The Chemistry of Process Development in Fine Chemical and Pharmaceutical Industry PDF Download
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Author: Someswara Rao
Publisher: John Wiley & Sons
ISBN: 047031995X
Category : Technology & Engineering
Languages : en
Pages : 1
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Book Description
This book brings together the chemical strategies used in the optimisation of organic reactions and processes, and highlights the practical and technological options available. This book offers: an encyclopedic treatment of organic chemistry from an industrial, process research and development, and manufacturing point of view plenty of examples to illustrate the scope and limitation of the strategies a comprehensive index organised by topic, reaction type, and reagent an extensive literature survey. This is an essential and comprehensive guide for experienced practitioners of chemical process research and development, fresh recruits to chemical industry R&D divisions, and academics who are interested in interacting with the chemical industry, optimising their synthetic strategies, and enriching the field of atom economy.
Author: Someswara Rao
Publisher: John Wiley & Sons
ISBN: 047031995X
Category : Technology & Engineering
Languages : en
Pages : 1
Get Book
Book Description
This book brings together the chemical strategies used in the optimisation of organic reactions and processes, and highlights the practical and technological options available. This book offers: an encyclopedic treatment of organic chemistry from an industrial, process research and development, and manufacturing point of view plenty of examples to illustrate the scope and limitation of the strategies a comprehensive index organised by topic, reaction type, and reagent an extensive literature survey. This is an essential and comprehensive guide for experienced practitioners of chemical process research and development, fresh recruits to chemical industry R&D divisions, and academics who are interested in interacting with the chemical industry, optimising their synthetic strategies, and enriching the field of atom economy.
Author: C. Someswara Rao
Publisher:
ISBN: 9788186299500
Category : Chemical engineering
Languages : en
Pages : 1277
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Book Description
Author: C. Somerswara Rao
Publisher:
ISBN: 9788186299777
Category : Chemical engineering
Languages : en
Pages : 1311
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Book Description
This Book Offers:* An Encyclopedic Treatment Of Organic Chemistry From An Industrial, Process Research And Development, And Manufacturing Point Of View * Plenty Of Examples To Illustrate The Scope And Limitation Of The Strategies* A Comprehensive Index Organised By Topic, Reaction Type, And Reagent And An Extensive Literature Survey.
Author: A. Cybulski
Publisher: Gulf Professional Publishing
ISBN: 0080542298
Category : Technology & Engineering
Languages : en
Pages : 566
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Book Description
The sector of fine chemicals, including pharmaceuticals, agrochemicals, dyes and pigments, fragrances and flavours, intermediates, and performance chemicals is growing fast. For obvious reasons chemistry is a key to the success in developing new processes for fine chemicals. However, as a rule, chemists formulate results of their work as recipes, which usually lack important information for process development. Fine Chemicals Manufacture, Technology and Engineering is intended to show what is needed to make the recipe more useful for process development purposes and to transform the recipe into an industrial process that will be safe, environmentally friendly, and profitable.The goal of this book is to form a bridge between chemists and specialists of all other branches involved in the scale-up of new processes or modification of existing processes with both a minimum effort and risk and maximum profit when commercializing the process. New techniques for scale-up and optimization of existing processes and improvements in the utilization of process equipment that have been developed in recent years are presented in the book.
Author: Derek Walker
Publisher: John Wiley & Sons
ISBN: 0470259507
Category : Medical
Languages : en
Pages : 424
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Book Description
Here is a practical guide that not only presents insights into the organization and management of the disciplines involved in chemical process development but also provides basic knowledge of these disciplines, enabling process development practitioners to recognize and assimilate them in their work. This book illustrates practical considerations through many examples of the successful direction and integration of the activities of chemists, analysts, chemical engineers, and biologists, as well as safety, regulatory, and environmental professionals in productive teams. Moreover, this reference provides guidance on: Directing and carrying out specific tasks and courses of action Making and communicating clear and achievable decisions Solving problems on the spot Managing the administrative aspects of chemical process development The author, Dr. Derek Walker, has directed chemical process development work for four decades, combining firsthand chemical synthesis experience with many other disciplines needed to create chemical processes. You will benefit from his advice and unique insights into: Understanding the workings of matrix organizations Defining missions and creating action plans Developing interdisciplinary approaches to problem solving Holding review meetings, revising goals, and motivating staff Prioritizing programs and responses to emergencies In addition, you'll learn how successful chemists, in collaboration with other disciplines, define the best (green) chemistry for process scale-up, including accommodating FDA requirements in the last process steps and addressing safety and environmental matters early in their work. Case studies provide incisive perspective on these issues. A chapter on recognizing and patenting intellectual property emphasizes the importance of comprehensive literature surveys and understanding invention. A chapter on the future challenges you to think beyond narrow constraints and explore new horizons.
Author: Kumar Gadamasetti
Publisher: CRC Press
ISBN: 9780824719814
Category : Medical
Languages : en
Pages : 514
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Book Description
Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.
Author: A. John Blacker
Publisher: Royal Society of Chemistry
ISBN: 1849731462
Category : Medical
Languages : en
Pages : 375
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Book Description
'Pharmaceutical Process Development' is aimed at both graduates and postgraduates interested in a career in the pharmaceutical industry and informs them about the breadth of the work carried out in chemical research and development departments.
Author: Stan A. Lee
Publisher:
ISBN: 9780191849206
Category : Chemical engineering
Languages : en
Pages : 88
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Book Description
This book is largely derived from the study of compounds undergoing development as novel pharmaceutical agents within the Process Development laboratories of the Pharmaceuticals Division of ICI (Imperial Chemical Industries) and latterly within Zeneca Pharmaceuticals.
Author: Neal G. Anderson
Publisher: Academic Press
ISBN: 0123865387
Category : Science
Languages : en
Pages : 489
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Book Description
Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights:• Reflects the current thinking in chemical process R&D for small molecules• Retains similar structure and orientation to the first edition. • Contains approx. 85% new material• Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up)• Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes)• Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes
Author: Neal G. Anderson
Publisher: Academic Press
ISBN: 9781483299778
Category : Science
Languages : en
Pages : 354
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Book Description
This book provides a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students. * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more * Includes over 100 tips for rapid process development * Presents guidelines for implementing and troubleshooting processes
