The Cerebellum Revisited

The Cerebellum Revisited PDF Author: Rodolfo Llinas
Publisher: Springer Science & Business Media
ISBN: 1461228409
Category : Medical
Languages : en
Pages : 354

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Book Description
This book is organized into three parts that correspond with the main groups of chapters delivered during the Cajal Centenary Meeting on The Neutron Doctrine. These chapters represent important aspects of the morphology, development, and function of the cerebellum and related structures. Clearly an exhaustive analysis of all aspects of the cerebellar system, as they relate to the legacy of Ramon y Cajal, would be impossible to contain in just one volume, given its far-reaching impact. Instead, we deliberately steered away from the traditional handbook approach that some of us have taken in the past and selected those aspects of cerebellar research currently under vigorous study that would also represent the widest scope of interest for neuroscientists in general and for cerebellar specialists in particular. In particular, we felt that as the discrete anatomy of the cerebellum is quite well known, only certain aspects of the structure should be discussed here. For example, the organization of the pontocerebellar pathways, we felt, would be particularly interesting given the enormity of the system in higher vertebrates. Also of interest is the distribution and development of the synaptology and neurotransmitter properties in this cortex. Indeed, from the point of view of cerebellar development, this may represent one of the clearest paradigms in the understanding of rules for neurogenesis for the central nervous system.

The Cerebellum Revisited

The Cerebellum Revisited PDF Author: Rodolfo Llinas
Publisher: Springer Science & Business Media
ISBN: 1461228409
Category : Medical
Languages : en
Pages : 354

Get Book Here

Book Description
This book is organized into three parts that correspond with the main groups of chapters delivered during the Cajal Centenary Meeting on The Neutron Doctrine. These chapters represent important aspects of the morphology, development, and function of the cerebellum and related structures. Clearly an exhaustive analysis of all aspects of the cerebellar system, as they relate to the legacy of Ramon y Cajal, would be impossible to contain in just one volume, given its far-reaching impact. Instead, we deliberately steered away from the traditional handbook approach that some of us have taken in the past and selected those aspects of cerebellar research currently under vigorous study that would also represent the widest scope of interest for neuroscientists in general and for cerebellar specialists in particular. In particular, we felt that as the discrete anatomy of the cerebellum is quite well known, only certain aspects of the structure should be discussed here. For example, the organization of the pontocerebellar pathways, we felt, would be particularly interesting given the enormity of the system in higher vertebrates. Also of interest is the distribution and development of the synaptology and neurotransmitter properties in this cortex. Indeed, from the point of view of cerebellar development, this may represent one of the clearest paradigms in the understanding of rules for neurogenesis for the central nervous system.

The Cerebellum and Its Disorders

The Cerebellum and Its Disorders PDF Author: Mario Manto
Publisher: Cambridge University Press
ISBN: 9780521771566
Category : Medical
Languages : en
Pages : 620

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Book Description
The first comprehensive text on the cerebellum and its disorders for many years.

The Cerebellum and Cognition

The Cerebellum and Cognition PDF Author:
Publisher: Academic Press
ISBN: 0080857752
Category : Science
Languages : en
Pages : 709

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Book Description
The Cerebellum and Cognition pulls together a preeminent group of authors. The cerebellum has been previously considered as a highly complex structure involved only with motor control. The cerebellum is essential to nonmotor functions, and recent research has revealed new medically important roles of the cerebellum and cognitive processes. Selected for inclusion in Doody's Core Titles 2013, an essential collection development tool for health sciences libraries Comprehensive coverage of cerebellum in motor control and cognition New developments regarding the cerebellum and motor systems Therapeutic implications of cerebellar contributions to cognition Preeminent group of contributors

Cerebellum as a CNS Hub

Cerebellum as a CNS Hub PDF Author: Hidehiro Mizusawa
Publisher: Springer Nature
ISBN: 3030758176
Category : Medical
Languages : en
Pages : 543

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Book Description
Based on the 75th Fujihara Seminar held in December 2018 in Tokyo, Japan, this volume explores the latest research on the cerebellum. Contributors seek to examine the cerebellum's role as a unique hub for brain activity and discover new information about its purpose. The discussion is broad, ranging from evolutionary topics to therapeutic strategy and addresses both physiology and pathology. Subjects covered include anatomy, information processing, complex spikes, plasticity, modeling, and spinocerebellar ataxias. The volume is intended to set the stage for the future of cerebellar research and guide both basic and clinical researchers.

