Systemic Fibroinflammatory Disorders

Systemic Fibroinflammatory Disorders PDF Author: Augusto Vaglio
Publisher: Springer
ISBN: 331941349X
Category : Medical
Languages : en
Pages : 248

Get Book Here

Book Description
This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement. Among the conditions considered are IgG4-related disease, sclerosing cholangitis, Hashimoto’s and Riedel’s thyroiditis, retroperitoneal fibrosis/chronic periaortitis, mediastinal fibrosis, Erdheim-Chester disease, gadolinium-induced fibrosis, and sclerosing mesenteritis. This group of entities is still poorly defined and is characterized by the common denominator of chronic inflammatory infiltrate admixed with abundant fibrosis. IgG4-related disease is the prototypical example. Systemic Fibroinflammatory Disorders is the first book to draw together information on these conditions. As these diseases often require an interdisciplinary approach, the book is addressed to specialists of different disciplines, especially internists, rheumatologists, nephrologists, clinical immunologists, and hematologists.

Systemic Fibroinflammatory Disorders

Systemic Fibroinflammatory Disorders PDF Author: Augusto Vaglio
Publisher: Springer
ISBN: 331941349X
Category : Medical
Languages : en
Pages : 248

Get Book Here

Book Description
This book provides detailed information on the nosology, pathology, pathogenesis, clinical presentation, diagnosis and treatment of fibro-inflammatory disorders, rare diseases that often display systemic organ involvement. Among the conditions considered are IgG4-related disease, sclerosing cholangitis, Hashimoto’s and Riedel’s thyroiditis, retroperitoneal fibrosis/chronic periaortitis, mediastinal fibrosis, Erdheim-Chester disease, gadolinium-induced fibrosis, and sclerosing mesenteritis. This group of entities is still poorly defined and is characterized by the common denominator of chronic inflammatory infiltrate admixed with abundant fibrosis. IgG4-related disease is the prototypical example. Systemic Fibroinflammatory Disorders is the first book to draw together information on these conditions. As these diseases often require an interdisciplinary approach, the book is addressed to specialists of different disciplines, especially internists, rheumatologists, nephrologists, clinical immunologists, and hematologists.

IgG4-Related Sclerosing Cholangitis

IgG4-Related Sclerosing Cholangitis PDF Author: Terumi Kamisawa
Publisher: Springer
ISBN: 9811045488
Category : Medical
Languages : en
Pages : 141

Get Book Here

Book Description
This book aims to raise awareness of IgG4-related sclerosing cholangitis among practicing physicians and to equip readers with a sound understanding of the principles of diagnosis and treatment. Clinical, serological, and histopathological features are clearly described and imaging appearances on all relevant modalities are illustrated, covering the bile duct and other involved organs. Differential diagnosis from other diseases, including primary sclerosing cholangitis and cholangiocarcinoma, is precisely explained. Information is then presented on all significant current and emerging therapeutic strategies, including steroids, immunosuppressive drugs, and rituximab. Finally, attention is drawn to significant prognostic features. While IgG4-related sclerosing cholangitis is now a widely acknowledged condition, most practitioners are still liable to misdiagnose it owing to a lack of familiarity with its presenting features. This book should help to rectify the situation and will be an asset for all who may encounter the disease in clinical practice.

IgG4-Related Kidney Disease

IgG4-Related Kidney Disease PDF Author: Takao Saito
Publisher: Springer
ISBN: 4431556877
Category : Medical
Languages : en
Pages : 298

Get Book Here

Book Description
This book offers a detailed review of the pathological and imaging features, diagnosis and treatment of IgG4-Related Kidney Disease (IgG4-RKD). IgG4-related disease (IgG4-RD), which is characterized by an elevated serum IgG4 level and infiltration of systemic organs by IgG4 positive plasma cells, is a newly recognized systemic disease. Diverse renal manifestations including specific tubulointerstitial nephritis, membranous nephropathy, and tumor-like urological diseases extending to the pelvis and urinary tract in IgG4-RD have been reported and are recently attracting attention as IgG4-RKD. In this book, leading researchers in the field present the latest insights into the broad spectrum of IgG4-RKD characteristics. In addition, they provide a detailed explanation of the pathology of IgG4-RKD including comparisons between the kidney and other affected organs, such as the lacrimal, salivary glands and pancreas in the histopathological section. IgG4-Related Kidney Disease will have a major impact on future immunological and nephrological studies and offers a useful resource not only for nephrologists but also general physicians and investigators in related fields.

