Systems Biology and Its Application in TCM Formulas Research PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Systems Biology and Its Application in TCM Formulas Research PDF full book. Access full book title Systems Biology and Its Application in TCM Formulas Research by Weidong Zhang. Download full books in PDF and EPUB format.
Author: Weidong Zhang
Publisher: Academic Press
ISBN: 0128127457
Category : Medical
Languages : en
Pages : 382
Get Book Here
Book Description
Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. - Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases - Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology - Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research
Author: Weidong Zhang
Publisher: Academic Press
ISBN: 0128127457
Category : Medical
Languages : en
Pages : 382
Get Book Here
Book Description
Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. - Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases - Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology - Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research
Author: James D Adams
Publisher: Royal Society of Chemistry
ISBN: 1782624937
Category : Science
Languages : en
Pages : 363
Get Book Here
Book Description
Traditional Chinese medicine has a strong scientific basis, but the science of these important preparations is often rarely discussed. Western approaches often simplify traditional Chinese medicine to drug discovery in Chinese plants, however, the majority of traditional Chinese medications use complex mixtures of plant extracts, rather than single purified drugs. The combination of different extracts is based on yin, yang and chi theories, which are often poorly understood in the West. Yin and yang are known to be the balance of agonists and antagonists, whereas chi derives from signalling processes in the body and regulates bodily functions. Traditional Chinese medical practitioners understand that yin, yang and chi constantly interact in the body to maintain health. Western medical practitioners understand how to use agonists and antagonists and how to modify signalling processes, but generally do not accept the use of complex plant extracts to perform these functions. Aimed at medical scientists, and including detailed explanations of the theories behind the science, this text may help researchers to understand Chinese medical practitioners and to communicate more effectively with them. It will also lead to greater acceptance of traditional medications in the West. Presenting a clear rationale for the use of traditional Chinese medications in Western medical facilities, it enables scientists to find new directions in experimental design and encourage examination of these useful, but often poorly understood, preparations in clinical trials.
Author: Guoan Luo
Publisher: John Wiley & Sons
ISBN: 1118313356
Category : Science
Languages : en
Pages : 518
Get Book Here
Book Description
The application of systems biology methods to Traditional Chinese Medicine Emphasizing the harmony of the human body with the environment, Traditional Chinese Medicine (TCM) has evolved over thousands of years. It is a systemic theory derived from clinical experience, the philosophy of holism and systematology, and the belief that man is an integral part of nature. Systems Biology for Traditional Chinese Medicine describes how the latest methods in systems biology can be applied to TCM, providing a comprehensive resource for the modernization and advancement of TCM as well as general drug discovery efforts. It is the first comprehensive work to propose a system-to-system research methodology to study the interaction between TCM and the human body and its applications in drug research and development. Using three popular traditional Chinese medicines—Shuanglongfang, Qingkailing, and Liushenwan—as examples, the authors set forth case examples demonstrating how to find material groups, perform efficacy screenings, and conduct safety evaluations of TCM. The book also: Describes the mechanisms of TCM at the molecular and systems levels using chemomics, genomics, proteomics, metabolomics, and bioinformatics Places modern scientific technologies within the context of TCM, helping drug researchers improve experimental designs and strategies Illustrates how a systems biology approach is compatible with TCM's traditional, holistic therapeutic strategies and treatment modalities Presents topics of current interest, such as integrated global systems biology and the application of chemometrics research to herbal medicines This book not only opens a new pathway for the continued development of TCM, but also for systems biology. In addition, it fosters collaboration and discussion among Eastern and Western scientists by applying systems biology to TCM.
Author: Shao Li
Publisher: Springer Nature
ISBN: 9811607532
Category : Medical
Languages : en
Pages : 480
Get Book Here
Book Description
This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Author: Maoshing Ni
Publisher: Shambhala Publications
ISBN: 0834825767
Category : Health & Fitness
Languages : en
Pages : 339
Get Book Here
Book Description
The Neijing is one of the most important classics of Taoism, as well as the highest authority on traditional Chinese medicine. Its authorship is attributed to the great Huang Di, the Yellow Emperor, who reigned during the third millennium BCE. This new translation consists of the eighty-one chapters of the section of the Neijing known as the Suwen, or "Questions of Organic and Fundamental Nature." (The other section, called the Lingshu, is a technical book on acupuncture and is not included here.) Written in the form of a discourse between Huang Di and his ministers, The Yellow Emperor's Classic of Medicine contains a wealth of knowledge, including etiology, physiology, diagnosis, therapy, and prevention of disease, as well as in-depth investigation of such diverse subjects as ethics, psychology, and cosmology. All of these subjects are discussed in a holistic context that says life is not fragmented, as in the model provided by modern science, but rather that all the pieces make up an interconnected whole. By revealing the natural laws of this holistic universe, the book offers much practical advice on how to promote a long, happy, and healthy life. The original text of the Neijing presents broad concepts and is often brief with details. The translator's elucidations and interpretations, incorporated into the translation, help not only to clarify the meaning of the text but also to make it a highly readable narrative for students—as well as for everyone curious about the underlying principles of Chinese medicine.
