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Author: Kerry L. Jang
Publisher: Routledge
ISBN: 1135630712
Category : Medical
Languages : en
Pages : 388
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Book Description
New discoveries about the genetic underpinnings of many kinds of human experience are now continually being made. This book explores the impact of these discoveries on the ways in which the common mental disorders are best conceptualized and treated. Most people think of research in genetics as the search for genes. This is only one focus of effort, and even with the reliable identification of susceptibility genes, the clinical applications of their discovery, such as gene therapies and new drug development, are a long way off. For the present, the impact of genetic research on our understanding of mental illness is tied to our ability to estimate the effect of all genes by means of family, twin, and adoption studies. The results of these studies challenge some deeply cherished ideas and theories, and support others. Of course, the effect of genes is only half the equation. The role of experience, environment, and living conditions accounts for as much, often considerably more, of the variability in psychopathology. In this book, Kerry Jang attempts not to answer questions about what is "genetic" and what is not, but about what a knowledge of the relative influence of genes versus environment means at a psychological level of analysis--to show how it changes common assumptions about classification, etiology, diagnosis, and intervention. He first offers an overview of contemporary behavioral genetics, dispels common misconceptions, responds to the criticisms that have been leveled at this new field, and describes in basic terms how genetic and environmental effects are estimated and how susceptibility genes are pinpointed. He then points to new directions in which standard nosological systems are likely to evolve as new information about vulnerabilities and covariances emerges. Finally, he synthesizes and evaluates the consistency of the last decade's findings for the most common categories of psychopathology that have been studied by behavior geneticists: mood, personality, and anxiety disorders, substance abuse; and schizophrenia and the psychotic disorders. Clinicians and researchers alike need to understand the genetic influences on the feelings and behaviors they are seeking to change or study if they are to be effective in their work. The Behavioral Genetics of Psychopathology: A Clinical Guide empowers them with this understanding.
Author: Kerry L. Jang
Publisher: Routledge
ISBN: 1135630712
Category : Medical
Languages : en
Pages : 388
Get Book Here
Book Description
New discoveries about the genetic underpinnings of many kinds of human experience are now continually being made. This book explores the impact of these discoveries on the ways in which the common mental disorders are best conceptualized and treated. Most people think of research in genetics as the search for genes. This is only one focus of effort, and even with the reliable identification of susceptibility genes, the clinical applications of their discovery, such as gene therapies and new drug development, are a long way off. For the present, the impact of genetic research on our understanding of mental illness is tied to our ability to estimate the effect of all genes by means of family, twin, and adoption studies. The results of these studies challenge some deeply cherished ideas and theories, and support others. Of course, the effect of genes is only half the equation. The role of experience, environment, and living conditions accounts for as much, often considerably more, of the variability in psychopathology. In this book, Kerry Jang attempts not to answer questions about what is "genetic" and what is not, but about what a knowledge of the relative influence of genes versus environment means at a psychological level of analysis--to show how it changes common assumptions about classification, etiology, diagnosis, and intervention. He first offers an overview of contemporary behavioral genetics, dispels common misconceptions, responds to the criticisms that have been leveled at this new field, and describes in basic terms how genetic and environmental effects are estimated and how susceptibility genes are pinpointed. He then points to new directions in which standard nosological systems are likely to evolve as new information about vulnerabilities and covariances emerges. Finally, he synthesizes and evaluates the consistency of the last decade's findings for the most common categories of psychopathology that have been studied by behavior geneticists: mood, personality, and anxiety disorders, substance abuse; and schizophrenia and the psychotic disorders. Clinicians and researchers alike need to understand the genetic influences on the feelings and behaviors they are seeking to change or study if they are to be effective in their work. The Behavioral Genetics of Psychopathology: A Clinical Guide empowers them with this understanding.
Author: Lisabeth F. DiLalla
Publisher: Amer Psychological Assn
ISBN: 9781591470830
Category : Psychology
Languages : en
Pages : 239
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Book Description
Behavior Genetics Principles: Perspectives in Development, Personality, and Psychopathology presents work that addresses both historical and novel approaches to the study of genetic and environmental influences on behavior. Contributors to this volume use behavior genetics as a means for understanding the etiology of mental illness as well as normal development. They ask: what genes predispose a person to develop a specific personality trait? What about an inclination to a psychological disorder? How do environmental factors enhance or mute genetic factors? Do they regulate inherited individual differences in behavior and personality throughout a lifetime? Behavior Genetics Principles explores the many connections between genes, personality, development, and psychopathology. It focuses on research influenced by Irving I. Gottesman, a pioneer in behavioral genetics research. As a mentor and a colleague, Gottesman has worked to examine the role of genes and environmental factors using both traditional and novel study designs and analytic methods. This stimulating volume, by colleagues who have helped shape the field of behavioral genetics, presents cutting edge work that carries on h
Author: Valerie S. Knopik
Publisher:
ISBN: 9781319174927
Category : Behavior genetics
Languages : en
Pages : 550
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Book Description
Author: Kenneth S. Kendler
Publisher: Guilford Press
ISBN: 1593856458
Category : Psychology
Languages : en
Pages : 434
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Book Description
This groundbreaking volume synthesizes the results of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders, which yielded longitudinal data on more than 9,000 individuals. The authors trace how risk for depression, anxiety, eating disorders, antisocial behavior, alcoholism, and substance abuse emerges from the interplay of a variety of genetic and environmental influences. Major questions addressed include whether risk is disorder-specific, how to distinguish between correlational and causal genetic and evironmental factors, sex differences in risk, and how risk and protective factors interact over time. The book also summarizes the conceptual underpinnings of the study and describes key methodological challenges and innovations.
