Cinnolines and Phthalazines, Supplement 2

Cinnolines and Phthalazines, Supplement 2 PDF Author: Desmond J. Brown
Publisher: John Wiley & Sons
ISBN: 0471744115
Category : Science
Languages : en
Pages : 499

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Book Description
This book provides the most comprehensive, current reference on the synthetic chemistry of cinnolines and phthalazines. Applications to the syntheses of natural products and other chiral compounds are described. Volume 64 contains chapters exploring the following topics: * Primary Syntheses of Cinnolines * Cinnoline, Alklycinnolines, and Arylcinnolines * Halogenocinnolines * Oxycinnolines * Thiocinnolines * Nitro-, Amino-, and Related Cinnolines * Cinnolinecarboxylic Acids and Related Derivatives * Primary Syntheses of Phthalazines * Phthalazine, Alklyphthalazines, and Arylphthalazines * Halogenophthalazines * Oxyphthalazines * Thiophthalazines * Phthalazinecarboxylic Acids and Related Derivatives * An Appendix of Tables of Simple Cinnolines and Simple Phthalazines

Cinnolines and Phthalazines, Supplement 2

Cinnolines and Phthalazines, Supplement 2 PDF Author: Desmond J. Brown
Publisher: John Wiley & Sons
ISBN: 0471744115
Category : Science
Languages : en
Pages : 499

Get Book Here

Book Description
This book provides the most comprehensive, current reference on the synthetic chemistry of cinnolines and phthalazines. Applications to the syntheses of natural products and other chiral compounds are described. Volume 64 contains chapters exploring the following topics: * Primary Syntheses of Cinnolines * Cinnoline, Alklycinnolines, and Arylcinnolines * Halogenocinnolines * Oxycinnolines * Thiocinnolines * Nitro-, Amino-, and Related Cinnolines * Cinnolinecarboxylic Acids and Related Derivatives * Primary Syntheses of Phthalazines * Phthalazine, Alklyphthalazines, and Arylphthalazines * Halogenophthalazines * Oxyphthalazines * Thiophthalazines * Phthalazinecarboxylic Acids and Related Derivatives * An Appendix of Tables of Simple Cinnolines and Simple Phthalazines

The Chemistry of Heterocyclic Compounds

The Chemistry of Heterocyclic Compounds PDF Author: D. J. Brown
Publisher:
ISBN:
Category : Chemistry of heterocyclic compounds
Languages : en
Pages : 420

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Book Description


Chemistry of Heterocyclic Compounds

Chemistry of Heterocyclic Compounds PDF Author: D. J. Brown
Publisher:
ISBN:
Category : Heterocyclic compounds
Languages : en
Pages : 460

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Book Description


Amino Acids: Insights and Roles in Heterocyclic Chemistry

Amino Acids: Insights and Roles in Heterocyclic Chemistry PDF Author: Zerong Wang
Publisher: CRC Press
ISBN: 1000738922
Category : Science
Languages : en
Pages : 420

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Book Description
This is the second volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on α-amino acids, the potential challenges in working with α-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from alpha-amino acids. These heterocyclic compounds include hydantoins, thiohydantoins (including 2-thiohydantoins, 4-thiohydantoins, 2,4-dithiohydantoins), 2,5-diketopiperazines, N-carboxyanhydrides, N-thiocarboxyanhydrides, sydnones, sydnonimines, azlactones, pseudoazlactones, and oxazolidin-5-ones. This is the first resource to comprehensively collect all the heterocycles that can be directly prepared from α-amino acids. In addition, almost all kinds of synthetic methods for a particular type of heterocycles from alpha-amino acids are included, along with the detailed mechanistic discussions and experimental procedures. In Volume 2: Hydantoins, Thiohydantoins, and 2,5-Diketopiperazines compiles the three IUPAC accepted nomenclature systems for heterocyclic compounds, which will be very useful for readers working in the heterocyclic chemistry field for giving synthesized molecules their correct names. In addition, three groups of heterocyclic compounds, i.e., hydantoins, thiohydantoins (including 2-thiohydantoin, 4-thiohydantoin and 2,4-dithiohydantoin), and 2,5-diketopiperazines, have been organized with updated literature information. Particularly, all three groups of heterocyclic compounds have demonstrated many important biological activities, particularly anticancer and antibacterial activities. On the other hand, these three groups of heterocycles can be applied as substrates to make other chemical derivatives, particularly novel unnatural amino acids. All their reactivities have been compiled and updated. The other volumes include: Volume 1: Protecting Groups Volume 3: N-Carboxyanhydrides, N-Thiocarboxyanhydrides, and Sydnones Volume 4: Azlactones and Oxazolidin-5-ones All together, this unique 4-volume set thoroughly covers the two types of heterocyclic compounds that are originated from alpha-amino acids, providing carefully compiled updated information with detailed examples. The author has shared many thoughtful insights based on his strong background in physical organic chemistry. The volumes will be highly valuable for graduate students and senior students, as well as for professors and researchers working in the field of medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, and proteins and peptides.

