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Author: Urs Albrecht
Publisher: Springer Science & Business Media
ISBN: 1441912622
Category : Science
Languages : en
Pages : 306
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Book Description
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Author: Urs Albrecht
Publisher: Springer Science & Business Media
ISBN: 1441912622
Category : Science
Languages : en
Pages : 306
Get Book Here
Book Description
With the invitation to edit this volume, I wanted to take the opportunity to assemble reviews on different aspects of circadian clocks and rhythms. Although most c- tributions in this volume focus on mammalian circadian clocks, the historical int- duction and comparative clocks section illustrate the importance of various other organisms in deciphering the mechanisms and principles of circadian biology. Circadian rhythms have been studied for centuries, but only recently, a mole- lar understanding of this process has emerged. This has taken research on circadian clocks from mystic phenomenology to a mechanistic level; chains of molecular events can describe phenomena with remarkable accuracy. Nevertheless, current models of the functioning of circadian clocks are still rudimentary. This is not due to the faultiness of discovered mechanisms, but due to the lack of undiscovered processes involved in contributing to circadian rhythmicity. We know for example, that the general circadian mechanism is not regulated equally in all tissues of m- mals. Hence, a lot still needs to be discovered to get a full understanding of cir- dian rhythms at the systems level. In this respect, technology has advanced at high speed in the last years and provided us with data illustrating the sheer complexity of regulation of physiological processes in organisms. To handle this information, computer aided integration of the results is of utmost importance in order to d- cover novel concepts that ultimately need to be tested experimentally.
Author: Michael Smolensky
Publisher: Macmillan + ORM
ISBN: 1466891467
Category : Health & Fitness
Languages : en
Pages : 679
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Book Description
A medical breakthrough explained by the leading authority on the connection between health and your body clock Chronotherapy-adjusting the care of the body to coincide with the body's natural clock-is poised to be the next major revolution in medical science. An understanding and awareness of these rhythms will enable us to maximize the effects not only of medications and other treatments, but also of diets, exercise programs, and other daily routines. The Body Clock Guide to Better Health combines a detailed discussion of major issues such as sleep, exercise, and nutrition, with a comprehensive A-to-Z reference to specific disorders. Among the health concerns it addresses are AIDS, arthritis, asthma, ADD, backache, cancer, depression, diabetes, digestive problems, allergies, heart disease, chronic pain, sexual dysfunction, stroke, and complications from pregnancy. General chapters explore the big picture-including monthly cycles and life cycles-and provide invaluable advice on foods and dietary supplements, fitness, better sex, jet lag, and more. The first book to look at body rhythms from a practical perspective, The Body Clock Guide to Better Health offers readers the dual benefits of improving the treatment of specific conditions while boosting their overall health and wellness.
Author: P. H. Redfern
Publisher: Pharmaceutical Press
ISBN: 9780853694885
Category : Medical
Languages : en
Pages : 456
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Book Description
In nature, many physical processes are governed by the passage of time. The study of these processes - chronobiology - reveals rhythmic patterns which may be yearly, monthly, daily or more frequent. Novel drug delivery systems are currently being delivered that will release varying quantities of a drug at optimum times to coincide with these rhythmic patterns.Chronotherapeutics considers the pharmaceutical and therapeutic implications associated with biological clocks. The book presents a comprehensive discussion of specific diseases that are time dependent, and the drugs and new drug formulations that can be used as treatments.Written by leading international experts in the field, Chronotherapeutics provides up-to-date information on chronobiology for non-chronobiologists in pharmaceutical and medical sciences. Peter Redfern is Professor of Pharmacology at the University of Bath, UK.
Author: Christopher S. Colwell
Publisher: John Wiley & Sons
ISBN: 1118467787
Category : Medical
Languages : en
Pages : 405
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Book Description
Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.
