Test No. 310: Ready Biodegradability - CO2 in sealed vessels (Headspace Test) PDF Download
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Author: OECD
Publisher: OECD Publishing
ISBN: 9264016317
Category :
Languages : en
Pages : 18
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Book Description
This Test Guideline is a screening method for the evaluation of ready biodegradability of chemical
Author: OECD
Publisher: OECD Publishing
ISBN: 9264016317
Category :
Languages : en
Pages : 18
Get Book Here
Book Description
This Test Guideline is a screening method for the evaluation of ready biodegradability of chemical
Author: OECD
Publisher: OECD Publishing
ISBN: 9264224505
Category :
Languages : en
Pages : 18
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Book Description
This Test Guideline is a screening method for the evaluation of ready biodegradability of chemicals.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264303219
Category :
Languages : en
Pages : 41
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Book Description
The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264185291
Category :
Languages : en
Pages : 72
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Book Description
This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264303235
Category :
Languages : en
Pages : 36
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Book Description
The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264264310
Category :
Languages : en
Pages : 23
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Book Description
The Potamopyrgus antopodarumon reproduction test is designed to assess potential effects of prolonged exposure to chemicals on reproduction and survival of parthenogenetic lineages of the freshwater mudsnail Potamopyrgus antipodarum. Adult female P. antipodarum are exposed to a concentration ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264886109
Category :
Languages : en
Pages : 45
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Book Description
The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b promoter. The EASZY assay allows for the detection of estrogenic activity of chemicals on transgenic tg(cyp19a1b:GFP) Zebrafish embryos exposed for 96 hours during the embryonic stages of development.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264264337
Category :
Languages : en
Pages : 31
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Book Description
This Test Guideline is designed to assess effects of prolonged exposure to chemicals on the reproduction and survival of the hermaphrodite freshwater snail Lymnaea stagnalis (the Great Pond Snail).
Author: OECD
Publisher: OECD Publishing
ISBN: 9264242341
Category :
Languages : en
Pages : 38
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Book Description
This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...
Author: OECD
Publisher: OECD Publishing
ISBN: 9264916784
Category :
Languages : en
Pages : 42
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Book Description
The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of thyroid hormone available for transcription. The test is based on the use of a transgenic frog (possessing the genetic construction THb/ZIP-GFP) of the species X. laevis. GFP is a fluorescent protein that can be used to affirm the presence of the substance and to follow its action. This test is based on the quantification of fluorescence, and thus of the GFP protein, throughout the eleutheroembryo exposed to a test chemical. Indeed, if the fluorescence is > 12% by including the highest concentration of the test, the test is considered positive. Organisms are exposed in chemically inert cell culture plates (6 wells). Each well contains ten organisms in solution. In a run, 20 organisms are exposed to each test concentration. Tadpoles are exposed to the test chemical at NF stage 45 for a duration of 72 hours. A positive result of the XETA test indicates in vivo that a substance induces damage to the receptor and metabolization of the thyroid hormone. A negative result indicates that, under test conditions, the test substance does not induce detectable damage to the thyroid and its functioning.
