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Author: Howard M. Eisenberg
Publisher: Springer Science & Business Media
ISBN: 1468437526
Category : Medical
Languages : en
Pages : 340
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Book Description
As traced by Uichael Bradbury in his recently published monograph, The Concept of a BZood-Brain Barrier, the idea of a scientific challenge is just about as old as the twentieth century. Curiously, it remains undefined. Is it a structure or structures as some use the term, or is it a reciprocal per meability, a force-flow relationship, as do others, or is it a group of processes, some more specialized than others? Depend ing upon the observer, the method, and what is observed, it seems to be each of these or all. This Symposium takes as its focus of interest the micro vasculature of the brain and includes considerations of blood flow, the properties of vessel walls and the control of flow and permeability. In addition perturbations that change the characteristics of the flow of materials are given attention. By changing the usual focus of interest, the organizers, Drs. Suddith and Eisenberg, have given a fresh outlook to the subject and now, by publication of the Proceedings, have arranged for wide availability of these interesting papers. Keasley Welch v PREFACE A symposium on the cerebral microvasculature and its function in the blood-brain barrier was held at The University of Texas Medical Branch, Galveston, in the summer of 1979. Investigators from the United States and Europe met to discuss their recent work.
Author: Howard M. Eisenberg
Publisher: Springer Science & Business Media
ISBN: 1468437526
Category : Medical
Languages : en
Pages : 340
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Book Description
As traced by Uichael Bradbury in his recently published monograph, The Concept of a BZood-Brain Barrier, the idea of a scientific challenge is just about as old as the twentieth century. Curiously, it remains undefined. Is it a structure or structures as some use the term, or is it a reciprocal per meability, a force-flow relationship, as do others, or is it a group of processes, some more specialized than others? Depend ing upon the observer, the method, and what is observed, it seems to be each of these or all. This Symposium takes as its focus of interest the micro vasculature of the brain and includes considerations of blood flow, the properties of vessel walls and the control of flow and permeability. In addition perturbations that change the characteristics of the flow of materials are given attention. By changing the usual focus of interest, the organizers, Drs. Suddith and Eisenberg, have given a fresh outlook to the subject and now, by publication of the Proceedings, have arranged for wide availability of these interesting papers. Keasley Welch v PREFACE A symposium on the cerebral microvasculature and its function in the blood-brain barrier was held at The University of Texas Medical Branch, Galveston, in the summer of 1979. Investigators from the United States and Europe met to discuss their recent work.
Author: F. Hammersen
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318040754
Category : Medical
Languages : en
Pages : 113
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Book Description
Author: Marilyn J. Cipolla
Publisher: Biota Publishing
ISBN: 1615047239
Category : Medical
Languages : en
Pages : 82
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Book Description
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Author: Anthony Marmarou
Publisher: Springer Science & Business Media
ISBN: 9783211830949
Category : Medical
Languages : en
Pages : 472
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Book Description
This volume contains the most recent works on intracranial pressure and neuromonitoring in brain injury selected from 300 abstracts submitted to the 10th International Symposium on Intracranial Pressure. It includes state of the art monitoring of the brain injured patient in intensive care as well as the current state of knowledge in neurochemical and oxygen monitoring of the injured brain. Recent advances in molecular mechanisms of injury and the pathophysiology of ischemia and trauma are also included. "... this publication presents a comprehensive survey of the present state of art in the field and thus gives directions for further research to those engaged in ICP measurement and neuromonitoring”. Intensive Care Med
Author:
Publisher: Elsevier
ISBN: 012805154X
Category : Medical
Languages : en
Pages : 2854
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Book Description
Encyclopedia of Cardiovascular Research and Medicine, Four Volume Set offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focused basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine. Presents comprehensive coverage of every aspect of cardiovascular medicine and research Offers readers a broad, interdisciplinary overview of the concepts in cardiovascular research and medicine with applications across biomedical research Includes reputable, foundational content on genetics, cancer, immunology, cell biology and molecular biology Provides a multi-media enriched color-illustrated text with high quality images, graphs and tables.
Author: K. Michael Welch
Publisher: Academic Press
ISBN: 0127431705
Category : Medical
Languages : en
Pages : 855
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Book Description
Primer on Cerebrovascular Diseases is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, and presents the information in a comprehensive and easily accessible manner. The book also contains valuable information on practical applications of basic research. Presents topics in a comprehensive and accessible format Written by international authorities on cerebral vasculature Provides practical applications for researchers
Author: Leonardo Pantoni
Publisher: Cambridge University Press
ISBN: 1107031664
Category : Medical
Languages : en
Pages : 375
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Book Description
Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.
Author: Robert D. Stevens
Publisher: Cambridge University Press
ISBN: 1107434424
Category : Medical
Languages : en
Pages : 457
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Book Description
Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.
Author: Paul Kleihues
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 326
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Book Description
The second edition of this concise reference book was prepared by 106 authors from 21 countries and covers the neuro-oncological literature until January 2000. Diagnostic criteria, pathological features and associated genetic alterations are described in a strictly disease-oriented manner. Sections on more than 70 neoplasms and their variants include ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics and predictive factors. New disease entities include the chordoid glioma of the third ventricle and the cerebellar liponeurocytoma. Inherited tumor syndromes involving the nervous system are dealt with in a separate chapter, combining diagnostic criteria, pathology and genetics.
Author: Peter Lanzer
Publisher: Springer
ISBN: 9783642370779
Category : Medical
Languages : en
Pages : 5004
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Book Description
​Vascular management and care has become a truly multidisciplinary enterprise as the number of specialists involved in the treatment of patients with vascular diseases has steadily increased. While in the past, treatments were delivered by individual specialists, in the twenty-first century a team approach is without doubt the most effective strategy. In order to promote professional excellence in this dynamic and rapidly evolving field, a shared knowledge base and interdisciplinary standards need to be established. Pan Vascular Medicine, 2nd edition has been designed to offer such an interdisciplinary platform, providing vascular specialists with state-of-the art descriptive and procedural knowledge. Basic science, diagnostics, and therapy are all comprehensively covered. In a series of succinct, clearly written chapters, renowned specialists introduce and comment on the current international guidelines and present up-to-date reviews of all aspects of vascular care.
