Translational Control in Biology and Medicine

Translational Control in Biology and Medicine PDF Author: Michael Mathews
Publisher: CSHL Press
ISBN: 0879697679
Category : Medical
Languages : en
Pages : 932

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Book Description
Updated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.

Translational Control in Biology and Medicine

Translational Control in Biology and Medicine PDF Author: Michael Mathews
Publisher: CSHL Press
ISBN: 0879697679
Category : Medical
Languages : en
Pages : 932

Get Book Here

Book Description
Updated and broadened 3rd edition. Since the last edition was published, the structures of the bacterial and eukaryotic ribosomes have been published, adding substantially to our knowledge of the basic mechanisms of translation. Understanding of how translation is regulated, by both protein and RNA regulators, has also advanced considerable. In addition, the current manifesttion of this volume has a significant focus on the role of translational control in human development and disease.

Sex Allocation

Sex Allocation PDF Author: Stuart West
Publisher: Princeton University Press
ISBN: 1400832012
Category : Science
Languages : en
Pages : 480

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Book Description
Recent decades have witnessed an explosion of theoretical and empirical studies of sex allocation, transforming how we understand the allocation of resources to male and female reproduction in vertebrates, invertebrates, protozoa, and plants. In this landmark book, Stuart West synthesizes the vast literature on sex allocation, providing the conceptual framework the field has been lacking and demonstrating how sex-allocation studies can shed light on broader questions in evolutionary and behavioral biology. West clarifies fundamental misconceptions in the application of theory to empirical data. He examines the field's successes and failures, and describes the research areas where much important work is yet to be done. West reveals how a shared underlying theoretical framework unites findings of sex-ratio variation across a huge range of life forms, from malarial parasites and hermaphroditic worms to sex-changing fish and mammals. He shows how research on sex allocation has been central to many critical questions and controversies in evolutionary and behavioral biology, and he argues that sex-allocation research serves as a key testing ground for different theoretical approaches and can help resolve debates about social evolution, parent-offspring conflict, genomic conflict, and levels of selection. Certain to become the defining book on the subject for the next generation of researchers, Sex Allocation explains why the study of sex allocation provides an ideal model system for advancing our understanding of the constraints on adaptation among all living things in the natural world.

A Review of Human Carcinogens

A Review of Human Carcinogens PDF Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Conference
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages :

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Book Description


Lime-trees and Basswoods

Lime-trees and Basswoods PDF Author: Donald Pigott
Publisher: Cambridge University Press
ISBN: 0521840546
Category : Nature
Languages : en
Pages : 411

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Book Description
Detailed descriptions are provided for all recognised taxa and are accompanied by illustrations.

Turfgrass

Turfgrass PDF Author: John C. Stier
Publisher: John Wiley & Sons
ISBN: 0891186131
Category : Technology & Engineering
Languages : en
Pages : 1348

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Book Description
Sustainability is a key framework for analyzing biological systems—and turfgrass is no exception. It is part of a complex that encompasses turfgrass interactions with different environments and the suitability of different turfgrasses for specific environments. In addition to its biological role, turfgrass—in the form of lawns, green spaces, and playing surfaces—brings beneficial sociological effects to an increasingly urbanized society. This book presents a comprehensive overview of current knowledge and issues in the field of turfgrass research and management, including the genetics and breeding, the diseases and pests, and the ecology of turfgrasses, and will appeal to a broad spectrum of readers.

Fitness Landscapes and the Origin of Species (MPB-41)

Fitness Landscapes and the Origin of Species (MPB-41) PDF Author: Sergey Gavrilets
Publisher: Princeton University Press
ISBN: 0691187053
Category : Science
Languages : en
Pages : 497

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Book Description
The origin of species has fascinated both biologists and the general public since the publication of Darwin's Origin of Species in 1859. Significant progress in understanding the process was achieved in the "modern synthesis," when Theodosius Dobzhansky, Ernst Mayr, and others reconciled Mendelian genetics with Darwin's natural selection. Although evolutionary biologists have developed significant new theory and data about speciation in the years since the modern synthesis, this book represents the first systematic attempt to summarize and generalize what mathematical models tell us about the dynamics of speciation. Fitness Landscapes and the Origin of Species presents both an overview of the forty years of previous theoretical research and the author's new results. Sergey Gavrilets uses a unified framework based on the notion of fitness landscapes introduced by Sewall Wright in 1932, generalizing this notion to explore the consequences of the huge dimensionality of fitness landscapes that correspond to biological systems. In contrast to previous theoretical work, which was based largely on numerical simulations, Gavrilets develops simple mathematical models that allow for analytical investigation and clear interpretation in biological terms. Covering controversial topics, including sympatric speciation and the effects of sexual conflict on speciation, this book builds for the first time a general, quantitative theory for the origin of species.