Author: Edwin L. Cooper
Publisher: Springer Science & Business Media
ISBN: 9780306482885
Category : Health & Fitness
Languages : en
Pages : 514
Get Book Here
Book Description
This volume is the proceedings of an international symposium that examined the newest parameters in alternative and complementary medicine, thus covering a rapidly growing field of medicine that has strong advocates as well as strong opponents. Topics include both basic research and clinical applications, allowing the text to present high quality, peer reviewed, chapter style contributions that dispel some of the pseudoscience and myth surrounding alternative and complimentary medicine.
Author: Friedrich G. Wallner
Publisher: Peter Lang Gmbh, Internationaler Verlag Der Wissenschaften
ISBN: 9783631567098
Category : Manners and customs
Languages : en
Pages : 0
Get Book Here
Book Description
This volume presents texts written by Austrian and Chinese experts in the field of Traditional Chinese Medicine. The issue the authors worked on is the basic problem how to make a different system of medical thinking plausible for the Western world, especially for Western medicine. This issue is considered from different viewpoints - from the viewpoint of Western medicine that is familiar with Chinese medicine and contrariwise from the viewpoint of Chinese Medicine that is familiar with its Western counterpart and from a philosophical viewpoint. In this way both differences in the theoretical systems of Western and Chinese medicine and problems of adequate translation are profundly discussed.
Author: Weici Tang
Publisher: Springer Science & Business Media
ISBN: 3642737390
Category : Medical
Languages : en
Pages : 1005
Get Book Here
Book Description
Traditional Chinese medicine has been used for thousands of years by a large population. It is currently still serving many of the health needs of the Chinese people; and still enjoying their confi dence it is practised in China in parallel with modern Western medical treatment. In addition to scientific organisations dedi cated to modern Western medicine, e. g. the Chinese Academy of Medical Sciences and various medical schools, a series of parallel institutions have been established in China to promote traditional Chinese medicine, such as the Academy of Traditional Chinese Medicine and training institutions. Almost all hospitals in China have a department of traditional medicine. Furthermore, a large number of scientific journals are dedicated to traditional Chinese medicine, covering both experimental and clinical investigations. Medicinal materials constitute a key topic in the treatment of disease according to traditional Chinese medicine. The Chinese Pharmacopoeia (1985 edition) is therefore divided into two sepa rate volumes, Volume I containing traditional Chinese medicinal materials and preparations and Volume II containing pharmaceu tics of Western medicine. The oldest Chinese review of medicinal materials, Shennong Bencao Jing (100-200 A. D. ), covered 365 herbal drugs. The clas sic compilation in this field, Bencao Gangmu (Compendium of Materia Medica), was published in 1578 by Li Shi-zhen and recorded as many as 1898 crude drugs of plant, animal and min eral origin.
Author: Sun-Chong Wang
Publisher: World Scientific
ISBN: 9814412880
Category : Medical
Languages : en
Pages : 379
Get Book Here
Book Description
Modern Western Medicine (MWM) and Ayurveda/Traditional Chinese Medicine (TCM) can be considered two extreme paradigms to complex systems. The microscopic and reductionist approach of the West prevails in acute and single-gene conditions such as infection and Mendelian disorders. The macroscopic and holistic approach of the East potentially fares well at chronic and complex conditions such as obesity and ageing. The book serves three purposes: 1) to help MWM, Ayurveda and TCM professionals get acquainted with one another; 2) to help identify common grounds for MWM, Ayurveda and TCM, rather than blindly westernizing eastern medicines or vice versa; and 3) to help translate the complementarity of MWM and Ayurveda/TCM toward an integrative multi-component healthcare. To this end, we introduce theories and tenets of the three medicines. We use bioenergetics to reconcile West and East as ATP generation, prana and qi are central to MWM, Ayurveda and TCM. We discuss clinical trials of varying experimental rigors for the assessment of the scientific evidence for treatment effectiveness. We present complementary interventions for chronic disorders and ageing. We hold that a federal unity of therapies consisting of MWM, Ayurveda and TCM better serves the wellbeing of humankind.
Author: H.Gerhard Vogel
Publisher: Springer Science & Business Media
ISBN: 3540898905
Category : Medical
Languages : en
Pages : 576
Get Book Here
Book Description
Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