Author: Kimberly J. Saudino
Publisher: Springer Nature
ISBN: 1071609335
Category : Psychology
Languages : en
Pages : 356
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Book Description
This volume examines behavioral genetic research on temperament and personality from a number of perspectives. It takes a developmental perspective on a number of issues across the lifespan, focusing on personality and temperament. The first section focuses on the development of temperament and personality. Typically this has involved exploring genetic and environmental contributions to phenotypic stability and instability, but more recently there has been research that examines the etiology of intra-individual change/growth trajectories. The second section examines genetic and environmental contributions to the association between temperament and personality and other behaviors. The third and fourth sections discuss genotype-environment correlations and interactions, and introduces the reader to molecular genetics research on temperament and personality. Chapter 11 will discuss the significance of this type of research and Chapter 12 will provide an example of specific line of research exploring genes associated with temperament.
Author: Yong-Kyu Kim
Publisher: Springer Science & Business Media
ISBN: 0387767274
Category : Medical
Languages : en
Pages : 557
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Book Description
This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.
Author: James J. Hudziak
Publisher: American Psychiatric Pub
ISBN: 1585628808
Category : Medical
Languages : en
Pages : 312
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Book Description
A major benchmark in the understanding of psychiatric illness in children and adolescents, Developmental Psychopathology and Wellness reports on progress in identifying genetic and environmental influences on emotional-behavioral disorders. A team of 22 international authorities presents work that changes the way child psychiatry and clinical psychology are conceptualized, debunking misconceptions about depression, antisocial behavior, and other conditions to enhance our understanding of the causes of child psychopathology -- and improve the ways we treat these disorders. Coverage of basic principles describes the influence of genomic medicine, as explained by trailblazers in the field who demonstrate the importance of the developmental perspective. Chapters on gene-environment interaction review the important concepts of personality and temperament, cognition, and sex -- including findings from molecular genetic investigations on adolescent cognition, temperament, and brain function. Disorder-based examples show how emotional-behavioral illness and wellness attest to the interaction of genetic and environmental factors over time, providing new insight into the study of anxious depression, ADHD, autism, and antisocial personality disorders. And in considering how we can bridge the gap between research and clinical applications, Dr. Hudziak describes his family-based gene-environment approach as a means of better understanding etiopathology and treatment. Among the other significant contributions: Thomas Achenbach focuses on the importance of culture in understanding the genetic and environmental impact on children, with insights into measuring these sources of influence. Joan Kaufman reports on her seminal work on the genetic and environmental modifiers of risk and resilience in child abuse, relating maltreatment to other forms of environmental risk, genetic mediation, and reactivity. D. I. Boomsma describes the genetic architecture of childhood worry, presenting data from an extraordinary sample of 30,000 twin pairs. Frank Verhulst draws on a 14-year study to detail the advantages of the developmental perspective in understanding antisocial behavior. Stephen Faraone offers guidelines for moving beyond statistics to document the functional significance of DNA variants associated with psychopathology. As the contributors ably demonstrate, these new approaches to the care and treatment of at-risk children are applicable to daily practice, teaching, and research. Developmental Psychopathology and Wellness shows that these psychopathologies are not a matter of nature versus nurture or genes versus environment, but rather an intertwining web of them all.
Author: Michael W. Vasey
Publisher: Oxford University Press
ISBN: 0195352513
Category : Psychology
Languages : en
Pages : 527
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Book Description
Anxiety disorders are among the most prevalent forms of psychopathology across the life span. Although the onset of such disorders may occur at almost any point, in many cases they begin in childhood. In this book, the editors have brought together many of the field's most respected and innovative researchers and challenged them to take a fresh look at the major factors that contribute to the etiology and maintenance of anxiety disorders in childhood and across the life span. The result is a collection of chapters that will stimulate further theoretical and empirical efforts regarding these important issues.