Creating Coordination in the Cerebellum

Creating Coordination in the Cerebellum PDF Author: Chris I. De Zeeuw
Publisher: Elsevier
ISBN: 0080457207
Category : Science
Languages : en
Pages : 430

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Book Description
Creating Coordination in the Cerebellum provides a multidisciplinary collection of chapters on the cerebellum with topics covering the entire spectrum from development and molecular neurobiology, cell physiology and plasticity to motor control, system physiology, functional imaging and pathology. The book not only presents novel discoveries obtained with recently developed technologies, but also gives new general concepts in global issues of cerebellar development and functions. By doing so it sets the standard for cerebellar research of the 21st century. * Provides a complete overview of current cerebellar research * Includes color illustrations * Contains contributions from renowned cerebellar scientists

The Neuronal Codes of the Cerebellum

The Neuronal Codes of the Cerebellum PDF Author: Detlef Heck
Publisher: Academic Press
ISBN: 0128016752
Category : Psychology
Languages : en
Pages : 282

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Book Description
The Neuronal Codes of the Cerebellum provides the most updated information on what is known on the topics of the cerebellum’s anatomy and single cell physiology, two areas where there has been a gap in knowledge regarding the specific codes it uses to process information internally and convey commands to other brain regions. This has created difficulties for researchers and clinicians looking to develop an understanding of the mechanisms by which it contributes to behavior and how its dysfunction causes neurological symptoms. Focused on findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes, this edited volume will aid scientists in overcoming that knowledge gap, also serving as the first resource to broadly address the different aspects of spike coding in the cerebellum that focuses on spike train analysis. Compiles current knowledge about functioning of the cerebellum on a cellular basis and how information is encoded in the cerebellum Highlights findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes Contents include an introduction to the cerebellum and experimental/theoretical techniques, as well as the function of cerebral coding during disorder, learning, behavior generation, motor behavior, and more Bridges the gap for cerebellar researchers between single cell biophysics/anatomic studies and behavioral studies Incorporates various in vivo approaches with different behavioral paradigms in primates and rodents, modeling studies of coding, and in vitro approaches

Motor Learning and Synaptic Plasticity in the Cerebellum

Motor Learning and Synaptic Plasticity in the Cerebellum PDF Author: Paul J. Cordo
Publisher: Cambridge University Press
ISBN: 9780521597050
Category : Medical
Languages : en
Pages : 78

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Book Description
This book is concerned with the involvement of the cerebellum in learning and remembering motor tasks. It is unique in discussing plasticity at both the cellular and at the behavioral level.

Development of the Cerebellum from Molecular Aspects to Diseases

Development of the Cerebellum from Molecular Aspects to Diseases PDF Author: Hassan Marzban
Publisher: Springer
ISBN: 3319597493
Category : Medical
Languages : en
Pages : 502

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Book Description
The authors present the most current and cutting-edge knowledge regarding the molecular basis of cerebellar development, focusing on information relevant to laboratory scientists and clinicians providing service to patients with cerebellar disorders. Knowledge obtained from advanced neuroimaging techniques that are used during development, and from molecular- and genetic-based studies has provided rapidly-growing evidence that the cerebellum is a brain region that is highly impacted by developmental defects. Cerebellar defects result in significant intellectual and motor function impairment that affects both the patients and their families.

Translational Medicine

Translational Medicine PDF Author: Robert A. Meyers
Publisher: John Wiley & Sons
ISBN: 352768719X
Category : Science
Languages : en
Pages : 1100

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Book Description
This reference work gives a compete overview of the different stages of drug development using a translational approach. The book is structured in different parts, following the different stages in drug development. Almost half of the work is dedicated to core of drug discovery using a translational approach, the identification of appropriate targets and screening methods for the identification of compounds interacting with these targets. The rest of book covers the whole downstream pipeline after the identification of lead compounds, such as bioavailability issues, identification of appropriate drug delivery venues, production and scaling issues and preclinical trials. As has been the case with other works in the encyclopedia, the book is made up of long, comprehensive and authoritative chapters, written by outstanding researchers in the field.

Cerebellar Functions

Cerebellar Functions PDF Author: J. Bloedel
Publisher: Springer Science & Business Media
ISBN: 3642699804
Category : Medical
Languages : en
Pages : 346

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Book Description
Over the past few semesters a group of neurologists, neurophysiologists, and brain theorists in various departments of Tlibingen University have gathered periodically in an effort to review ideas and evidence on cerebel lar functions. At times, general solutions seemed close, when credit was given to various theoretical proposals advanced since the early days of cer ebellar physiology, however, it became clear in every case that a large part of the available facts refused to submit to the general ideas. As believers in the power of scientific discussion, we felt that the time was ripe for posing the problem of the cerebellum once more to a well articulated group of specialists that would include proponents of every disparate point of view. The sponsorship of the Max Planck Society and of the Deutsche Forschungsgemeinschaft, to whom we express our profound gratitude, made it possible to organize an international meeting in Septem ber, 1983. The aim of making new, even extravagant ideas palatable to each other was well accomplished by the participants. We trust that some of the ensuing excitement has been carried over into the printed version.