Publisher: Springer Nature
ISBN: 303161593X
Category :
Languages : en
Pages : 155
Book Description
A Handbook for DNA-Encoded Chemistry
Author: Robert A. Goodnow, Jr.
Publisher: John Wiley & Sons
ISBN: 1118487680
Category : Science
Languages : en
Pages : 495
Book Description
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
Publisher: John Wiley & Sons
ISBN: 1118487680
Category : Science
Languages : en
Pages : 495
Book Description
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
New Frontiers in Chemical Biology
Author: Mark E. Bunnage
Publisher: Royal Society of Chemistry
ISBN: 184973125X
Category : Medical
Languages : en
Pages : 329
Book Description
This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.
Publisher: Royal Society of Chemistry
ISBN: 184973125X
Category : Medical
Languages : en
Pages : 329
Book Description
This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.