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Author: Akbar Dorgalaleh
Publisher: Springer
ISBN: 3319767232
Category : Medical
Languages : en
Pages : 397
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Book Description
This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Author: Akbar Dorgalaleh
Publisher: Springer
ISBN: 3319767232
Category : Medical
Languages : en
Pages : 397
Get Book Here
Book Description
This book describes in detail the clinical presentation, diagnosis, and management of a wide range of congenital bleeding disorders. It will assist readers in overcoming the significant challenges involved in clinical and laboratory diagnosis and in providing effective clinical care that makes optimal use of new products, including recombinant factor concentrate. The coverage ranges from hemophilia A and B and von Willebrand disease to rare bleeding disorders such as congenital factor V, factor X, factor XI, and factor XIII deficiency and inherited platelet function disorders. The exceptional attention to rarer conditions is of particular importance given the considerable risk of overlooking them during diagnosis, with potential consequences for disease-related morbidity and mortality. The authors are acknowledged specialists in the field from across the world who have particular expertise in the disorder that they discuss. The book will be of value to hematologists, oncologists, pediatricians, laboratory specialists and technicians, general physicians, and trainees.
Author: Robert Fitridge
Publisher: University of Adelaide Press
ISBN: 1922064009
Category : Medical
Languages : en
Pages : 589
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Book Description
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Author: John Terborgh
Publisher: Island Press
ISBN: 1597268194
Category : Science
Languages : en
Pages : 487
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Book Description
Trophic cascades—the top-down regulation of ecosystems by predators—are an essential aspect of ecosystem function and well-being. Trophic cascades are often drastically disrupted by human interventions—for example, when wolves and cougars are removed, allowing deer and beaver to become destructive—yet have only recently begun to be considered in the development of conservation and management strategies. Trophic Cascades is the first comprehensive presentation of the science on this subject. It brings together some of the world’s leading scientists and researchers to explain the importance of large animals in regulating ecosystems, and to relate that scientific knowledge to practical conservation. Chapters examine trophic cascades across the world’s major biomes, including intertidal habitats, coastal oceans, lakes, nearshore ecosystems, open oceans, tropical forests, boreal and temperate ecosystems, low arctic scrubland, savannas, and islands. Additional chapters consider aboveground/belowground linkages, predation and ecosystem processes, consumer control by megafauna and fire, and alternative states in ecosystems. An introductory chapter offers a concise overview of trophic cascades, while concluding chapters consider theoretical perspectives and comparative issues. Trophic Cascades provides a scientific basis and justification for the idea that large predators and top-down forcing must be considered in conservation strategies, alongside factors such as habitat preservation and invasive species. It is a groundbreaking work for scientists and managers involved with biodiversity conservation and protection.
Author: Jovan P. Antovic
Publisher: John Wiley & Sons
ISBN: 1118327667
Category : Medical
Languages : en
Pages : 168
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Book Description
A practical guide to laboratory diagnosis and treatment of hemostatic disorders. This concise book distils the most clinically up-to-date information on thrombotic and bleeding disorders, including the latest treatment strategies, for key conditions and diseases. Essential Guide to Blood Coagulation covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders. Faced with a bleeding patient, it may be difficult to determine whether blood loss is due to a local factor, or an underlying hemostatic defect. There are a range of laboratory tests which can be performed to identify the cause of bleeding in a patient. This book highlights the tests that can be used in the laboratory to aid diagnosis. Essential Guide to Blood Coagulation has been updated to include the new anticoagulants and now has a dedicated chapter on antiplatelet drugs. This invaluable guide will help all those treating patients to expand their knowledge of hemostatic disorders. TITLES OF RELATED INTEREST Hemophilia and Hemostasis: A Case-Based Approach to Management Second Edition Alice Ma, Harold Roberts, Miguel Escobar ISBN: 978-0-470-65976-2 Quality in Laboratory Hemostasis and Thrombosis Second Edition Steve Kitchen, John Olson, Eric Preston (due May 2013) ISBN: 978-0-470-67119-1
Author: Jean-Paul Renaud
Publisher: John Wiley & Sons
ISBN: 1118900502
Category : Medical
Languages : en
Pages : 1367
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Book Description
With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins
Author: Cees Smit Sibinga
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 296
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Book Description
Proceedings of the Fifteenth Annual Symposium on Blood Transfusion, Groningen 1990, organized by the Red Cross Blood Bank, Groningen-Drenthe
Author: Stephen R. Carpenter
Publisher: Cambridge University Press
ISBN: 9780521566841
Category : Nature
Languages : en
Pages : 404
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Book Description
This 1993 book documents the importance of trophic cascades in aquatic ecology.
Author: Nils U. Bang
Publisher: Academic Press
ISBN: 148326128X
Category : Health & Fitness
Languages : en
Pages : 571
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Book Description
Thrombosis and Bleeding Disorders compiles the laboratory and research aspects of thrombosis and hemorrhagic disorders in humans. This book presents reviews of the underlying theory, physiology, and biochemistry of hemostasis and thrombosis, including the enzymology of blood coagulation and fibrinolysis. This compilation is divided into three levels of specific purposes. First is to provide the most reliable and widely accepted laboratory assays of undisputed diagnostic clinical value, which provides newcomers in the field and experienced workers in the coagulation laboratory with a reference manual to everyday work in a clinically-oriented environment. Second is to review and sketch in outline the theoretical sections focusing on mechanisms. Finally, this text aims to include a systematic review of the most successful purification techniques for individual coagulation factors and moieties of the fibrinolytic enzyme system. This publication is beneficial to medical students and clinicians concerned with human blood coagulation.
Author: Riccardo Proietti
Publisher: Springer Nature
ISBN: 3030744620
Category : Medical
Languages : en
Pages : 283
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Book Description
This book concisely covers the latest developments in the application of direct oral anticoagulants (DOACs) within cardiovascular medicine. It details the pharmacodynamics and pharmacokinetic mechanisms of DOACs and their application in treating patients with conditions ranging from coronary heart disease through kidney disease and cancer, including their perioperative management. Direct Oral Anticoagulants: From Pharmacology to Clinical Practice systematically describes the underlying mechanisms associated with DOACs and their use to treat a range of conditions and is an indispensable resource for all trainee and practicing physicians in a range of disciplines seeking a concise up-to-date resource on the topic.
Author: Sterling T. Bennett
Publisher: Springer
ISBN: 3319089242
Category : Medical
Languages : en
Pages : 210
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Book Description
Coagulation testing is the basis for the diagnosis of bleeding and thrombotic disorders, as well as the mainstay of anticoagulant monitoring and management. This handbook provides practical information and guidance on topics relevant to directing a coagulation laboratory, filling a void in the literature. Since the first edition, all chapters have been updated and an entirely new chapter is included on pharmacogenomics and pharmacogenetics. The book will aid pathologists, clinical laboratory scientists and other physicians serving as laboratory directors to understand and carry out their responsibilities. It will also assist residents and fellows in learning the basics of coagulation testing and serve as a useful day-to-day reference for coagulation laboratory supervisors, technologists, and technicians. Finally, clinicians may find aspects of the book helpful in understanding the role of the coagulation laboratory in patient evaluation and monitoring.
