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Author: Karl Leonhard
Publisher: Springer Science & Business Media
ISBN: 3709163714
Category : Medical
Languages : en
Pages : 430
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Book Description
Based on sophisticated clinical descriptions and characteristic symptom patters occurring during the long-term course of psychiatric diseases, Leonhards classification requires that all the clinical features fit for a diagnosis to be made. Always using his own life-long case studies, Leonhard divided the endogenous psychoses into five main nosological groups: on the one hand, the prognostically favourable unipolar affective psychoses, bipolar affective psychoses and cycloid psychoses, and, on the other hand, the prognostically unfavourable unsystematic and systematic schizophrenia. In the meantime, the reliability and validity of this classification have been confirmed by scientific studies and early results provide guidelines for the different origins and varied therapeutic approaches for the specific disease profiles.
Author: Karl Leonhard
Publisher: Springer Science & Business Media
ISBN: 3709163714
Category : Medical
Languages : en
Pages : 430
Get Book
Book Description
Based on sophisticated clinical descriptions and characteristic symptom patters occurring during the long-term course of psychiatric diseases, Leonhards classification requires that all the clinical features fit for a diagnosis to be made. Always using his own life-long case studies, Leonhard divided the endogenous psychoses into five main nosological groups: on the one hand, the prognostically favourable unipolar affective psychoses, bipolar affective psychoses and cycloid psychoses, and, on the other hand, the prognostically unfavourable unsystematic and systematic schizophrenia. In the meantime, the reliability and validity of this classification have been confirmed by scientific studies and early results provide guidelines for the different origins and varied therapeutic approaches for the specific disease profiles.
Author: Karl Leonhard
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3112706951
Category : Medical
Languages : en
Pages : 476
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Book Description
No detailed description available for "The Classification of Endogenous Psychoses".
Author: Karl Leonhard
Publisher:
ISBN: 9783709163726
Category :
Languages : en
Pages : 432
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Book Description
Author: Helmut Beckmann
Publisher: S. Karger AG (Switzerland)
ISBN: 9783805553735
Category : Medical
Languages : en
Pages : 164
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Book Description
Author: Ernst Franzek
Publisher: Springer Science & Business Media
ISBN: 3709163536
Category : Medical
Languages : en
Pages : 156
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Book Description
Contradictory results in schizophrenia research are generally explained as being due to genetic heterogeneity and multiple factor heredity in relationship to manifold environmental factors. The book reports a short overview of all relevant twin studies on schizophrenic psychoses and provides data and case histories on a systematic twin study based on a polydiagnostic approach carried out by two independently working psychiatrists. In addition to the internationally applied operational diagnostic systems of DSM-III-R and ICD 10 Leonhard’s subclassification of schizophrenic psychoses was used. Up to now this sophisticated methodological approach is unique in the world. The data provide strong evidence that the spectrum of psychoses with schizophrenic and schizophrenia-like symptoms is not a continuum of diseases. At least in Leonhard’s three major groups of cycloid psychoses, unsystematic schizophrenias and systematic schizophrenias genetic, somatic and psycho-social factors play a completely different etiological role. Cycloid psychoses and systematic schizophrenias are predominantly caused by "environmental” factors. In unsystematic schizophrenias, however, genetic predisposition is the main etiological factor and environmental factors are subordinate.
Author: Giovanni Stanghellini
Publisher: Oxford University Press
ISBN: 019960925X
Category : Medical
Languages : en
Pages : 345
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Book Description
2013 sees the centenary of Jaspers' foundation of psychopathology as a science with the publication of his magnum opus the Allgemeine Psychopathologie (General Psychopathology), Many of the issues concerning methodology and diagnosis are today the subject of much discussion and debate. This volume brings together leading psychiatrists and philosophers to discuss the impact of this volume, its relevance today, and the legacy it left.
Author: Perminder S. Sachdev
Publisher: Cambridge University Press
ISBN: 1139485229
Category : Medical
Languages : en
Pages :
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Book Description
Schizophrenia may not be a single disease, but the result of a diverse set of related conditions. Modern neuroscience is beginning to reveal some of the genetic and environmental underpinnings of schizophrenia; however, an approach less well travelled is to examine the medical disorders that produce symptoms resembling schizophrenia. This book is the first major attempt to bring together the diseases that produce what has been termed 'secondary schizophrenia'. International experts from diverse backgrounds ask the questions: does this medical disorder, or drug, or condition cause psychosis? If yes, does it resemble schizophrenia? What mechanisms form the basis of this relationship? What implications does this understanding have for aetiology and treatment? The answers are a feast for clinicians and researchers of psychosis and schizophrenia. They mark the next step in trying to meet the most important challenge to modern neuroscience – understanding and conquering this most mysterious of human diseases.
Author: Richard P Bentall
Publisher: Penguin UK
ISBN: 0141909323
Category : Psychology
Languages : en
Pages : 656
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Book Description
Today most of us accept the consensus that madness is a medical condition: an illness, which can be identified, classified and treated with drugs like any other. In this ground breaking and controversial work Richard Bentall shatters the myths that surround madness. He shows there is no reassuring dividing line between mental health and mental illness. Severe mental disorders can no longer be reduced to brain chemistry, but must be understood psychologically, as part of normal behaviour andhuman nature. Bentall argues that we need a radically new way of thinking about psychosis and its treatment. Could it be that it is a fear of madness, rather than the madness itself, that is our problem?
Author: Robert A. McArthur
Publisher: Academic Press
ISBN: 0080920411
Category : Science
Languages : en
Pages : 1367
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Book Description
Animal and Translational Models for CNS Drug Discovery combines the experience of academic, clinical and pharmaceutical neuroscientists in a unique collaborative approach to provide a greater understanding of the relevance of animal models of neuropsychiatric disorders and their role as translational tools for the discovery of CNS drugs being developed for the treatment of these disorders. The focus of this three-volume series of essays is to present a consensual picture of the translational value of animal models from leading experts actively involved in the use of animal models for understanding fundamental neurobiology of CNS disorders and the application of this knowledge to CNS drug discovery, and clinical investigators involved in clinical trials, drug development and eventual registration of novel pharmaceuticals. Each volume of the Animal and Translational Models for CNS Drug Discovery series is dedicated to the development and use of animal models in key therapeutic areas in psychiatric, neurologic and reward deficit disorders. Each volume has introductory chapters expressing the view of the role and relevance of animal models for CNS drug discovery and development from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in relevant therapeutic areas and discusses the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Each volume is available for purchase individually.
Author: W.F. Gattaz
Publisher: Springer Science & Business Media
ISBN: 3798519536
Category : Medical
Languages : en
Pages : 492
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Book Description
- The topics covered in the six sections of the book are Epidemiology and Environment, Precursors, Pathophysiological Mechanisms, Genetics, Controversies in Schizophrenia, and Treatment. - Reflects the progress made on Schizophrenia since 1986.