Author: Benjamin L. Hankin
Publisher: SAGE
ISBN: 1452236577
Category : Psychology
Languages : en
Pages : 521
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Book Description
"..a blending of two important approaches to understanding psychopathology- the developmental approach and the vulnerability approach. I think a book like this is timely, is needed, and would be of interest to professors who teach courses in psychopathology at the advanced undergraduate and graduate levels." — Robin Lewis, Old Dominion University "Bringing together developmental psychopathology frameworks and the vulnerability-stress models of psychological disorders is an excellent idea. I am aware of no other book that incorporates these two approaches. Having taught Psychopathology courses for both master′s and doctoral students, I reviewed many books to recommend and use in the courses. It is my belief that a book of this type is needed particularly for graduate students." —Linda Guthrie, Tennessee State University Edited by Benjamin L. Hankin and John R. Z. Abela, Development of Psychopathology: A Vulnerability-Stress Perspective brings together the foremost experts conducting groundbreaking research into the major factors shaping psychopathological disorders across the lifespan in order to review and integrate the theoretical and empirical literature in this field. The volume editors build upon two important and established research and clinical traditions: developmental psychopathology frameworks and vulnerability-stress models of psychological disorders. In the past two decades, each of these separate approaches has blossomed. However, despite the scientific progress each has achieved individually, no forum previously brought these traditions together in the unified way accomplished in this book. Key Features: Consists of three-part text that systematically integrates vulnerability-stress models of psychopathology with a developmental psychopathological approach. Brings together leading experts in the field of vulnerability, stress, specific vulnerabilities to psychological disorders, psychopathological disorders, and clinical interventions. Takes a cross-theoretical, integrative approach presenting cutting-edge theory and research at a sophisticated level. Development of Psychopathology will be a valuable resource for upper-division undergraduate and graduate students in clinical psychology, as well as for researchers, doctoral students, clinicians, and instructors in the areas of developmental psychopathology, clinical psychology, experimental psychopathology, psychiatry, counseling psychology, and school psychology.
Author: Jonathan Benjamin
Publisher: American Psychiatric Pub
ISBN: 1585627607
Category : Medical
Languages : en
Pages : 452
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Book Description
In the 1960's and 1970's, personality and mental illness were conceptualized in an intertwined psychodynamic model. Biological psychiatry for many un-weaved that model and took mental illness for psychiatry and left personality to psychology. This book brings personality back into biological psychiatry, not merely in the form of personality disorder but as part of a new intertwined molecular genetic model of personality and mental disorder. This is the beginning of a new conceptual paradigm!! This breakthrough volume marks the beginning of a new era, an era made possible by the electrifying pace of discovery and innovation in the field of molecular genetics. In fact, several types of genome maps have already been completed, and today's experts confidently predict that we will have a smooth version of the sequencing of the human genome -- which contains some 3 billion base pairs Such astounding progress helped fuel the development of this remarkable volume, the first ever to discuss the brand-new -- and often controversial -- field of molecular genetics and the human personality. Questioning, critical, and strong on methodological principles, this volume reflects the point of view of its 35 distinguished contributors -- all pioneers in this burgeoning field and themselves world-class theoreticians, empiricists, clinicians, developmentalists, and statisticians. For students of psychopathology and others bold enough to hold in abeyance their understandable misgivings about the conjunction of "molecular genetics" and "human personality," this work offers an authoritative and up-to-date introduction to the molecular genetics of human personality. The book, with its wealth of facts, conjectures, hopes, and misgivings, begins with a preface by world-renowned researcher and author Irving Gottesman. The authors masterfully guide us through Chapter 1, principles and methods; Chapter 4, animal models for personality; and Chapter 11, human intelligence as a model for personality, laying the groundwork for our appreciation of the remaining empirical findings of human personality qua personality. Many chapters (6, 7, 9, 11, and 13) emphasize the neurodevelopmental and ontogenetic aspects of personality, with a major emphasis on the receptors and transporters for the neurotransmitters dopamine and serotonin. Though these neurotransmitters are a rational starting point now, the future undoubtedly will bring many other candidate genes that today cannot even be imagined, given our ignorance of the genes involved in the prenatal development of the central nervous system. Chapter 3 provides an integrative overview of the broad autism phenotype, and as such will be of special interest to child psychiatrists. Chapters 5, 8, and 10 offer enlightening information on drug and alcohol abuse. Chapter 14 discusses variations in sexuality. Adding balance and mature perspectives on how all the chapters complement and sometimes challenge one another are Chapter 2, written by a major figure in the renaissance of the relevance to psychopathology of both genetics and personality; Chapters 15-17, informed critical appraisals citing concerns and cautions about premature applications of this information in the policy arena; and Chapter 18, a judicious contemplation by the editors themselves of this promising -- and, to some, alarming -- field. Clear and meticulously researched, this eminently satisfying work is written to introduce the subject to postgraduate students just beginning to develop their research skills, to interested psychiatric practitioners, and to informed laypersons with some scientific background.