Author: Satchin Panda, PhD
Publisher: Rodale Books
ISBN: 0593135903
Category : Health & Fitness
Languages : en
Pages : 290
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Book Description
When we eat may be as important as what we eat. Discover how to reset your body’s natural clock—from an award-winning circadian rhythm and aging researcher “A complete program to recalibrate your day/night activities, optimize sleep, lose weight, learn/work, and exercise.”—Valter Longo, PhD, internationally bestselling author of The Longevity Diet Most people typically wake up, get hungry for meals, and doze off in bed around the same time every day. But if you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. For some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock. Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It’s a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life-changing methods show you the keys to avoiding and alleviating chronic ailments like diabetes, cancer, and dementia, as well as digestive conditions like acid reflux, heartburn, and irritable bowel disease. In short, knowing your circadian code might just be the secret to turning back the clock and slowing down the aging process.
Author: Kat Martin
Publisher: ReadHowYouWant.com
ISBN: 1458746968
Category : Fiction
Languages : en
Pages : 182
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Book Description
Teddy Williams was eight years old that Christmas, too young to understand all the undercurrents swirling around him in the tiny Michigan town of Dreyerville. He wasn't able to value that Christmas for the miracle it truly was. Teddy only knew he wanted to buy the beautiful Victorian clock in the window of Tremont's Antiques as a gift for his grandmother, Lottie Sparks, a woman desperate to find him a home before her rapidly progressing Alzheimer's left him an orphan. Teddy didn't know that in trying to buy the clock he would meet Sylvia Winters and Joe Dixon, a couple, once in love, desperate to overcome the past. He didn't know he would form a friendship with his neighbors, Floyd and Doris Culver, two people struggling to revive their long-dead marriage. He didn't know that these people would fill his Christmas with magic and hope; that the love of his friends would change his world, and that he would forever change theirs.
Author: C. Bartsch
Publisher: Springer Science & Business Media
ISBN: 364259512X
Category : Medical
Languages : en
Pages : 979
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Book Description
The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.
Author: Leon Kreitzman
Publisher: Profile Books
ISBN: 1847653723
Category : Science
Languages : en
Pages : 288
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Book Description
Popular science at its most exciting: the breaking new world of chronobiology - understanding the rhythm of life in humans and all plants and animals. The entire natural world is full of rhythms. The early bird catches the worm -and migrates to an internal calendar. Dormice hibernate away the winter. Plants open and close their flowers at the same hour each day. Bees search out nectar-rich flowers day after day. There are cicadas that can breed for only two weeks every 17 years. And in humans: why are people who work anti-social shifts more illness prone and die younger? What is jet-lag and can anything help? Why do teenagers refuse to get up in the morning, and are the rest of us really 'larks' or 'owls'? Why are most people born (and die) between 3am-5am? And should patients be given medicines (and operations) at set times of day, because the body reacts so differently in the morning, evening and at night? The answers lie in our biological clocks the mechanisms which give order to all living things. They impose a structure that enables us to change our behaviour in relation to the time of day, month or year. They are reset at sunrise and sunset each day to link astronomical time with an organism's internal time.
Author: David J. Kerr
Publisher: Oxford University Press
ISBN: 0191065110
Category : Medical
Languages : en
Pages : 2837
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Book Description
Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309492319
Category : Medical
Languages : en
Pages : 175
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Book Description
Throughout history, perhaps no other disease has generated the level of social, scientific, and political discourse or has had the degree of cultural significance as cancer. A collective in the truest sense of the word, "cancer" is a clustering of different diseases that afflict individuals in different ways. Its burdens are equally broad and diverse, from the physical, financial, and psychological tolls it imposes on individuals to the costs it inflicts upon the nation's clinical care and public health systems, and despite decades of concerted efforts often referred to as the "war on cancer", those costs have only continued to grow over time. The causes and effects of cancer are complexâ€"in part preventable and treatable, but also in part unknown, and perhaps even unknowable. Guiding Cancer Control defines the key principles, attributes, methods, and tools needed to achieve the goal of implementing an effective national cancer control plan. This report describes the current structure of cancer control from a local to global scale, identifies necessary goals for the system, and formulates the path towards integrated disease control systems and a cancer-free future. This framework is a crucial step in establishing an effective, efficient, and accountable system for controlling cancer and other diseases.
