The Chemistry and Biology of Antibiotics

The Chemistry and Biology of Antibiotics PDF Author: Vladimír Betina
Publisher: Elsevier Science & Technology
ISBN:
Category : Medical
Languages : en
Pages : 600

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Book Description

The Chemistry and Biology of Antibiotics

The Chemistry and Biology of Antibiotics PDF Author: Vladimír Betina
Publisher: Elsevier Science & Technology
ISBN:
Category : Medical
Languages : en
Pages : 600

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Book Description


Chemistry of Antibiotics and Related Drugs

Chemistry of Antibiotics and Related Drugs PDF Author: Mrinal K. Bhattacharjee
Publisher: Springer Nature
ISBN: 303107582X
Category : Science
Languages : en
Pages : 276

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Book Description
This textbook builds on the success of the earlier edition, offering alternative strategies for discovering new antibiotics. It discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. It also covers the global action plan on antimicrobial resistance from the World Health Organization and discusses several Antibiotic Stewardship Programs adopted by agencies at local levels. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, the book is self-contained and written in accessible language. It includes all necessary background biochemistry material and a discussion of the latest developments in the field of antibiotics. Original research works are frequently cited and experimental procedures and interpretation of results are emphasized.

Aminoglycoside Antibiotics

Aminoglycoside Antibiotics PDF Author: Dev P. Arya
Publisher: John Wiley & Sons
ISBN: 047174302X
Category : Science
Languages : en
Pages : 338

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Book Description
Advances that open new avenues in developing aminoglycoside antibiotics During the last twenty years, there have been numerous advances in the understanding of the chemistry, biochemistry, and recognition of aminoglycosides. This has led to the development of novel antibiotics and opened up new therapeutic targets for intervention. This is the first book to provide a complete overview of recent advances in the field and explore their tremendous potential for drug discovery and rational drug design. With chapters written by one or more leading experts in their specialty areas, the book addresses the chemistry, biology, and toxicology of aminoglycosides. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery is a great resource for academic and industrial researchers in drug design and mechanism studies and for researchers studying antibiotic resistance, antibiotic design and synthesis, and the discovery of novel pharmaceuticals. It is also a valuable reference for graduate students in pharmacy, pharmaceutical science, biophysics, medicinal chemistry, and chemical biology.

Chemistry and Biology of [beta]-lactam Antibiotics

Chemistry and Biology of [beta]-lactam Antibiotics PDF Author: Robert B. Morin
Publisher:
ISBN: 9780125063029
Category : Medical
Languages : en
Pages : 430

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Biochemistry and Molecular Biology of Antimicrobial Drug Action

Biochemistry and Molecular Biology of Antimicrobial Drug Action PDF Author: T. J. Franklin
Publisher: Springer Science & Business Media
ISBN: 1475745990
Category : Medical
Languages : en
Pages : 173

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Book Description
The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Macrolide Antibiotics

Macrolide Antibiotics PDF Author: Satoshi Omura
Publisher: Academic Press
ISBN: 9780125264518
Category : Medical
Languages : en
Pages : 668

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Book Description
Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifungal research and treament.

Antibiotics

Antibiotics PDF Author: Christopher Walsh
Publisher: John Wiley & Sons
ISBN: 1555819311
Category : Medical
Languages : en
Pages : 477

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Book Description
A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.

Biochemistry and Molecular Biology of Antimicrobial Drug Action

Biochemistry and Molecular Biology of Antimicrobial Drug Action PDF Author: Trevor J. Franklin
Publisher: Springer Science & Business Media
ISBN: 0387225544
Category : Medical
Languages : en
Pages : 188

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Book Description
The subject is one of major interest in basic microbiology and infectious diseases and the book is a known classic.

Molecules and Medicine

Molecules and Medicine PDF Author: E. J. Corey
Publisher: John Wiley & Sons
ISBN: 1118361733
Category : Science
Languages : en
Pages : 272

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Book Description
Molecules and Medicine provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine. It delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules in use in modern medicine. Opening sections of the book provide a unique, clear, and concise introduction, which enables readers to understand chemical formulas.

Beyond the Molecular Frontier

Beyond the Molecular Frontier PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309168392
Category : Science
Languages : en
Pages : 238

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Book Description
Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.