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae

The Origin of Chronic Inflammatory Systemic Diseases and their Sequelae PDF Author: Rainer Straub, MD
Publisher: Academic Press
ISBN: 9780128033210
Category : Medical
Languages : en
Pages : 390

Get Book Here

Book Description
Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting - cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation-related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress . The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging. Offers a broad conceptual framework with a strong clinical link, written in an easy to grasp style and demonstrating the link to aging research Describes the important principles derived from basic immunology that are used to explain pathogenesis of chronic inflammatory systemic diseases with a focus on autoimmunity Defines the bioenergetics and energy regulation of the body explaining common response pathways typical for systemic inflammation Makes use of evolutionary medicine theory to demonstrate the uniformity of the systemic response Explains the appearance of typical disease sequelae on the basis of the three pillars: neuroendocrine immunology, energy regulation, and evolutionary medicine theory Contains color figures and tables that explain the field to newcomers

Diseases of the Brain, Head and Neck, Spine 2020–2023

Diseases of the Brain, Head and Neck, Spine 2020–2023 PDF Author: Juerg Hodler
Publisher: Springer Nature
ISBN: 303038490X
Category : Medical
Languages : en
Pages : 252

Get Book Here

Book Description
This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Pathology of Bone and Joint Disorders Print and Online Bundle

Pathology of Bone and Joint Disorders Print and Online Bundle PDF Author: Edward F. McCarthy
Publisher: Cambridge University Press
ISBN: 1107041236
Category : Medical
Languages : en
Pages : 385

Get Book Here

Book Description
Fully updated new edition covering all aspects of bone and joint diseases in one easily readable volume. Color illustrations throughout.

Histiocytic Disorders

Histiocytic Disorders PDF Author: Oussama Abla
Publisher: Springer
ISBN: 3319596322
Category : Medical
Languages : en
Pages : 391

Get Book Here

Book Description
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.

Rare and Interesting Cases in Pulmonary Medicine

Rare and Interesting Cases in Pulmonary Medicine PDF Author: Ali Ataya
Publisher: Academic Press
ISBN: 0128097671
Category : Science
Languages : en
Pages : 246

Get Book Here

Book Description
Rare and Interesting Cases in Pulmonary Medicine provides a look into the uncommon diseases encountered in the field of pulmonary medicine. Using a case-based approach, the book provides clinical scenarios that include relevant accompanying radiology and pathology. Also included are frequently asked questions for each area, as well as a diagnosis and summary, presenting the reader with the most high yield information on each topic. Appropriate for medical students, residents, fellows, and physicians interested in pulmonary medicine, the case-based approach to each topic allows accessibility to the uncommon diseases of the field while also highlighting high yield and important points. Provides case-based approaches to the uncommon diseases of pulmonary medicine, including supporting radiology and pathology Includes uncommon case studies, providing relevant references for further reading and research opportunities Presents related topics with accompanying clinical pearls for direct application in the field

The Sclera and Systemic Disorders

The Sclera and Systemic Disorders PDF Author: Peter G Watson
Publisher: JP Medical Ltd
ISBN: 1907816070
Category : Medical
Languages : en
Pages : 380

Get Book Here

Book Description
This book guides ophthalmologists through interpretation of Optical Coherence Tomography (OCT) images, which are cross-sectional images captured through non-invasive, non-contact imaging technology. Begins with analysis of the subdivides of each image into its smallest components, followed by a combination of these fine details to allow diagnosis and identification of appropriate treatment; features detailed schematic illustrations as well as actual scans, and offers information on technical and clinical uses of OCT in study of glaucoma and 3D images. Full of high-quality images, this is a must-have for all practicing and training ophthalmologists and optometrists.

Clinical Oral Medicine and Pathology

Clinical Oral Medicine and Pathology PDF Author: Jean M. Bruch
Publisher: Springer Science & Business Media
ISBN: 1603275207
Category : Medical
Languages : en
Pages : 176

Get Book Here

Book Description
Clinical Oral Medicine and Pathology, is a clinically relevant and accessible resource for health care professionals that truly bridges the worlds of dentistry and medicine. This handbook of oral medicine and oral pathology serves as a highly readable guide for diagnosis and treatment of commonly encountered oral conditions. The volume is organized by grouping clinical entities under easily recognizable, diagnostically related headings and subheadings and allows the busy clinician to quickly reference and identify a lesion of interest. Concise descriptions of each entity provide background information and treatment recommendations while including specific guidelines on diagnosis, management, and follow-up. The authors of this text both have extensive training in the fields of oral pathology, dentistry, oral surgery and otolaryngology, and provide a comprehensive approach to the practice of oral medicine for all those who are likely to encounter diseases of the oral cavity in their daily practice.