The Unified Neutral Theory of Biodiversity and Biogeography

The Unified Neutral Theory of Biodiversity and Biogeography PDF Author: Stephen P. Hubbell
Publisher: Princeton University Press
ISBN: 1400837529
Category : Science
Languages : en
Pages : 390

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Book Description
Despite its supreme importance and the threat of its global crash, biodiversity remains poorly understood both empirically and theoretically. This ambitious book presents a new, general neutral theory to explain the origin, maintenance, and loss of biodiversity in a biogeographic context. Until now biogeography (the study of the geographic distribution of species) and biodiversity (the study of species richness and relative species abundance) have had largely disjunct intellectual histories. In this book, Stephen Hubbell develops a formal mathematical theory that unifies these two fields. When a speciation process is incorporated into Robert H. MacArthur and Edward O. Wilson's now classical theory of island biogeography, the generalized theory predicts the existence of a universal, dimensionless biodiversity number. In the theory, this fundamental biodiversity number, together with the migration or dispersal rate, completely determines the steady-state distribution of species richness and relative species abundance on local to large geographic spatial scales and short-term to evolutionary time scales. Although neutral, Hubbell's theory is nevertheless able to generate many nonobvious, testable, and remarkably accurate quantitative predictions about biodiversity and biogeography. In many ways Hubbell's theory is the ecological analog to the neutral theory of genetic drift in genetics. The unified neutral theory of biogeography and biodiversity should stimulate research in new theoretical and empirical directions by ecologists, evolutionary biologists, and biogeographers.

Cell Biology of Addiction

Cell Biology of Addiction PDF Author: Bertha Madras
Publisher: CSHL Press
ISBN: 0879697539
Category : Medical
Languages : en
Pages : 478

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Book Description
This monograph, written by experts in the field, is devoted to the molecular analysis of addiction pathways in the brain. It provides an intensive overview of the fundamentals, state of the art advances, and major gaps in the cell and molecular biology of drug addiction within the broader context of neuroscience. Addiction research is a branch of neuroscience and psychology. The emphasis in this book is on hard science and the market for it will be found among research investigators and grad students within the field of neuroscience. The research presented is not only applicable to the study of drug abuse and addiction, but has clear implications for clarifying mechanisms of learning and memory, neuroadaptation, perception, volitional behavior, motivation, reward, and other disciplines of neuroscience.

Biology of Rhodococcus

Biology of Rhodococcus PDF Author: Héctor M. Alvarez
Publisher: Springer
ISBN: 9783642264948
Category : Science
Languages : en
Pages : 0

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Book Description
Rhodococcus, a metabolically versatile actinobacteria which is frequently found in the environment, has gained increasing interest due to its potential biotechnological applications. This Microbiology Monographs volume provides a thorough review of the various aspects of the biochemistry, physiology and genetics of the Genus Rhodococcus. Following an overview of its taxonomy, chapters cover the structural aspects of rhodococcal cellular envelope, genomes and plasmids, metabolic and catabolic pathways, such as those of aromatic compounds, steroids and nitriles, and desulfurization pathways, as well as the adaption to organic solvents. Further reviews discuss applications of Rhodococcus in the bioremediation of contaminated environments, in triacylglycerol accumulation, and in phytopathogenic strategies, as well as the potential of biosurfactants. A final chapter describes the sole pathogenic Rhodococcus member, R. equi.

Some Organophosphate Insecticides and Herbicides

Some Organophosphate Insecticides and Herbicides PDF Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: World Health Organization
ISBN: 9789283201502
Category : Carcinogens
Languages : en
Pages : 0

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Book Description
This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.