The Naphthyridines

The Naphthyridines PDF Author: Desmond J. Brown
Publisher: John Wiley & Sons
ISBN: 047018115X
Category : Science
Languages : en
Pages : 448

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Book Description
A volume in the Chemistry of Heterocyclic Compounds series, this book provides a summary of the chemistry of each of the six naphthyridine systems along with tables of known simple derivatives with original references. Each of the six naphthyridine systems are described in valuable detail and coverage includes: Primary synthetic methods from non-naphthyridine substrates; Chemistry and properties of the parent heterocycle and its simple alkyl derivatives; Formation and reactions of halogeno derivatives; formation and reactions of hydroxy, oxo, alkoxy, and related derivatives.

Chromenes, Chromanones, and Chromones, Volume 31

Chromenes, Chromanones, and Chromones, Volume 31 PDF Author: Gwynn P. Ellis
Publisher: John Wiley & Sons
ISBN: 0470188529
Category : Science
Languages : en
Pages : 1213

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Book Description
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Introduction to Heterocyclic Chemistry

Introduction to Heterocyclic Chemistry PDF Author: Peter A. Jacobi
Publisher: John Wiley & Sons
ISBN: 1119417686
Category : Science
Languages : en
Pages : 306

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Book Description
A unique approach to a core topic in organic chemistry presented by an experienced teacher to students and professionals Heterocyclic rings are present in the majority of known natural products, contributing to enormous structural diversity. In addition, they often possess significant biological activity. Medicinal chemists have embraced this last property in designing most of the small molecule drugs in use today. This book offers readers a fundamental understanding of the basics of heterocyclic chemistry and their occurrence in natural products such as amino acids, DNA, vitamins, and antibiotics. Based on class lectures that the author has developed over more than 40 years of teaching, it focuses on the chemistry of such heterocyclic substances and how they differ from carbocyclic systems. Introductory Heterocyclic Chemistry offers in-depth chapters covering naturally occurring heterocycles; properties of aromatic heterocycles; π-deficient heterocycles; π-excessive heterocycles; and ring transformations of heterocycles. It then offers an overview of 1,3-dipolar cycloadditions before finishing up with a back-to-basics section on nitriles and amidines. Presents a conversational approach to a fundamental topic in organic chemistry teaching Offers a unique look at this core organic chemistry topic via important naturally occurring and/or biologically active heterocycles Based on the author's many years of class lectures for teaching at the undergraduate and graduate level as well as pharmaceutical-industry courses Clear, concise, and accessible for advanced students of chemistry to gain a fundamental understanding of the basics of heterocyclic chemistry Introductory Heterocyclic Chemistry is an excellent text for undergraduate and graduate students as well as chemists in industrial environments in chemistry, pharmacy, medicinal chemistry, and biology.

Condensed Pyridazines Including Cinnolines and Phthalazines, Volume 27

Condensed Pyridazines Including Cinnolines and Phthalazines, Volume 27 PDF Author: Raymond N. Castle
Publisher: John Wiley & Sons
ISBN: 0470188480
Category : Science
Languages : en
Pages : 1137

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Book Description
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

An Introduction to the Chemistry of Heterocyclic Compounds

An Introduction to the Chemistry of Heterocyclic Compounds PDF Author: Richard Morrin Acheson
Publisher: John Wiley & Sons
ISBN:
Category : Science
Languages : en
Pages : 538

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Book Description


Second Supplements [sic] to the 2nd Edition of Rodd's Chemistry of Carbon Compounds

Second Supplements [sic] to the 2nd Edition of Rodd's Chemistry of Carbon Compounds PDF Author: Malcolm Sainsbury
Publisher:
ISBN:
Category : Carbon compounds
Languages : en
Pages : 320

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Book Description